1.The violence risk assessment of the community patients with severe mental illness and Logistic regression analysis on associated factors
Chinese Journal of Behavioral Medicine and Brain Science 2012;(11):1029-1031
Objective To assess the violence risk levels of the community patients with severe mental illness and Analyze the associated factors.Methods A working group composed of psychiatrists,community police,FIMITIC staff,community physicians,neighborhood or village committee members was established.501 community patients with severe mental illness were evaluated with Violence Risk Assessment Scale by working group.While the data of the general demograpbic,medical history and violence history was investigated.Logistic regression analysis was used to explore the factors associated with violence.Results In 501 patients,risk levels of grade 0:124cases (24.8%),grade 1:165 cases (32.9%),grade 2:118 cases (23.5%),grade 3:59 cases (11.8%),grade 4:28 cases (5.6%) and grade 5:7 cases (1.4%).Logistic regression analysis showed four significant risk factors,which were schizophrenia (OR 4.139),no taking medicine (OR 6.883),unstable condition (OR 234.534) the number of previous violence(OR 3.457) (P < 0.05).Logistic regression equation:Logit (severe violence) =-8.511 + 1.420 (schizophrenia) + 1.929 (no taking medicine) + 5.458 (unstable condition) +1.241 (the number of previous violence).Conclusion The results of violence risk assessment and risk factors have directive significance for management of community patients with severe mental illness.
2.The effect of thiopental anasthsia on T lymphocyte snbsets in mice
Yan WANG ; Huiming ZUO ; Fanrong ZENG
The Journal of Clinical Anesthesiology 2001;17(4):211-212
ObjectiveTo observe the effect of thiopental on T lymphocyte subsets in mice. MethodsT lymphocyte subsets were measured by flow cytorneter and monoclonal antibodies and immunofluorescence technic. ResaltsThe CD4 T cell and the CD4/CD8 ratio decreased after thiopental anaesthesia in mice. At the same time the whole amount of white blood cells has no statistical significant difference between test group and control group. ConclusionThiopental anaesthesia inhibits immune function.
3.Determination of the Contents of Puerarin in Infant Fuxieling Effervescent Granules With HPLC
Bihua LU ; Yuqiao WANG ; Huiming ZHANG
China Pharmacy 2001;12(4):238-239
OBJECTIVE: To establish a method for determination of the contents of puerarin in infant Fuxieling effervescent granules with HPLC.METHODS:The puerarin was extracted by ultrasonics, using methanol as solvate.The stratographic column was Shim - Pack C1s with acetonitrile - water( 10: 90) as mobile phase. The flow rate was 2.0ml/min and the detecting wavelenghth was 250nm.The temperature of column was 25℃ .RESULTS:The resolution between the puerarin and the adjacent peaks was >1.5 .The number of theoretical plates was 18 550 .The standard curve was linear in the range of 0.964μg~7. 712μg .The average recovery was 100.2% (RSD = 1.76%, n = 6).CONCLUSION:The method is simple, rapid and accurate. It can be used for quality control of the preparation.
4.Correlation between end-tidal carbon dioxide tension and arterial carbon dioxide pressure in traumatic patients
Huiming WANG ; Jihong SHI ; Weiqing MA
Chinese Journal of Trauma 2003;0(08):-
0.05). PetCO 2 was a reliable index reflecting PaCO 2. There was a significant difference between PetCO 2 and PaCO 2 in the Group Ⅲ (P
5.Expression of Vascular Endothelial Growth Factor Receptor Kinase Inser Domain Containing Receptor in Human Cervical Carcinoma
Huiming DI ; Fenglian XU ; Dong WANG
Chinese Journal of Obstetrics and Gynecology 2000;0(11):-
Objective To observe the expression of vascular endothelial growth factor receptor (KDR)in human cervical carcinomas, to clarify the relationship between the expression and invasion, metastasis, prognostic value in human cervical carcinoma. Methods KDR was stained immunohistochemically in 80 cases of human cervical carcinoma. Results The expression of KDR in the endothelial cells of tumor vasculature is: the high KDR expression rate of clinical cancer stages ≤Ⅰb and Ⅱa~Ⅲa was 21 4% and 60 6% (P
6.Researches of Effects of Phthalate Esters on Rodents and Human
Xiaoyi WANG ; Xingtao LIN ; Huiming KE
Journal of Environment and Health 2007;0(09):-
Phthalate esters have been used as the plasticizers for about 80 years. As a kind of environmental hormone and universal pollutants, they are found widely in air dust, industrial waste water, river, soil and solid waste, moreover, they have been detected in food, drinking water and body fluid. In this paper, the new progresses of the effects of phthalate esters on the rodents and human, including reproductive toxicity and liver toxicity, were summarized and the short-term, quick and accumulative actions of phthalates mono-esters, metabolite of phthalate esters, on the rodents and human body were also reviewed.
7.Determinations of symptomatical fractured vertebrae in treating osteoporotic vertebral compression fractures with vertebroplasty and pitfalls as well as preventive strategy
Hong LIU ; De WANG ; Huiming ZHI
Orthopedic Journal of China 2006;0(18):-
[Objective]Osteoporotic vertebral compression fractures(OVCFs)are commonly multiple fractures and this study is aimed to explore how to determine the symptomatical fractured vertebrae as well as the pitfalls in treating OVCFs using percutaneous vertebroplasty(PVP).[Method]Forty-eight OVCFs patients(78 vertebrae)undergoing PVP were retrospectively analyzed.All the patients had anteroposterior and lateral plain X-rays as well as T1W1,T2W1 and fat-compressing(STIR)MR images preoperatively.The symptomatical fractured vertebrae were determined with combination of regional pain、X-rays and MR images.Of all the patients,36 were injected unilaterally while 12 were injected bilaterally.The mean injected volume of PMMA were 3-7 ml.[Result]The back pain of all the patients were relieved to different degrees postoperatively.The back pain completely disappeared in 30 patients while the left back pain was not improved though the right back pain disappeared in 2 patients who were injected via right approach.The back pain almost disappeared but the bilateral rib pain was not improved in 1 patient with T8 vertebral fracture.No severe complications including pulmonary emboli occurred.[Conclusion]The symptomatical fractured vertebrae should be determined comprehensively not only based on preoperative X-rays but also on the MR images,especially fat-compressing MR images.Only when the fractured vertebrae demonstrate low intensity on T1W1 MR image and high-intensity on T2W1 or fat-compressing MR image can we consider them new fractures.Otherwhise,the fractured vertebrae are considered old fractures and they see no necessity to be injected.The injection should reach the most severely fractured part and if necessary the bilateral approaches are considered.PMMA should be injected after the bone cements are solid enough so as not to develop complications such as pulmonary emboli.
8.Effect of VEGF over-expressed C6 glioma cells on the expression of Flk-1 and Flt-1 in cocultured microvascular endothelial cells
Xinhong WANG ; Lianhua YIN ; Huiming JIN
Chinese Journal of Pathophysiology 2000;0(11):-
AIM: To study the effects of VEGF over-expressed C6 glioma cells on the expression of Flk-1 and Flt-1 in cocultured microvascular endothelial cells using the rat hepatic cells BRL 3A as control. METHODS: Cocultured systems of rat pulmonary microvascular endothelial cells with C6 and endothelial cells with BRL 3A were established. Immunocytochemical method was used to investigate the expression change of Flk-1 and Flt-1 protein in cocultured microvascular endothelial cells. The expression of Flt-1 and Flk-1 mRNA was analyzed by RT-PCR and Northern blot. RESULTS: The microvascular endothelial cells cocultured with C6 showed increased expression of Flk-1 and Flt-1 protein ( P
9.Effects of different penetration enhancer on penetration of ciclopirox olamine and salysic acid in percutaneous penetration
Xiaolong FENG ; Hui WANG ; Huiming ZHU
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(01):-
AIM: To study the enhancing effect of penetration enhancer on percutaneous absorption of antifungal agents. METHODS: Percutaneous penetration experiment was performed on device in vitro, and the deposit effects were observed with vivoperception. RESULTS: Combination of 1-menthol (1%) and azone (1%) showed the best effect on percutaneous absorption of cidopicox olamine, and 1-menthol (1%) had the best effect on percutaneous absorption of salysic acid. The compound penetration enhancer, consisting of 1-menthol (1%), azone (1%), propylene glycol ( 2.5%) and oleic acid ( 2.5%), had prominent action on absorption of cidopirox olamine through rabbit skins, and shorten the lag times obviously. CONCLUSION: L-menthol and azone can significantly enhance the percutaneous absorption of both salysic acid and cidopicox olamine. Combination of 1-menthol and azone can further increase the absorption.c
10.EFFECT OF DIFFERENT SURFACE CONDITIONING METHODS ON SHEAR BONDING STRENGTH OF GLASS-INFILTRATED CERAMIC I TO DENTINE
Fei LI ; Huiming HE ; Zhongyi WANG
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
To investigate the effects of different surface conditioning methods on the shear bonding strength of glass-infiltrated ceramic to dentine, 24 glass-infiltrated ceramic testing-pieces were divided into four groups randomly. Among them 3 groups were treated with A(sandblasting+silance), B(etching+silace) or C(silance), separately, while group D was set as the control. Bonding the ceramic pieces to dentine with Super-Bond and the shear bonding strengths was measured. The results showed that the shear bonding strength of group D was lower than that of group A, B and C (P0.05). It is suggested that surface conditioning using combined sandblasting with silance can remarkbly improve the shear bonding strength of glass-infiltrated ceramic to dentine.