1.Sanqi-Tongshu capsule's effect on hemodynamics in patients with acute cerebral infarction
International Journal of Traditional Chinese Medicine 2011;33(9):786-787
ObjectiveTo observe the effects of Sanqi-Tongshu capsule on the hemodynamics in patients with acute cerebral infarction (blood rheology, blood lipids), and to explore the clinical efficacy.Methods60 patients diagnosed of cerebral infarction by clinical and CT scan were randomized into a contrast group and a treatment group, with 30 patients in each group. The contrast group was treated with conventional western medicine the treatment group was treated with Sanqi-Tongshu capsule based on the contrast group. Hemorheology and blood lipid changes were observed before and after treatment. Results After the treatment,the treatment group's blood rheology [high shear whole blood (3.89±0.16) mpa·s, low-shear whole blood (8.12±0.06) mpa·s, erythrocyte aggregation index (1.164±0.24), erythrocyte rigidity index (3.53±0.40) ] and blood lipids [cholesterol (5.84± 0.92) mmol/L, triglycerides (1.54± 0.23) mmmmol/L, low-density lipoprotein (2.12 ± 0.54) mmol/L] showed statistical significance(all P<0.05)compared with the contrast group.ConclusionSanqi-Tongshu capsule can effectively improve the blood theology and lipid metabolism It is an effective drug for the treatment of acute cerebral infarction.
3.Efficacy of purging the lung and removing phlegm and blood stasis method(泻肺化痰祛瘀法) on rats with pulmonary hypertension
Huiqun PANG ; Xudong XIONG ; Hui ZHAO
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2006;0(03):-
Objective: To study the efficacy of purging the lung and removing phlegm and blood stasis method(泻肺化痰祛瘀法) on animal model of pulmonary hypertension induced by monocrotaline and explore its mechanism.Methods: The model of pulmonary hypertension induced by monocrotaline was established in rats.Sixty healthy and clean male Wistar rats were randomly divided into normal control group,model group,low and high dosage of traditional Chinese medicine(TCM) drugs for purging the lung and removing phlegm and blood stasis groups.From the 15 th day after model establishment,two dosage groups were treated with the drugs in the prescription containing the main ingredients as follows: 9 g prepared rhubarb(制大黄),(2 g)(prepared)(euphorbia) kansui(炙甘遂),15 g lepidium apetalum(葶苈子),9 g ligusticum(川芎) and 15 g(scutellaria)(黄芩) infused into the stomach once a day for 7 days.Normal control group and model group were given normal saline infused into the stomach.Mean right ventricular pressure(MRVP) and the mean(pulmonary) artery pressure(MPAP) of rats were measured by right cardiac catheterization,and the(pathological)(changes) of lung tissues were detected by hematoxylin and eosin(HE) stained sections.(Results:) The MRVP and the MPAP in high dosage group((13.37?4.22)mm Hg and(12.26?2.79) mm Hg,(1 mm Hg)=(0.133 kPa)) were lower than that in the model group((16.27?2.27) mm Hg and(14.77?(2.39) mm Hg),P
4.A clinical study for radiotherapy positioning with references images on CT simulator
Bo YANG ; Xiaoyang SUN ; Huiqun LUO ; Hong WU ; Haowen PANG
Chinese Journal of Radiation Oncology 2011;20(1):54-56
Objective To explore a new method of comparing the references images first to enhance the precision of the central point of the radiation treatment planning(RTP), try to establish a reference standard for this method in the nasopharyngeal cancer(NPC)and carcinoma of utercin cervix in the work of position verification. Methods For 50 RTPs of NPC and 20 RTPs of carcinoma of utercin cervix, the reference-CT-images in set-up and in position verification were compared, and to measure the difference between the two images. Then, in the same way, compare and measure the difference in the central-pointimages. Results For NPC, there was over 90% RTPs in which every difference measured was less than 2 mm;for carcinoma of utercin cervix, over 80% RTPs meet the criterion:the value of △MU1 ' or △MU2' was less than 5 mm and the others are less than 3 mm. Conclusions By comparing the references-CT-images in set-up and in position verification, the precision of the central point of the RTP is enhanced. The marks on the skin become more credible. So, it is feasible to perform the criterions in the work of position verification:for NPC every difference measured is less than 2 mm;for carcinoma of utercin cervix the value of △MU1 ' or △MU2 ' is less than 5 mm and the others are less than 3 mm.