1.The Regulation Factors of the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
Yan HUANG ; Ying-Hui LI ;
China Biotechnology 2006;0(05):-
Disuse-related osteopenia is mainly due to decrease of bone formation which relates closely to the changes of osteoblast function and differentiation. Bone marrow mesenchymal stem cells which are multipotent cells present in bone marrow can differentiate into osteoblast. The factors which regulate the osteogenic differentiation of bone marrow mesenchymal stem cells were introduced. This will increase the understanding and aid in the prevention and treatments of bone loss to create a healthier life for astronauts and patients after disuse.
4.Experimental study on expression of osteopontin in viral myocarditis.
Fang-ying YIN ; Jing-hui SUN ; Yan-yan HAN
Chinese Journal of Pediatrics 2008;46(9):710-711
Animals
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Male
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Mice
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Mice, Inbred BALB C
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Myocarditis
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metabolism
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virology
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Myocardium
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metabolism
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Osteopontin
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metabolism
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Virus Diseases
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metabolism
5.Clinical features of patients with metastasis in phalanges as first symptom of primary lung cancer.
Jun-qing HAN ; Chun-yan HAN ; Ying-hui BI
Chinese Journal of Oncology 2007;29(7):534-535
Adenocarcinoma
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secondary
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therapy
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Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Bone Neoplasms
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secondary
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therapy
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Carcinoma, Squamous Cell
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secondary
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therapy
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Cisplatin
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administration & dosage
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Combined Modality Therapy
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Cyclophosphamide
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administration & dosage
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Doxorubicin
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administration & dosage
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analogs & derivatives
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Finger Phalanges
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surgery
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Follow-Up Studies
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Humans
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Ifosfamide
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administration & dosage
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Lung Neoplasms
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pathology
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therapy
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Male
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Middle Aged
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Radiotherapy, Conformal
6.Blueberry muffin in 2 neonates.
Hui WU ; Guo-Hua WANG ; Chao-Ying YAN
Chinese Journal of Contemporary Pediatrics 2011;13(7):600-601
7.Protective effect of physcione on acute liver injury in rats
Li-Yan ZHANG ; Wen-Hui SU ; Ying XIONG ; Dan WANG ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To investigate the protective effect of physcione on acute liver injury in rats.Methods Acute liver injury rat model was constructed with 2ml/kg CCl_4((?)3 d)via intragastric administration.The serum concentrations of alanine aminotransferase(ALT),aspartate aminotransferase(AST)and tumor necrosis factor (TNF)in different groups were detected.Hepatic histopathology of different groups was also observed to reflect the effect of physcione.Results The serum concentrations of ALT,AST and TNF in physcione group were significantly lower than those of model group(P
9.Study on excretion of 20 (S) -protopanaxadiolocotillol type epimers in rats.
Xiang-Meng WU ; Li WANG ; Ying-Ying NI ; Hui WANG ; Wen-Yan WANG ; Qing-Guo MENG
China Journal of Chinese Materia Medica 2014;39(7):1306-1310
Gindenosides are the active ingredients of Panax ginseng. 20 (S) -protopanaxadiolocotillol type epimers are the main metabolites of 20 (S) -protopanaxadiol. The previous studies showed that there are stereoselectivity difference in pharmacodynamics and pharmacokinetics between 24R-epimer and 24S-epimer. The purpose of this study was to explore the excretion of the epimers in bile, feces and urine of rat. Liquid chromatography tandem mass spectrometry method has been performed for determination of 24R-epimer and 24S-epimer in bile, feces and urine. 24R-epimer or 24S-epimer was intragastric administered to rats at a single dose of 10 mg x kg(-1). Results showed that after administration the recovery of 24R-epimer and 24S-epimer in feces was 17.69% and 17.09%, respectively, while both of the two epimers were hardly detected in urine. The 48 h cumulative biliary excretion rate of 24R-epimer was 8.01% after administration, while only 1.47% for 24S-epimer. It indicated that there are stereoselectivity in biliary excretion of the epimers with intragastric administration.
Animals
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Bile
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chemistry
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metabolism
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Drugs, Chinese Herbal
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chemistry
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pharmacokinetics
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Feces
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chemistry
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Ginsenosides
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chemistry
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pharmacokinetics
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Male
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Mass Spectrometry
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Panax
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chemistry
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Rats
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Rats, Sprague-Dawley
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Stereoisomerism
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Urine
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chemistry
10.Effects of tree species on polysaccharides content of epiphytic Dendrobium officinale.
Ying-Ying GUO ; Yan ZHU ; Jin-Ping SI ; Jing-Jing LIU ; Cheng-Yong WU ; Hui LI
China Journal of Chinese Materia Medica 2014;39(21):4222-4224
To reveals the effects of tree species on polysaccharides content of epiphytic Dendrobium officinale. The polysaccharides content of D. officinale attached to living tress in wild or stumps in bionic-facility was determined by phenol-sulfuric acid method. There were extremely significant differences of polysaccharides content of D. officinale attached to different tree species, but the differences had no relationship with the form and nutrition of barks. The polysaccharides content of D. officinale mainly affected by the light intensity of environment, so reasonable illumination favored the accumulation of polysaccharides. Various polysaccharides content of D. officinal from different attached trees is due to the difference of light regulation, but not the form and nutrition of barks.
Dendrobium
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chemistry
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Light
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Plant Bark
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physiology
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Polysaccharides
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analysis
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Trees