1.The improvement of archives system for medical equipment management
China Medical Equipment 2014;(7):86-87
Objective: To improve the database of medical equipment archives system and manage medical equipment more scientifically and efficiently. Methods:According to the needs of medical equipment management, the problems of medical equipment archives system would be analyzed and addressed. Results:In recent medical equipment archives system, the database of usage rate, cost-effectiveness, maintenance costs and property management should be improved. Conclusion:The improved archives system could provide reliable basic data and multi-faceted sharing for medical equipment dynamic management.
2.Determination of serum prealbumin and C-reactive protein in 68 burn patients and its clinical significance
Hui CHEN ; Yingchun ZHOU ; Ping GUAN
International Journal of Laboratory Medicine 2008;29(5):416-417
Objective To investigate the change of serum prealbumin (PA) and C-reactive protein (CRP) in burn patients and its clinical significance.Methods Sixty eight cases of burn patients were divided into two groups,group Ⅰ [n=38,with total burn surface area less than 15% of total body surface area (TBSA)] and groupⅡ(n=30,with total burn surface area more than 50% of TBSA). Thirty healthy people were set as healthy control group. Particle enhanced immunoturbidimetic assay was applied to detecting the serum levels of PA and CRP for all subjects on the day 1 after burns.Results The CRP level was much higher and serum level of PA was much lower in group Ⅱ than that of group Ⅰ,respectively. There existed significant negative correlation between PA and CRP level.Conclusion The level of serum PA decreases significantly along with total burn surface area expansion. PA can be used as a sensitive marker for estimation of inflammation degree after burns.
3.Research on some sero-enzymes measurement by applying three different vacuum tubes for venous blood samples
Hui CHEN ; Yingchun ZHOU ; Ping GUAN
International Journal of Laboratory Medicine 2008;29(7):586-587,591
Objective To discuss the comparability of ALT, AST, CK and LDH results by ap- plying three different vacuum tubes (no additive tubes, separation gel coagulation promoting tubes and other coagulation promoting tubes) for venous blood samples, and to provide evidence for clinical tests. Methods Fast venous blood from 26 healthy blood donors were collected in test tubes without additives, separation gel coagulation promoting tubes and other coagulation promoting tubes. Olympus AU5400 Biochemical Analyzer was applied to examining serum ALT, AST, CK and LDH for all pre- pared serum samples. Results There was no statistical difference of serum ALT, AST, CK and LDH level collected in test tubes without additives, separation gel coagulation promoting tubes and other co- agulation promoting tubes. With the no additive tubes as the standard tubes, the above result bias be- tween separation gel coagulation promoting tubes and other coagulation promoting tubes were clinically acceptable. Conclusion There is credible comparability of serum ALT, AST, CK and LDH level a- mong different kinds of venous blood samples collected in test tubes without additives, separation gel coagulation promoting tubes and other coagulation promoting tubes. The separation gel coagulation promoting tubes and other coagulation promoting tubes can substitute test tubes without additives for ALT, AsT, CK and LDH determination.
4.Effects of calcitonin gene-related peptide on osteoprotegerin and RANKL expressions in osteoblast cells in bone metastasis microenvironment of breast cancer in vitro
Chen YANG ; Hui ZHAO ; Yang YAO ; Zhiyu WANG ; Ping CHEN
Chinese Journal of Cancer Biotherapy 1995;0(03):-
Objective:To observe the effect of calcitonin gene-related peptide (CGRP) on the expression of osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand (RANKL) in osteoblast cells through an in vitro breast cancer cell and osteoblast cell co-culture system. Methods:The metastatic breast cancer MDA-MB-231 or MDA-MB-435 cells were co-cultured with osteoblast MG63 cells to establish an in vitro microenvironment of bone metastasis of breast cancer. After treated with CGRP(1?108 mol/L),OPG and RANKL mRNA and protein expressions in osteoblast MG63 cells were examined by RT-PCR and Western blotting. Results:Expression of RANKL in osteoblast MG63 cells was up-regulated at both mRNA and protein levels when osteoblast MG63 cells were co-cultured with breast cancer MDA-MB-231 or MDA-MB-435 cells,while those of OPG in osteoblast MG63 cells were both down-regulated (P
5.Fibrosis-related differential expression and upstream mechanisms of beta-arrestin in the carbon tetrachloride-induced liver fibrosis mouse model.
Hui-ling SUN ; Yu-li GE ; Yong-ping CHEN
Chinese Journal of Hepatology 2013;21(10):773-775
Animals
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Arrestins
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metabolism
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Liver
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pathology
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Liver Cirrhosis, Experimental
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metabolism
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pathology
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Male
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Mice
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Mice, Inbred ICR
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beta-Arrestins
7.Reform practice of medical statistics teaching for medical doctoral students
Hui CHEN ; Tong ZOU ; Jing DU ; Ping WU ; Binrong MA
Chinese Journal of Medical Education Research 2011;10(2):144-146
Aiming at the cultivation goal and requirements as well as the current status of learning and applying medical statistics for medical doctoral students, a new idea of medical statistics teaching for medical doctoral students that combined theory with practice, science research and paper writing was proposed, with respect to improving the teaching content, teaching with clinical cases, enhancing the teaching material development, paying attention to the computer practice, and providing the writing standard for research papers.
8.Relationship between plasma level of fibrinogen and carotid atherosclerosis in the patients with ischemic cerebrovascular disease
Ping QV ; Hui HUANG ; Qiong ZHANG ; Guihai CHEN
Chinese Journal of Neurology 2008;41(6):367-370
Objective To investigate the association between the plasma level of fibrinogen and carotid atherosclerosis(CAS)in patients with ischemic cerebrevascddar disease(ICVD),and the effects intensity of different risk factors on CAS.Methods Carotid intima-media thickness(IMT)was measured by color Doppler uhrasonography in 840 patients with ICVD,including cerebral infarction(ci),transient ischemic attack and insufficient blood-supply of vertebral-basilar artery.According to the results of uhrasonography,the patients were divided into four groups:normal(IMT≤0.9 mm),arterial sclerosis (0.9 mm