4.Report of a case with Schwardz-Jampel syndrome.
Rong QIANG ; Hui-ping SHI ; Wei YU
Chinese Journal of Pediatrics 2003;41(6):456-456
Child
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Humans
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Karyotyping
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Male
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Osteochondrodysplasias
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classification
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diagnosis
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genetics
7.Metatropic dwarfism in a case.
Ji HUANG ; Li-fu GUAN ; Hui-ping SHI ; Wei YU
Chinese Journal of Pediatrics 2003;41(4):310-310
8.Chemical constituents from traditional Chinese medicine Siegesbeckia pubescens.
Rui WANG ; Yan-ping SHI ; Qing-zhong WANG ; Hui CAO
China Journal of Chinese Materia Medica 2014;39(24):4811-4815
Column chromatography on silica gel was used to study the chemical constituents of traditional Chinese medicine Siegesbeckia pubescens. The chemical structures of the separated compounds were elucidated by spectroscopic data analyses. As a result, eighteen compounds were obtained and identified as 3, 4'-dimethoxy quercetin(1), 3, 3', 4'-trimethoxy quercetin(2), 3, 3'-dimethoxy quercetin(3), 7, 3', 4'-trimethoxy luteolin(4), ursolic acid(5), 2β,19α-dihydroxyursolic acid(6), 2β-hydroxyursolic acid (7), stigmasterol-7-one(8), 5α, 8α-epidioxy-24(R)-methyl-cholesta-6, 22-diene-3β-ol(9), β-sitosterol(10), 2, 6-di(3-hydroxy-4-methoxyphenyl)-3, 7-dioxacyclo [3. 3. 0] octane (11), aurantiamide acetate (12), 3-(m-hydroxyl-p-methoxy)-N-(2'-p-hydroxyl-phenethyl)-2E-acrylamide(13), p-hydroxy benzaldehyde (14), m-hydroxy-p-methoxy benzaldehyde (15), 3, 4, 5-trimethoxybenzoic acid(16), monoethyl malonate(17), and p-hydroxylcinnamic acid(18). Among them, compounds 1-9, 11-18 were isolated from this plant for the first time.
Asteraceae
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chemistry
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Drugs, Chinese Herbal
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chemistry
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isolation & purification
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Luteolin
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chemistry
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isolation & purification
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Medicine, Chinese Traditional
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Plants, Medicinal
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Quercetin
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chemistry
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isolation & purification
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Sitosterols
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chemistry
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isolation & purification
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Triterpenes
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chemistry
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isolation & purification
10.The significance of changes in thyrotropin receptor antibody and soluble intercellular adhesion molecule-1 levels in patients with thyroid-associated ophthalmopathy during intravenous methylprednisolone pulse treatment
Ping FAN ; Bingyin SHI ; Hui GUO ; Li XU
Chinese Journal of Endocrinology and Metabolism 2010;26(10):859-862
Objective To explore the relationship of thyrotropin receptor antibody (TRAb) and soluble intercellular adhesion molecule-1 ( sICAM-1 ) in patients with thyroid-associated ophthalmopathy ( TAO), and the role played by TRAb and sICAM-1 in the pathogenesis of TAO. Method Twenty-three TAO patients were assigned to groups according to the clinical activity score and EUGOGO. All patients were treated with intravenous methylprednisolone pulse. The levels of serum TRAb and sICAM-1 were evaluated by a competitive radioimmunoassay and enzyme-linked immunosorbent assay respectively before treatment and by the end of each methylprednisolone pulse. Results The differernce in serum TRAb levels was associated with activity scores of TAO (P=0. 020). The change in serum sICAM-1 was associated with durations of TAO ( P = 0.015). During methylprednisolone treatment in active TAO patients, the levels of TRAb kept on decreasing gradually and markedly declined after the third methylprednisolone pulse in active TAO patients (P<0.05). The trends of changes in serum TRAb and sICAM-1 levels were both different in active and inactive TAO patients by tendency analysis. Conclusion TRAb level was related to the activity of TAO and might serve as a significant predictor of response to methylprednisolone therapy. The negative correlation between sICAM-1 levels and duration of TAO corroborates the role played by ICAM-1 during the early stage of TAO. Higher sICAM-1 levels are not expected to be specific to TAO and may not predict a response to methylprednisolone therapy.