1.Analysis of the clinical effects of thymosin ?1 on gastrointestinal carcinoma in elderly patients
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
Objective To observe and evaluate the clinical effects of thymosin ?1 on gastrointestinal carcinoma in elderly patients.Methods Ninety-six aged patients with gastrointestinal carcinoma in the General Hospital of PLA,who had received chemotherapy,were randomly divided into two groups(n=48 for each group): control group and treatment group.Patients in the treatment group received thymosin ?1 by subcutaneous injection in a dose of 1.6mg,the treatment was given once every other day and the whole course lasted for 8 weeks;while patients in the control group received physiological saline solution in the same amount only instead of thymosin.For the patients in both groups,the activities of peripheral blood T cell subsets,such as CD4+,CD4+/CD8+ and natural killer(NK),were measured by flow cytometry before the treatment and in the 2nd,4th,8th week of chemotherapy.The life quality of every patient was evaluated by Karnofsky scores at the same time.Results After the treatment,the Karnofsky scores in the treatment group were much higher than that in the control group(P
2.Student-oriented teaching and its application in teaching of Medical information retrieval and use
Jun PENG ; Zhaoyang HUI ; Hui WAN ; Lu HAO ; Min LU
Chinese Journal of Medical Library and Information Science 2014;(5):72-75
The necessity to carry out student-oriented teaching of Medical information retrieval and use course in medical postgraduate was analyzed according to its theory followed by an elaboration on its module setting, course management methods, course examination forms and teachers.
3.Surgical Treatment of Malunited and Nonunited Colles' Fracture: Report of 6 Cases
Hui Wan PARK ; Jun Seop JAHNG ; Jun Dong CHANG
The Journal of the Korean Orthopaedic Association 1985;20(6):1061-1066
Even though closed treatment of Colles' fracture leads to satisfactory clinical results, many patients who have had such a fracture are found to have permanent disability and poor function of hand and wrist. Malunion occurs frequently following Colles' fracture and there is considerable disability, pain and deformity associated with this lesion. Such deformity of wrist can usually be prevented by proper treatment, but if deformity developes, better function and a normal appearing wrist can be restored by a corrective osteotomy. The authors experienced 6 cases of malunited Colles' fracture which had been treated by corrective osteotomy, Darrach resection, and osteoclasis, etc.
Colles' Fracture
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Congenital Abnormalities
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Hand
;
Humans
;
Osteotomy
;
Wrist
4.An analysis for the clinical difference between post infectious irritable bowel syndrome and non post infectious irritable bowel syndrome
Hui SHI ; Jun WAN ; Wenhui LIU ; Binbin SU
Chinese Journal of Internal Medicine 2015;54(4):326-329
Objective To study the clinical discrepancy between patients with post infectious irritable bowel syndrome(PI-IBS) and non post infectious irritable bowel syndrome(NPI-IBS),and assess the value of serum intestinal fatty acid binding protein (I-FABP) for differential diagnosis.Methods A total of 117 patients with PI-IBS,201 patients with NPI-IBS and 31 healthy controls were prospectively recruited in General Liberation Army Hospital from 2010 to 2013.Plasma samples and clinical data were collected.Serum I-FABP level was measured by an enzyme-linked immunosorbent assay.Results The median age of patients with PI-IBS was 36 years.The median time to diagnosis in PI-IBS group was significantly longer than that in NPI-IBS group [(19.7 ± 10.3) months vs (11.4 ± 5.3) months,P < 0.05].Similarly,the proportion of anxiety [58.1% (68/117) vs 28.9% (58/201),P < 0.05] and the value of I-FABP[(42.6 ± 14.8) μg/L vs (17.3 ± 11.5) μg/L,P < 0.05] in PI-IBS group were significant higher than NPI-IBS patients.The level of I-FABP of healthy controls [(10.6 ± 8.2) μg/L] was also significantly lower than that of PI-IBS patients (P < 0.05),yet no difference from that of NPI-IBS group.The I-FABP value of subgroup PI-IBS patients with diarrhoea (IBS-D) was significant higher than that of NPI-IBS group [(54.8 ± 9.3) μg/L vs (12.3 ± 6.2) μg/L,P < 0.05].However,other parameters including gender,age,GSRS score,and I-FABP value of subgroup constipation (IBS-C) and mix (IBS-M),were not different between PI-IBS group and NPI-IBS group (all P > 0.05).Conclusion PI-IBS is an occult intestinal inflammation disease with mucosa injury.I-FABP might be a potential testing marker for the diagnosis of PI-IBS.
5.The clinical characteristics of ulcerative colitis of 525 hospital-based patients from 1994 to 2009
Hui SHI ; Jun WAN ; Long XIAO ; Qing CHANG ; Yuan GONG ; Changzheng WANG
Chinese Journal of Internal Medicine 2011;50(1):40-43
Objective To investigate the clinical characteristics and chronological change of ulcerative colitis(UC) in the Chinese PLA General Hospital in near 16 years. Methods Patients diagnosed with UC during the period from 1994 to 2009 in the Chinese PLA General Hospital were registered and their clinical profiles were analyzed. Results From 1994 to 2009, of 525 patients diagnosed with UC, with a median onset age of 42 years. The predominant form of UC was extensive colitis, which affected almost 33.3% (175/525), left-sided colitis was present in 21.3% (112/525) and rectum was present in 12.4%(65/525). The chronic relapsing type of UC was the most common (69.0%, 362/525 ), followed by the initial onset type (18. 1%, 95/525 ), chronic continuous type with intermittent exacerbations (9.7%,51/525), and acute fulminant type (3. 2%, 17/525 ). Two hundred and twenty-one patients (42. 1%,221/525) were graded as mild, 162 (30.9% , 162/525) as moderate, and 142(27.0%, 142/525) as severe UC. The proportion of mild colitis and rectum was significantly higher in patients with an onset age of over 60 years, compared with those with an onset age of less than 30 years( P <0. 05 ). The proportion of UC patients with old age onset ( P < 0. 05 ), male sex ( P < 0. 01 ), mild colitis ( P < 0. 01 ), rectum ( P <0. 01 ) , relapse-free type ( P < 0. 01 ) demonstrated a chronological increase from 1994 to 2009.Conclusions The distinctive clinical features and chronological change were seen in UC patients in recent years. Compare to those with an onset at less than 30 years, the proportion of mild colitis and rectum was significantly larger in patients with an onset at over 60 years of age, and the proportion of UC patients with old age onset, male sex, mild colitis, rectum, relapse type were less.
6.Gaucher's disease: A case report.
Hui Wan PARK ; Hyeong Mun PARK ; Jun Seop JAHNG ; Dong Eun SHIN
The Journal of the Korean Orthopaedic Association 1993;28(5):1898-1905
No abstract available.
Gaucher Disease*
8.Neurologic complications on tibial lengthening by the ilizarov technique.
Hui Wan PARK ; Jun Seop JAHNG ; Soo Bong HAHN ; Wahn Sub CHOE
The Journal of the Korean Orthopaedic Association 1993;28(6):2198-2205
No abstract available.
Ilizarov Technique*
9.Femoral lengthening and deformity correction by the ilizarov method.
Hui Wan PARK ; Jun Seop JAHNG ; Soo Bong HAHN ; Byeong Mun PARK ; Young June PARK
The Journal of the Korean Orthopaedic Association 1993;28(6):2206-2214
No abstract available.
Congenital Abnormalities*
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Ilizarov Technique*
10.Sonographic evaluation of new bone formation at the distraction site in ilizarov limb lengthening procedure.
Hui Wan PARK ; Jun Seop JAHNG ; Kyu Hyun YANG ; Ki Keun OH ; Seong Hwan MOON
The Journal of the Korean Orthopaedic Association 1992;27(1):360-368
No abstract available.
Extremities*
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Osteogenesis*
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Ultrasonography*