Objective To obtain the normal reference value through researching ?HU of CT scanning symetric cerebral structrue among healthy group and to study its value in CT diagnosing super acute cerebral infarction.Methods 33 volunteers with normal neuro system were undertaken routine plain CT scanning to measure the symetric cerebral structrue on 7 pairs of tissues of each person and caculated 231 ?HUs. All the data were analyzed statistically to get a normal reference value, which was compared with the ?HU of 30 super acute cerebral infarction cases (33 suspected symptoms)confirmed by follow-up.Results The mean?HU of CT scanning symetric cerebral structrue among healthy group was 0.39 with Q=0.48(?HU) a maximum of 1.79 (?HU) and minimum of 0.00 (?HU). Among the pathological change group, the mean ?HU of CT value was 3.62 with Q=2.44 (?HU), a maximum of 8.34(?HU) and minimum of 1.2 (?HU). There was significant difference between the ?HUs of 7 pairs of cerebral tissues of each person in normal group and those of the pathological change group(P

ObjectiveTo assess the value of plain X-ray radiography,CT and MRI in the diagnosis of synovial oateochondromatosis.MethodsTwenty patients with synovial osteochondromatosis confirmed with surgery and pathology were enrolled.The images of X-rays (n= 18),CT (n=20) and MRI (n= 10) were analyzed retrospectively.ResultsDefinite diagnosis was made in 15 patients according to plain X-ray radiography,in 18 patients according to CT findings,while in 8 patients according to MRI manifestations.Plain X-ray radiography,CT and MRI could show loose bodies around/within the involved joints in various shape,size and different amount.Plain X-ray radiography and CT could show calcification of loose bodies.MRI could show early cartilage loose bodies.CT and MRI could display effusion of the involved joints.ConclusionPlain X-ray radiography,CT and MRI are able to diagnose synovial osteochondromatosis.CT and MRI can depict lesions and characteristics that impossible for X-ray radiography.

BACKGROUND:Continuous monitoring is required in the survival, distribution, migration, proliferation and differentiation of transplanted stem cel s in vivo thereby to assess its efficacy and safety.
OBJECTIVE:To analyze the characteristics of literature addressing stem cel markers and MRI tracer in the past 10 years.
METHODS:The first author retrieved CNKI and Web of Science by computer for articles about MRI tracing of stem cel s published from January 2005 to December 2014, using the keywords of“stem cel s, magnetic resonance imaging, tracing technique”that appeared in the title and abstract. Then, the retrieved articles were further analyzed.
RESULTS AND CONCLUSION:Currently, tracing technique has been widely used in stem cel therapy, organ transplantation, bacterial infection, gene expression and new drug development. Stem cel tracing technologies include isotope tracing, antigenic labeling, fluorescence protein labeling, fluorescent dye labeling, nuclear magnetic resonance contrast enhancer labeling, Lac-Z gene labeling, Y chromosome labeling. Recently, with the development of molecular imaging, MRI tracing techniques have been increasingly used to assess the efficacy and safety of stem cel transplantation.

PurposeAdult intussusception is rare, and clinical symptoms are atypical and tend to be misdiagnosed. This study aims to explore the imaging features of intussusception on multi-slice CT (MSCT) and to improve the diagnosis of this disease. Materials and Methods Sixty cases with intussusception conifrmed by pathology were recruited and imaging ifndings including sleeve head lesions, set sheath canal, exhumation of intestine, involved mesenteric fat, and blood vessels were retrospectively analyzed. Results The direct sings included 60 cases with target signs, 44 of them with single target signs and 16 of them with double target signs; the shape was kidney like in 39 cases and irregular in 21 cases; 22 cases showed double intestinal signs, 15 cases showed comet tail signs, and 25 cases showed mountain like with different direction. The indirect signs included 60 cases with thickened intestinal wall and 45 cases with mesenterium fat and vessel in enteric cavity, 12 cases with adjacent mesenteric mass and enlarged retroperitoneal lymph nodes, 15 cases with ascites, 7 cases with metastatic tumors, including 4 cases of liver metastasis, 2 of pelvic ossiifcation metastasis, and 1 of multiple organ metastasis, 1 case combined with renal calculus and 3 case with ureteral caluli. Conclusion There are some special CT manifestations of adult intussusception. Mountain like sign with different direction at the tail is one of the characteristics. CT plays an important role in clinical procedure.

Objective To investigate the effects of total alkaloids in Buxus microphylla leaves (ABML) on isolated rats thoracic aorta rings,and then to explore the possible mechanisms underlying the effects.MethodsThoracic aortas of Wistar rats were isolated,removed,and mounted onto an organ bath.The effects of ABML at different concentration on the contraction of isolated thoracic aorta rings (with and without endothelium) precontracted with KC1 or PE were observed with organ bath technique.Dose-effect curves of CaCl2 were recorded by organ bath technique.The concentration of intracellular Ca2+ ([Ca2+]i) increased by PE,KCI,and caffeine in the presence of ABML was determined using Ca2+ sensitive fluorescence indicator Fura-2/AM loaded thoracic aorta vascular smooth muscle (VSM) cells of rats.ResultsIn aorta rings precontracted with PE and KCI,ABML produced concentrationdependent relaxation in both intact and denuded endothelium ring groups.There was no difference in the inhibition of contraction between the intact and denuded endothelium ring groups at the same concentration.Exposure of isolated thoracic aorta rings to ABML led to a significant reduction in the contracting response induced by CaCI2,and shifted the cumulative concentration-response curves to right.ABML could significantly inhibit the extracellular Ca2+ influx induced by PE and KCI under [Ca2+]0 of 1.5 mmol/L,with inhibitory ratios of 40.2％ and 49.9％,respectively.In the case of Ca2+-free,ABML could significantly inhibit the intracellular Ca2+ release induced by PE,with inhibitory ratio of 72.4％.ConclusionABML relaxes thoracic aorta VSM cells by suppressing influx of extracellular Ca2+ via voltage-dependent Ca2+ channel and receptor-operated Ca2+ channel.

Objective To observe the MRI characteristics in subacute combined degeneration (SCD)of the spinal cord.Methods The data of 1 9 SCD patients were retrospectively analyzed by the clinical characteristics and MR images.Results Among the 1 9 pa-tients of SCD,1 6 cases showed abnormal findings.Most of intramedullary lesions located in posterior column of thoracic and cervical spinal cord,and only one case located in cerebellar cortex and medulla oblongata.Lesions were involved in muti-segmental spinal cord,and mainly located in the dorsal or lateral spinal cord,and only two cases located in the anterior spinal cord.Different segmental spinal cord lesions had a different morphological characteristics with no enhancement.After treatments with vitamin B1 2 ,the lesions diminished and even disappeared in 2 cases.Conclusion MRI has important value in the diagnosis and treatment monitor of the SCD.

Objective To study the method and effectiveness of interventional therapy for the stenotic or obstructive inferior vena cava(IVC) caused by hepatic cancer. Methods All together 6 patients were enroled, 4 males and 2 females, with age of 45 to 58 years, average 53 years. The main symptoms including abdominal distention, varices on abdominal walls and edema in lower extremities were caused by compression or involvement of IVC with right hepatic lobe lesion. We performed thrombolysis first and follower by balloon dilation and stent placement. Results IVC were recanalized in all 6 patients with free patent blood flow. The postal venous pressure dropped from 4.4 kPa to 2.1 kPa without major complications. Conclusions Treating the IVC stenosis and obstruction caused by primary liver cancer with interventional method is safe and effective together with improvement of life quality and prolongation of survival time. (J Intervent Radiol, 2006, 15: 537-538)

Objective To observe the effect of ginkolide B derivative(XQ) on animal thrombosis.Methods SD male rats were randomized into the model group,troxerutin(48 mg?kg-1?d-1) group,ginkolide B(7.8 mg?kg-1?d-1) group,and low-,middle-and high-dose XQ(in the dose of 3.9,7.8 and 15.6 mg?kg-1?d-1 respectively) groups.The anti-thrombotic effect of XQ was observed on rats mixed thrombosis model induced by arterio-venous shunt method and electrical stimulation.Meanwhile,ICR male mice were randomized into the model group,troxerutin(96 mg?kg-1?d-1) group,ginkolide B(15.6 mg?kg-1?d-1) group,and low-,middle-and high-dose XQ(in the dose of 7.8,15.6 and 31.2 mg?kg-1?d-1 respectively) groups.The anti-thrombotic effect of XQ was also observed on mice acute pulmonary embolism model induced by adenosine diphosphate(ADP).Results XQ at the dose of 7.8 and 15.6 mg?kg-1?d-1 decreased the dry and wet weight of the thrombosis,and obviously prolonged the formation time of rats carotid artery thrombosis as compared to the model group(P

Objective To evaluate the applied values of susceptibility weighted imaging (SWI) in acute ischemic stroke.Methods Totally 40 patients with acute ischemic stroke were included within 72 hours after symptom onset.They adopted multimodal magnetic resonance imaging examination,including regular magnetic resonance imaging sequence (T1WI,T2WI),time of flight MR angiography (TOF-MRA),diffusion weighted imaging (DWI) and susceptibility weighted imaging (SWI).Furthermore,12 of the 40 patients received dynamic susceptibility contrast enhanced perfusion weighted imaging (DSCPWI) examination.Results Of the 40 patients,12 ones had positive results for multiple lesions of cerebral microbleeds (CMBs) by SWI,and the detection rate was 30％.There were 24 patients showed susceptibility vessel sign (SVS) in SWI,and the susceptibility rate was 60％.In the 12 patients received DSC-PWI examination simultaneously,there were 7 cases had the anomaly range by SWI larger than that by DWI while similar to that by DSC-PWI.Conclusion SWI can show SVS and CMBs clearly,estimate ischemic penumbra,know intracranial conditions completely and supply reliable basis for individualized treatment.