1.Clinical application of posterior continuous curvilinear capsulorhexis of posterior capsular rupture in the phacoemulsification
International Eye Science 2015;(1):83-85
Abstract? AlM: To observe the clinical effect of posterior continuous curvilinear capsulorhexis ( PCCC ) in phacoemulsification with posterior capsular rupture.?METHODS: Thrity-eight age-related cataract patients (38 eyes) from March 2013 to October 2013 were selected as experimental group and 50 age - related cataract patients ( 50 eyes ) from March 2013 to October 2013 as control group. ln experimental group, PCCC were used in the intraoperative posterior capsule tears in phacoemulsification. And in control group phacoemulsification was applied. The visual acuity and surgical complications were compared between two groups, the follow-up period was continued to 3mo after operation.?RESULTS: The visual acuity and corneal edema in two groups had statistically significant ( P<0. 05 ) at 1d after operation. Three months after operation, the visual acuity and corneal edema in two groups was not statistically significant ( P > 0. 05 ). At 1d after operation, the intraocular pressure in two groups was not statistically significant (P>0. 05). Three months after operation, the pupil and cystoid macular edema, retinal detachment in two groups was not statistically significant (P>0. 05).?CONCLUSlON:PCCC can improve the therapeutic effect and prevent surgical complications for phacoemulsification with posterior capsular rupture.
2.Prevention and therapy of atherosclerosis in childhood.
Yong-Hui YU ; Yao CHEN ; Yi WANG
Chinese Journal of Pediatrics 2005;43(7):547-550
Adolescent
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Atherosclerosis
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drug therapy
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etiology
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prevention & control
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therapy
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Child
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Humans
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Hyperlipidemias
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complications
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prevention & control
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therapy
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Hypolipidemic Agents
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therapeutic use
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Life Style
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Obesity
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complications
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prevention & control
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Primary Prevention
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Risk Factors
4.Interleukin-8 and tumor necrosis factor-? are contributing to airw ay inflammation in rat model of chronic obstructive pulmonary disease
Yong ZHANG ; Deyun CHENG ; Hui WANG
Chinese Journal of Respiratory and Critical Care Medicine 2003;0(06):-
Objective To explore the role of interleukin-8(IL-8) in the pathogene sis of COPD MethodsRat model of chronic obstructive pulmonary disease(COPD) was established by exposure Wistar rats to cigarette smoke dai ly for 120 days Total cell counts and neutrophil counts in BALF were examined The levels of IL-8 and tumor necrosis factor-?(TNF-?) in BALF and serum wer e measured with ELISA Lung tissue section stained by HE was observed to study t he morphological alternations and MLI,MAN and PAA were measured Result sMLI and PAA in COPD rat were higher than those in control group (P
5.Biological features of osteoblasts isolated from patients with type Ⅰ neurofibromatosis
Hui CHEN ; Yong QIU ; Bin WANG
Chinese Journal of Orthopaedics 2001;0(05):-
Objective To detect the neurofibromin expression and observe the biological features of the osteoblasts of patients with type 1 neurofibromatosis and scoliosis. Methods 10 cases of congenital scoliosis and 8 cases of NF1 scoliosis were chosen. The two groups were with the similar age(with the average of 11.7 years and 12.5 years) and Cobb angle(with the average of 85? and 94?). Cancellous bone was harvested from the ilia and the bone explants culture system was used. Proliferation of the osteoblasts, and also the specific differentiation index including alkaline phosphatase, type Ⅰ collagen and osteocalcin was assayed in sewnd generation osteoblasts. Neurofibromin expression in the two kinds of osteoblasts was detected with immunoprecipitation followed by Western blot. Results Compared to the osteoblasts of patients with congenital scoliosis, lower level of neurofibromin was expressed in osteoblasts of patients with NF1 scoliosis, (the OD value was 1.05?0.06 and 2.59?1.40 respectively, P=0.002). The level of alkaline phosphatase, type Ⅰ collagen and osteocalcin were significant lower in osteoblasts of patients with NF1 scoliosis than those of CS patients (44.69 IU/mg vs 51.38 IU/mg, P=0.019; 226.34 ng/mg vs 249.93 ng/mg, P=0.014; 7.41 ng/mg vs 8.87 ng/mg, P=0.049). But the proliferation rate of the NF1 osteoblasts was significant higher than that of the CS osteoblasts (3.34 and 2.70 respectively, P=0.049). Conclusion With the decrease of neurofibromin expression, the NF1 osteoblasts show some defects in their function, these function defects may contribute to varieties of skeletal abnormalities as dystrophic change and decreased bone density.
6.Clinical study on all capsule polishing mode for decreasing the occurrence of posterior capsular opacification
Hui, NA ; Yong, WANG ; Da-Guang, BI
International Eye Science 2014;(6):1143-1144
AIM:To evaluate the effect of all capsule polishing with polishing mode for decreasing the occurrence of posterior capsular opacification( PCO) .
METHODS: Totally 194 eyes ( 162 patients ) were performed phacoemulsification, posterior chamber intraocular lens were implanted. One hundred eyes were performed with all capsule polishing with polishing mode;94 eyes were performed with the polishing apparatus.
RESULTS:The patients were followed up for 12mo. Six eyes ( 6. 0%) of PCO were found in the 100 eyes with polishing mode group; 15 eyes ( 16. 0%) of PCO were found in the 94 eyes with the polishing apparatus group. The difference was significant (P<0. 05).
CONCLUSION: It can decrease the occurrence of PCO by performing all capsule polishing with polishing mode.
7.Clinical features and multimodality treatment of 11 cases with small-cell esophageal carcinoma
Hui ZHANG ; Hua-Yong WANG ; Liang-Jun WANG ; Al ET
China Oncology 2001;0(05):-
Purpose:To investigate the clinical feature of small-cell esophageal carcinoma,and try to find rational combined therapy modality.Methods:A retrospective study was conducted in a total of 11 cases of small cell esophageal carcinoma hospitalized from 1990 to 1999 and the literature of small cell esophageal carcinoma in recent years were re- viewed.Results:The median survival time of these patients is 11 months,five cases survived over 1 year,the 1 yr survival rate is 45.45%;only one patient survived over 3 years;nine cases received multimodality treatment,the median survival time was 12 months,and of which,the median survival time of the seven patients treated with combined regimens including surgical operation was 15 months,and the survival time was 10 months and 7 months respectively in two patients treated with combined regimens not including surgical operation.one patient underwent surgery alone,the survival time was 5 months;one patient received chemotherapy alone and survived 6 months.Conclusions:Small cell esophageal carcinoma has a poor prognosis.multimodality treatment including chemotherapy is an effective approach in improving survival;surgical operation play an important role which can not be replaced and preoperative chemotherapy combined with surgical resection and postoperative chemotherapy may be a better combined treatment modality in local regional small cell carcinoma of e- sophagus.
8.Pracice and Exploration of Open-laboratory in Pathophysiology
Yong CUI ; Wendan YUAN ; Hui WANG ; Weichen WANG ; Hongjing CAI
Chinese Journal of Medical Education Research 2006;0(10):-
From September of 2006,Department of Pathophysiology opened laboratory to the undergraduates of 2004 grade.Stu- dents chose titles and designed experiments by themselves,and after expert teachers' assessment,they put them into practice. Functional Laboratory of the college is in charge of the oprtation and administration of it.Through this semester's practice and exploration,we got satisfactory effect and great welcome from students.
10.An empirical study of skill points in pathology courses
Zhenmin GUAN ; Jing LI ; Hui WANG ; Yong LU ; Junmei CHENG
Chinese Journal of Medical Education Research 2013;(5):536-540
Objective To investigate the characteristics and distribution of class teaching skill points in state high quality course pathology using Flanders interaction analysis system to analyze the teaching video of pathology course.Methods Teaching videos of state high quality course (pathology course) between 2006 and 2012 were analyzed by Flanders interaction analysis system.Frequencies of using teaching skill,presentation skill and interaction skill were statistically analyzed.Results The study found that frequencies of using teaching skill points in pathology course were decreased in the following order:presentation skill (53.94%),interaction skill (26.64%) and teaching skill (19.42%).Sensory focusing was most commonly used in presentation skill.Monitoring and expressing concern were most commonly used in interaction skill.Gestures and cases were most commonly used in teaching skill.Conclusions Teachers in pathology teaching should correctly handle the relationship among the presentation,interaction and teaching skills according to the teaching objectives and teaching content.