Objective To investigate the prevalence of Schistosoma japonicum infections in wild rodents in schistosomiasis-endemic areas of China, so as to provide insights into formulation of technical guidelines for monitoring of and the precise control strategy for S. japonicum infections in wild rodents during the elimination phase. Methods Two administrative villages where schistosomiasis was historically highly prevalent were selected each from Dongzhi County, Anhui Province, and Duchang County, Jiangxi Province as study villages. Wild rodents were captured from study villages with baited traps or cages at night in June and September, 2021. The number of rodents captured was recorded, and the rodent species was characterized based on morphologi-cal characteristics. Liver tissues were sampled from captured rodents for macroscopical observation of the presence of egg granu- lomas, and S. japonicum infection was detected simultaneously using liver tissue homogenate microscopy, examinations of mesenteric tissues for parasites, and modified Kato-Katz thick smear technique (Kato-Katz technique). A positive S. japonicum infection was defined as detection of S. japonicum eggs or adult worms by any of these methods. The rate of wild rodent capture and prevalence of S. japonicum infections in wild rodents were compared in different study villages and at different time periods, and the detection of S. japonicum infections in wild rodents was compared by different assays. Results The overall rate of wild ro- dent capture was 8.28% (237/2 861) in Dongzhi County, and the wild rodent capture rates were 9.24% (133/1 439) and 7.31% (104/1 422) in two study villages (χ² = 3.503, P = 0.061), and were 8.59% (121/1 409) and 7.99% (116/1 452) in June and September, 2021, respectively (χ² = 0.337, P = 0.561). The overall rate of wild rodent capture was 3.72% (77/2 072) in Duchang County, and the wild rodent capture rates were 6.91% (67/970) and 0.91% (10/1 102) in two study villages (χ² = 51.901, P < 0.001), and were 4.13% (39/945) and 3.37% (38/1 127) in June and September, 2021, respectively (χ² = 0.815, P = 0.365). Rattus norvegicus was the predominant rodent species captured in both counties, accounting for 70.04% (166/237) of all captured wild rodents in Dongzhi County and 88.31% (68/77) in Duchang County. No S. japonicum infection was detected in wild rodents captured in Duchang County. Nevertheless, the overall prevalence of S. japonicum infections was 51.05% (121/237) in wild rodents captured in Dongzhi County, with prevalence rates of 50.38% (67/133) and 51.92% (54/104) in two study villages (χ² = 0.098, P = 0.755), and 54.31% (63/116) and 47.93% (58/121) in September and June, 2021, respectively (χ² = 0.964, P = 0.326). Of 237 wild rodents captured in Dongzhi County, there were 140 (59.07%) rodents with visible hepatic egg granulomas, 117 (49.47%) tested positive for S. japonicum eggs by liver tissue homogenate microscopy, 34 (14.35%) tested positive for S. japonicum eggs with Kato-Katz technique; however, no adult S. japonicum worms were detected in mesenteric tissues. In addition, hepatic egg granulomas were found in all wild rodents tested positive for S. japonicum eggs with liver tissue homogenate microscopy. Conclusions The rate of wild rodent capture and prevalence of S. japonicum infection in wild rodents vary greatly in schistosomiasis-endemic areas of China, and the prevalence of S. japonicum infection is slightly higher in wild rodents captured in autumn than in summer. Liver tissue is recommended as the preferred sample for surveillance of S. japonicum infection in wild rodents, and a combination of macroscopical observation of hepatic egg granulomas and liver tissue homogenate microscopy may be a standard method for surveillance of S. japonicum infection in wild rodents.

Objective To investigate the prefrontal lobe function in patients with bipolar disorder with impulsive aggressive behavior using magnetic resonance spectroscopy (MRS),so as to explore the possible relationship between impulsive aggressive behavior and prefrontal brain function in patients with bipolar disorder from the perspective in brain function.Methods A total of 24 patients with bipolar disorder (10 cases with impulsive aggressive behavior,and 14 with non-impulsive aggressive behavior) were enrolled in the study.The modified overt aggression behavior scale (MOAS) and the Barratt Impulsiveness Scale 11 (BIS-11) were used to evaluate the included subjects.Magnetic resonance spectroscopy (MRI) scans were performed on the subjects using 3.0T magnetic resonance imaging equipment to analyze quantitatively N-Acetyl-L-aspartic acid/Cr (NAA/Cr),choline/Cr (Cho/Cr),and glutamine and/or glutamic acid/Cr (Glx/ Cr) ratios.Results The left prefrontal NAA/Cr value in patients with bipolar disorder was significantly lower in impulsive aggressive behavior group than that in non-impulsive aggressive behavior group,and the difference was statistically significant (P ＜ 0.05);however,there was no obvious statistical difference in the comparison of the right prefrontal NAA/Cr value,as well as left and right prefrontal values of Cho/Cr and GlX/Cr between impulsive aggressive behavior group and non-impulsive aggressive behavior group.Conclusions The NAA/Cr value is significantly abnormal in the left prefrontal cortex of bipolar disorder patients with impulsive aggressive behavior (P ＜ 0.05),suggesting that there may exist decreased density of neurons in the left side of prefrontal lobe or dysfunction of neurons in bipolar disorder patients with impulsive aggressive behavior.

Objective To explore the effects of self-made traditional Chinese medicine ( TCM ) concentrate for sponge bath and feet bath on postpartum recovery in parturients with cesarean section. Methods A total of 300 parturients with cesarean section were selected as subjects from July 2014 to December 2015 and were randomly divided into three groups including group A ( 100 cases, sponge bath and feet bath with TCM), group B (100 cases, feet bath with warm water), group C (100 cases, without intervention) with informed consent according to bed numbers. We observed the volume of lochia, height of fundus, the time of first flatus, milk yield, sleep quality, length of stay among groups after childbirth. And then, we explored the effects of self-made TCM concentrate for sponge bath and feet bath on postpartum recovery in parturients with cesarean section by comparing indicators among groups.Results The volume of lochia, height of fundus, the time of first flatus, milk yield, sleep quality in group A were better than those in group B and C with significant differences (P<0.05) along with the length of stay in group A 0.5-1 d less than that in group B and C.Conclusions The self-made TCM concentrate for sponge bath and feet bath can reduce the length of stay and contribute to reducing the volume of lochia post partum, promoting the involution of uterus and intestinal peristalsis, increasing the milk yield, improving sleep quality, relieve postoperative pain so as to promote postpartum recovery.

OBJECTIVE: To explore the clinical manifestations, diagnosis and treatment of primary thyroid B cells lymphoma. METHOD: Eight cases of primary thyroid B cells lymphoma were retrospectively analysed, which were combinely diagnosed and treated. RESULT: Follow up was being for two to seven years. Three cases were loss of visit, one case died, and four cases survived. Two-year survival rate was 85.1%, and five-year survival rate was 76.3%. CONCLUSION A combination of various diagnostic and therapeutic methods of primary thyroid B cells lym-phoma can improve the diagnosis rate, reduce the misdiagnosis rate and improve the curative effect.
Aged ; Female ; Humans ; Lymphoma, B-Cell ; diagnostic imaging ; surgery ; Middle Aged ; Retrospective Studies ; Thyroid Neoplasms ; diagnostic imaging ; surgery ; Ultrasonography