Objective To study the changed status of mortality from urinary and male genital diseases in Shanghai Hongkou district in recent years. Methods Mortality from diseases in Shanghai Hongkou district population from 1991 to 1998 was studied and analyzed. Results There were 1130 persons died of urinary and male genital diseases,749 being male and 381 female.It accounted for 2.08% of the total death,being 2.58% in the male and 1.51% in the female.The 5 major urinary and male genital diseases were in turn nephritis and nephropathy,bladder cancer,benign prostatic diseases,prostate cancer and renal carcinoma.Mortality from bladder cancer,renal cancer,prostate cancer and other prostatic diseases has been rising as compared to those in the 80s especially protatic cancer and other prostatic diseases whereas mortality from nephritis and nephropathy,pyelonephritis and renal failure was decreasing. Conclusions Mortality from prostate cancer and other prostatic diseases in population is remarkably rising.Attention is called to the study,prophylaxis and treatment of prostatic diseases.

Objective To explore the factors influencing pregnancy outcome of gestational diabetes mellitus (GDM) patients with isolated fasting hyperglycemia.Methods Medical records of 1 059 GDM patients with isolated fasting hyperglycemia,who gavc birth at Peking University First Hospital between January 2012 and December 2015,were retrospectively reviewed.Clinical data,including maternal age,pre-pregnancy body mass index (BMI),fasting plasma glucose (FPG) in the first trimester,results of oral glucose tolerance tests (OGTT),area under the curve (AUC) of OGTT,glycosylated hemoglobin (HbAlc),re-tested FPG (within one week after OGTT) and insulin usage,were analyzed.Patients with or without adverse pregnancy outcome,including first cesarean section,larger for gestational age,preterm birth,hypertensive disorders of pregnancy,dystocia or birth trauma,neonatal hypoglycemia and neonatal hyperbilimbinemia,were respectively divided into two groups.T or Chi-square test was used for univariate analysis.Logistic regression was used for multivariate analysis.Results Among the 1 059 patients,18 (1.7％) received insulin therapy and 591 had adverse pregnancy outcome (55.8％).Univariate analysis showed that the percentages of patients whose age ≥ 35 years old,pre-pregnancy BMI ≥ 25,AUC ≥ 13 mmol/L · h or HbAlc ≥ 5.5％ were higher in the group with adverse pregnancy outcome than in those without adverse pregnancy outcome [21.7％ (128/591) vs 13.2％ (62/468),x2=12.548;28.9％ (171/591) vs 16.2％ (76/468),x2=23.535;87.5％ (517/591) vs 78.4％ (367/468),x2=15.542;32.9％ (155/471) vs 26.2％ (99/377),x2=4.514;all P＜0.05].The average values of OGTT-1 h and OGTT-2 h in patients with adverse pregnancy outcome were higher than in those without [(8.27 ± 1.14) vs (8.11 ±-1.19) mmol/L,t=-0.367;(7.01 ±0.85) vs (6.88±0.87) mmol/L,t=-0.517;both P＜0.05].Multivariate analysis showed that pre-pregnancy BMI＜25 and AUC＜13 mmol/L · h were protective factors for adverse pregnancy outcomes [OR (95％CI):0.498 (0.355-0.698) and 0.431 (0.247-0.752),both P＜0.01].Conclusions Pre pregnancy BMI＜25 and AUC＜13 mmol/L · h are protective factors for adverse pregnancy outcomes in GDM patients with isolated fasting hyperglycemia.Clinical practitioners may regard this group of women as relatively low-risk to avoid unnecessary intervention.

Objective To examine the development of traditional Chinese medicine (TCM) in China and provide reference for the construction of a discipline through a literature review of TCM physique and statistical analyses of papers published between 2008 and 2017. Methods We searched the Chinese journal full?text database for TCM physique research papers, and used bibliometrics to statistically analyze the papers. Results We obtained 2 905 papers from 381 journals, 1 021 institutions, and 6 740 authors. The number of papers increases with the publication time. The cited rate was 87.2%. Each paper was cited 8.74 times. The H?index was 51 and co?authored rate was 83.7%. The cooperation degree was 3.78 with 3 354 words appearing in the keywords of the papers. Conclusion In the past ten years, research on TCM constitution has advanced, strengthening core scientific research. Research quality is high, and the research contents cover a wide range. With the spread of research tentacles, the prospect of further research on this subject is worth looking forward to.

OBJECTIVE： To analyze the development situation of pharmacoeconomic evaluation research in China， and to provide reference for pharmacoeconomics discipline construction. METHODS： China journal full-text database was searched by computer. The searching time was from database establish to Dec. 2018. After collecting the academic papers with the theme of “pharmacoeconomic evaluation”， statistical analysis was made on publication year， source journals， institutions， authors， cooperation publication， citation information and keywords of papers by bibliometric method. RESULTS & CONCLUSIONS： A total of 1 197 literatures were included. The earliest literature was published in 1993， and the largest number （104 pieces） was published in 2015. The literatures came from 289 journals. Among which， China Pharmacy published the largest number of literatures （123 pieces）； the first author came from 619 institutions， which mainly were China Pharmaceutical University （124 pieces）； a total of 2 352 authors were involved， and 923 literatures were completed by two or more authors， with co-authorship rate of 77.1％. The total number times of authors was 3 480， and the degree of cooperation was 2.91. As of April 19， 2019， 975 literatures had been cited. The cited rate was 81.4％， the average citation frequency was 5.83 times， and the H-index was 29. There were a total of 1 922 keywords in the literatures， the top three keywords in the list of frequency were pharmacoeconomics （805 times）， cost-effectiveness analysis （209 times）， and pharmacoeconomic evaluation （98 times）. It could be seen that the research literatures on pharmacoeconomic evaluation in China were published earlier and widely distributed； the research content of the literatures was comprehensive， and some literatures had high influence. But the total number of literatures is still small and is distributed unevenly， and the number of core authors is insufficient， and related research needs to be further developed.

Objective: To study the computational fluid dynamics (CFD) characteristics of ultrasonic root canal irrigation when the file was placed at a certain depth in the root canal, to provide a reference for clinical application. Methods : First, scanning laser vibrometry (SLV) was utilized to analyze the characteristics of vibrational ultrasonic files under specific power. Then ICEM CFD 18.0 software was used to establish the root canal ultrasonic irrigation model. The insertion position of the ultrasonic working tip was set 1 mm away from the physiological apical foramen, and cloud images of the results were obtained by FLUENT 18.0 software. Volume fraction, flow velocity and pressure in the root canal were evaluated after setting the computing conditions. Results: The vibration of the ultrasonic working tip was mainly transverse vibration with slight longitudinal vibration. The amplitude of transverse vibration of each part of the working tip was different. Maximum values were observed at the apical end area of the file, and the closer to the base of the file, the smaller the amplitude. The area where the cavitation volume fraction of the rinsing fluid was greater than 0 was concentrated around the working point. The flow rate of the irrigating fluid was up to 2 m/s, within the area 0.2 mm in front of the working tip, the velocity of the irrigating fluid was greater than 0.1 m/s, while within the area 0.8 mm from the root tip, the velocity of the irrigating fluid was small or even zero. The apical pressure value was non-positive when the tip of the file was 1 mm away from the apical foramen in this model. Conclusion Based on the experimental results, it appears that when the ultrasonic working tip was placed 1 mm short of the working length, the ultrasonic irrigating flow did not overflow the root apical foramen and the irrigation process was relatively safe; the irrigation fluid had a strong irrigation effect within approximately 0.2 mm in front of the working tip.

OBJECTIVEIn China, the coverage rate of work injury insurance was 23.2%in 2011, which was far lower than expected. The factors affecting the insurance's enrollment has very little known. This paper aims to study the existing coverage of work injury insurance scheme and its influencing factors.

METHODSThe data were collected from 2 836 workers who came from 9 industries in three cities of Zhejiang province using face-to-face questionnaire interview.

RESULTSOf these 2836 workers, the work injury insurance coverage was 50.1%, and 29.6% were not sure if they were covered or not. The results showed that the awareness of occupational disease and industrial injury insurance was helpful in increasing the coverage rate. Besides, the logistic regression analysis showed that in certain circumstances working population shared higher coverage of work injury insurance. For examples, male workers with local household registration and longer working years; people who had been informed about occupational risk factors, and thus gained more training on the issue; people who had exposed to occupational hazards or involved in administrative duties; and people who had already insured by a medical insurance scheme. In the contrary, the heavier family burden with longer working hours per week they needed, the lower possibility they joined the insurance scheme.

CONCLUSIONSThe coverage of work injury insurance is higher than native average level but much lower than the average international level. The awareness of occupational disease and injury insurance was closely associated with the coverage of work injury insurance. Therefore, it is imperative to popularize the knowledge on OHS for migrant workers, as well as to reinforce the supervision and management of the issue would have been an effective way to elevate the coverage rate of work injury insurance.

China ; Cities ; Health Services Needs and Demand ; Humans ; Insurance Coverage ; statistics & numerical data ; Male ; Occupational Diseases ; Surveys and Questionnaires ; Transients and Migrants

OBJECTIVETo investigate workers' willingness to participate and wiliness to pay for a hypothetical industrial injury insurance scheme, to analyze the influential factors, and to provide information for policy making of the government.

METHODSMultistage cluster sampling was used to select subjects: In the first stage, 9 small, medium, orlarge enterprises were selected fromthree cities (counties) in Zhejiang province, China, according to the level of economic development, transportation convenience, and cooperation of government agencies; in the second stage, several workshops were randomly selected from each of the 9 enterprises. Face-to-face interviews among all workers in the workshops were conducted by trained interviewers using a pre-designed questionnaire.

RESULTSIt was found that 73.87% (2095) of all workers were willing to participate in the hypothetical work injury insurance scheme and to pay 2.21% of monthly wage (51.77 yuan) on average, and more than half of the workers were willing to pay less than 1%of monthly wage (35 yuan). Of the 741 workers who were not willing to participate, 327 thought that the premium should be borne by the state or enterprises, instead of individuals, and others were not willing to participate because of low income, unstable job, or poor understanding of the hypothetical industrial injury insurance scheme. Logistic regression analysis showed that workers with higher education levels, longer length of services, longer weekly working time, or more knowledge of occupational diseases showed higher willingness to participate in the scheme; workers who were exposed to physical hazards, had health records, or had participated in the existing medical insurance or industrial injury insurance were more willing to participate. Multiple linear regression analysis showed that with increasing average monthly wage, weekly working time, and self?health evaluation, the proportion of workers with willingness to pay increased; however, with increasing work intensity and awareness of occupational disease, the proportion of workers with willingness to pay decreased. The workers who were not covered by the industrial injury insurance paid more than those covered by the industrial injury insurance.

CONCLUSIONThe hypothetical industrial injury insurance scheme increased the applicability and advantage of independent third-party running and lifetime insurance, which significantly increased the workers' willingness to participate in or to pay for the insurance scheme. Therefore, the industrial injury insurance can be improved in these aspects to promote workers' willingness to participate in and to pay for the insurance scheme. This conclusion provided a reference for the solution of delayed or shirking corporate responsibility for paying the premium.

Accidents, Occupational ; economics ; Attitude to Health ; China ; Cluster Analysis ; Financing, Personal ; Health Policy ; Humans ; Insurance ; Insurance, Health ; economics ; utilization ; Models, Theoretical ; Occupational Diseases ; economics ; Surveys and Questionnaires