Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Common Cold ; prevention & control ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged

Arytenoid Cartilage ; injuries ; Humans ; Joint Dislocations ; surgery ; Laryngoscopy ; methods

Congenital heart disease and airway anomalies are correlated,and some special cardiovascular anomalies accompanying with airway anomalies like vascular tings,have a high morbidity.Congenital heart disease with airway anomalies is usually ignored in clinic.It should be considered that congenital heart disease with airway anomalies exists in children with the symptoms,such as repeated stridor,respiratory failure,difficult intubation or failure of postoperative ventilator weaning.Multidetector helical CT and bronchoscopy are important for making early diagnosis and guiding management for congenital heart disease with airway anomalies.The choice of therapeutic approaches depends on the type of airway anomalies,location and degree of the lesion.

Acute cerebral infarction needs a fast and effective imaging examination to help determine the diagnosis,analyze the causes,guide the treatment,and determine the prognosis.Multimodal CT examination obtains a wide range of reformation in a single scan,including anatomy,hemodynamics and etiology,and provides objective imaging evidence for comprehensive evaluation and appropriate treatment of cerebral infarction.This article reviews the application of this technology in acute cerebral infarction.

OBJECTIVE: To establish the quality standard of Guanxinjing capsule. METHODS:Ligusticum chuanxiong, Borneolum Syntheticum, Radix Paeoniae Rubra, Panax ginseng and Panax notogiseng were identified qualititively by TLC. The content of Protocatechuic aldehyde in salvia miltiorrhiza was determined by HPLC. RESULTS: The TLC spots were distinct and well-separated. The average recovery of the added sample was 99.91% and RSD was 1.56%. CONCLUSION: The established standard is suitable for the quality control of Guanxinjing capsule.

OBJECTIVE:To optimize the coating technology of modified release film of budesonide colonic localization tablet. METHODS: The effect of the coating parameters such as spray gun position, spraying rate, spraying atomization pressure, intake air temperature and flow, temperature of tablet bed on the microporous semipermeable film and the enteric film of localization tablet were investigated, respectively. RESULTS: The distance between spray gun muzzle and tablet bed was established as 10～20 cm; the spraying rates of the microporous semipermeable film and the enteric film of localization tablet were 3 and 1 mL?min-1, respectively, with their spraying atomization pressure at 2 and 1.5 bar(1 bar=105 Pa), intake air temperature at 50～55 ℃ and 40～45 ℃, temperature of tablet bed at (40?1) ℃ and (30?1) ℃, flow rate of intake air at 5 and 7 m3?min-1 respectively. The weight of the optimized localization tablet after being coated with semipermeable film and enteric film increased by 10% and 5%, respectively. The cumulative drug release within 24 h reached (77.5?8.6)% and the lag time was (6.0?0.5) h. CONCLUSIONS: The optimized coating technology is suitable for the preparation of modified film of budesonide colonic localization tablet.

PBL and CTM integration method is a kind of heuristic education mode of regarding student as the center of education.In order to explore the application result of this teaching method in the curriculum of nursing ethics laws and regulations,we put this mode into practice and regard nursing students as research objects.Questionnaire investigation and paper test are applied to evaluate the teaching effect.The study result shows that PBL and CTM integration method is certainly a well-established method to enhance teaching quality in the curriculum of nursing ethics laws and regulations.

Objective To analyze clinical features of papillary thyroid microcarcinoma(PTMC) and to evaluate the diagnosis and treatment for PTMC.Methods The clinical data of 447 cases of PTMC receiving surgical treatment and confirmed by pathology were reviewed.Color Doppler ultrasonography was used to identify thyroid nodules and cervical lymph nodes,and frozen section was used to confirm the pathological diagnosis during operation.104 cases received unilateral lobectomy,22 cases received unilateral lobectomy plus isthmectomy,321 cases received total thyroidectomy,257 cases underwent central neck dissection,and 54 cases underwent lateral neck dissection(level Ⅵ included).All cases took levothyroxine to maintain low TSH level after operation,and were followed up through telephone or in out-patient clinic.Results Central compartment node metastasis was found in 144 patients,and lateral neck metastasis was found in 41 cN1 cases.The age,extra-capsular invasion and multifocal carcinoma were independent risk factors of PTMC.The number of positive nodes in level Ⅵ was positively correlated with the risk of lateral node metastasis.395 cases were followed-up successfully for 20 to 42 months,with the media follow-up of 32 months.During the follow-up,recurrence or metastasis was found in 15 cases,and no death happened.Conclusions PTMC has no specific symptoms,and was difficult to be diagnosed before operation.Physical examination and color Doppler ultrasonography should be used as routine examination.Thyroid lobectomy and total thyroidectomy plus central node dissection should be major surgical treatment for PTMC patients.Lateral neck dissection should be considered in all cN1 patients.

China ; Evidence-Based Medicine ; methods ; Humans ; Orthopedics ; methods

Objective To investigate the clinical characteristics of non-motor symptoms ( NMS) in early stage newly diagnosed Parkinson 's disease ( PD) patients in different age group and different subtypes .Methods Total 96 newly diagnosed PD patients without taking any drugs and 102 normal controls were collected in outpatient visits , and their clinic information and related scales were evaluated and compared .Results Ninety-one(93.83%) PD patients had at least one NMS, common symptoms were, in order, recent memory (70.83%,68 cases)、constipation (48.96%,47 cases)、attention dysfunction (47.92%,46 cases), and they were significantly higher than PD group (all P<0.01).The incidence of anxiety and panic in patients≤60 years old was significantly higher than that in patients>60 years old (P<0.01).The incidence of urgency in rigidity type was significantly higher than in tremor type(P<0.01).Conclusions NMS in patients with newly diagnosed PD are complex and diverse .The performance in different age groups and different clinical subtypes are also different .