1.Correlation between clinical features at admission and recent prognostic outcome in patients with acute ;myocardial infarction
Huichao PAN ; Jianping LIU ; Lihua ZHANG ; Yan JIN
Chinese Journal of cardiovascular Rehabilitation Medicine 2014;23(2):131-134
Objective:To analyze the correlation betWeen clinical features at admission and recent prognostic outcome in patients With acute myocardial infarction (AMI).Methods:The data of 108 patients admitted because of primary AMI Were retrospectively analyzed.According to occurrence of major adverse cardiovascular events (MACE)or not after discharge,they Were divided into event group (n=61)and non-event group (n=47).Clinical features such as Gender,age etc.of tWo groups Were collected,analyzed and compared.After one-year folloW-up,correlations betWeen clinical feature indexes and MACE incidence Were analyzed.Results:Compared With non-event group, there Were significant increase in mean age,mean arterial pressure (MAP),left ventricular end-diastolic dimension (LVEDd),percentage of> Killip class 2,Grace score and multi-vessel coronary disease,and significant decrease in left ventricular ejection fraction (LVEF)in event group,P<0.05~<0.01. Single factor correlation analysis indi-cated that age,MAP,LVEF,percentage of > Killip class 2,Grace score and multi-vessel coronary disease rate Were correlated With MACE incidence rate (P<0.05~<0.01);multi-factor Logistic regression analysis indicated that age (OR=0.827),LVEF (OR=0.624),Grace score (OR=0.589)and multi-vessel coronary disease rate (OR=0.461)Were risk factors for MACE in AMI patients,P<0.05 all.Conclusion:Advanced age,loW left ven-tricular ejection fraction,higher Grace score and more multi-vessel coronary disease are high risk factors for recent occurrence of major adverse cardiovascular events in patients With acute myocardial infarction.
2.Interpretation of the 2024 American Heart Association Scientific Statement: evaluation and management of chronic heart failure in children and adolescents with congenital heart disease
Yuxing YUAN ; Jinpeng ZHANG ; Huichao SUN ; Bo PAN ; Jie TIAN
Chinese Journal of Applied Clinical Pediatrics 2024;39(11):824-830
Congenital heart disease (CHD) is one of the leading causes of heart failure (HF) in pediatrics.In 2024, the American Heart Association, based on existing knowledge and research findings, issued its first scientific statement on the assessment and management of HF in children and adolescents with CHD.The statement emphasizes the current lack of understanding of the epidemiology, pathophysiology, staging, and outcomes of chronic HF in pediatrics with CHD, and calls for the development of standardized definitions, monitoring protocols, and treatment strategies to improve the clinical outcomes and quality of life for this population.This article interprets the main content of the statement, aiming to provide reference and guidance for the accurate assessment and comprehensive management of chronic HF in children and adolescents with CHD.