Objective To explore the value of ultrasonographic on fetal limb deformities in prenatal diagnosis by using systemat-ic continuous sequence approach(SCSA) Methods During the period of January 2008 to April 2012 ,SCSA with color doppler ultra-sonography was used to screen 41 460 pregnant women in order to observe the four limbs of the fetus .And compared with the limbs of the fetus after birth or induction of labor .Results There were 99 cases of fetal limb deformities in 41 ,460 pregnancy ,of which 31 cases of femoral abnormalities were found by routine ultrasound ,92 cases of fetal limb deformities were found by SCSA .68 cases of fetal limb deformities were detected by SCSA in 19- <27 weeks of gestation ,accounting for 73 .91% of detection limb deformi-ties .In the 99 cases of fetal limb deformities ,varus feet were the most was (27 cases) ,followed by short limbs deformity (24 cases) , limbs compound malformations(11 cases) ,limb posture abnormalities(10 cases) ,part of the amputation(10 cases) and multiple fin-gers/toes(7 cases) .Conclusion SCSA with color doppler ultrasonography is an effective method for prenata screening of fetal limb deformities .

To study the protective mechanism of Dusuqing Granule, a compound Chinese herbal medicine, on the senile multiple organ injury caused by bacterial pneumonia by observing the expression changes of molecules related to toll-like receptor 4 (TLR4) signaling.

Betacoronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Single-Cell Analysis