Objective To develop a system failure recovery programs in order to prevent an accident of the hospital computer network system. Methods The network failure was divided into three grades according to its influence. The groups of network malfunction was set up and can immediately start the established program, take effective measures to prevent the situation expand and spread in the event of unforeseen circumstances. Results Through the emergency power supply program, the network route emergency program, cable emergency support program and sector emergency plan, the hospital information systems run normally. Conclusion The issue of large-area network information paralysis is effectively solved and improves the information technology capacity of the hospital.

Objective:To retrospectively analyze the clinical characteristics of 193 Chinese patients with McCune-Albright syndrome (MAS).Methods:By using keywords " McCune-Albright syndrome", " Albright syndrome", or " fibrous dysplasia " as the search terms, 193 cases of MAS reported in China from January 1990 to November 2022 from the Wanfang data, CNKI, VIP, PubMed, and Embase databases were obtained, and their clinical data was retrospectively analyzed. Intergroup comparisons were carried out by using t test, Mann-Whitney U test, and χ2 test. Results:The 193 MAS patients had included 42 males and 151 females, with the median first-visit age of females being younger than males. The typical triad group had accounted for 46.1% of patients, and the middle first-visit and diagnosis age was younger than the atypical group. The primary reason for first-visit in males of MAS was fibrous dysplasia (FD), whilst that in females of MAS was peripheral precocious puberty (PPP). FD has occurred in 84.5% of the patients, with an average age of onset age being 6.1 years old, and 90% was ≤ 16 years of age. Endocrine hyperfunction was found in 79.3% of the patients, with a higher proportion in females compared with males ( P<0.05). Pituitary involvement was seen in 21.8% of the patients, and the incidence of craniofacial FD and cranial nerve compression was significantly higher in those with elevated growth hormone (GH) than without ( P<0.05). Café-au-Lait Spots were noted in 86.5% of the patients, and 28.3% (28/99) had located on the different side of FD. Conclusion:Most MAS patients had atypical manifestations and multi-systemic involvement. It is more common and occurs earlier in females. The most common reasons for initial diagnosis in male and female patients were FD and PPP, respectively. Patients with elevated GH should be examined for cranial nerve compression.

Objectives:To compare the shon-term clinical effects of stand-alone oblique lateral interbody fu-sion(SA 0LIF)and posterior lumbar interbody fusion(PLIF)in the treatment of degree Ⅰ single-segment degen-erative lumbar spondylolisthesis.Methods:The data of 80 patients with degree Ⅰ single-segment degenerative lumbar spondylolisthesis who met with the inclusion criteria of this study between March 2019 and August 2021 were retrospectively analyzed.The patients were divided into the SA 0LIF group(38 cases)and PLIF group(42 cases).The intraoperative blood loss,operative time,postoperative drainage volume,postoperative am-bulation time,postoperative length of hospital stay,and complication rate were compared between the two groups of patients.The disc height(DH),foraminal height(FH),spondylolisthesis angle(SA),and fusion rate(FR)were measured before and after surgery and during follow-up.The visual analogue scale(VAS)and 0swestry disability index(ODI)were used to evaluate the short-term clinical efficacy.Results:The intraoperative blood loss(61.3±21.3mL vs 123.5±22.4mL),operative time(89.8±30.1min vs 112.1±15.2min),postoperative drainage volume(44.2±23.2mL vs 163.5±22.2mL),postoperative ambulation time(2.0±1.0d vs 4.2±2.1d),postoperative hos-pital stay(5.8±3.0d vs 9.2±5.3d),and complication rate(5.3％vs 19.1％)were all less in the SA OLIF group than those in the PLIF group(P＜0.05).At 1 week postoperatively,the ODI[(19.3±6.6)％vs(30.9±8.3)％]and lower back pain VAS scores(2.3±0.5 vs 3.0±1.0)of the SA OLIF group were lower than those in the PLIF group(P＜0.05),but no statistical difference was there between the two groups at 3 months after surgery and final follow-up(P＞0.05).During postoperative follow-up,the postoperative increases of DH and FH in the SA OLIF group were higher than those in the PLIF group(P＜0.05),and there was no significant difference in SA and FR after surgery between groups(P＞0.05).Conclusions:SA OLIF and PLIF are equally safe and effective in treating degree Ⅰ single-segment degenerative lumbar spondylolisthesis,However,SA OLIF has the advantages of less surgical trauma,faster recovery,and better opening effect on the intervertebral space.

The Spt-Ada-Gcn5-acetyltransferase (SAGA) is an ancillary transcription initiation complex which is highly conserved. The ADA1 (alteration/deficiency in activation 1, also called histone H2A functional interactor 1, HFI1) is a subunit in the core module of the SAGA protein complex. ADA1 plays an important role in plant growth and development as well as stress resistance. In this paper, we performed genome-wide identification of banana ADA1 gene family members based on banana genomic data, and analyzed the basic physicochemical properties, evolutionary relationships, selection pressure, promoter cis-acting elements, and its expression profiles under biotic and abiotic stresses. The results showed that there were 10, 6, and 7 family members in Musa acuminata, Musa balbisiana and Musa itinerans. The members were all unstable and hydrophilic proteins, and only contained the conservative SAGA-Tad1 domain. Both MaADA1 and MbADA1 have interactive relationship with Sgf11 (SAGA-associated factor 11) of core module in SAGA. Phylogenetic analysis revealed that banana ADA1 gene family members could be divided into 3 classes. The evolution of ADA1 gene family members was mostly influenced by purifying selection. There were large differences among the gene structure of banana ADA1 gene family members. ADA1 gene family members contained plenty of hormonal elements. MaADA1-1 may play a prominent role in the resistance of banana to cold stress, while MaADA1 may respond to the Panama disease of banana. In conclusion, this study suggested ADA1 gene family members are highly conserved in banana, and may respond to biotic and abiotic stress.
Musa/genetics* ; Phylogeny ; Fungal Proteins ; Cell Nucleus ; Histones ; Stress, Physiological/genetics*