1.Clinical application of solution focused approach in the functional gastrointestinal disorders
Chinese Journal of Practical Nursing 2009;25(34):8-11
Objective To application of solution focused approach in the functional gastrointestinal disorders.Methods 64 hospitalized clients with functional gastrointestinal disorders were randomly divided into the observation group and the control group with 32 cases in each group.We applied the normal nursing intervention to the control group,while applied the solution focused approach to the observation group.The anxiety and depression score,score of coping way and gastrointestinal symptoms were evaluated using t test.Results The scores of anxiety and depression,coping way and gastrointestinal symptoms were better in the observation group than those in the control group.Conclusions Adoption of solution focused approach can relieve FGID sufferers'negative emotion,such as anxiety and depression,increase sufferers' coping capacity and symptoms,which demonstrate pivotal significance for rehabilitation of functional gastrointestinal disorders.
2.Determination of Ephedrine Hydrochloride in Zhike Pingchuan Tangjiang by HPLC
Xin-Hui GUO ; Fen WANG ; Jun-An CAI ;
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(11):-
Objective To establish the method for detemining the content of ephedrine hydrochloride in Zhike Pingchuan Tangjiang by HPLC. Methods Diamonsil ODS1 C_(18) Column was used with acetonitrile -0.1% phosphoric solution (with 0.1% triehylamine) (3 : 97) as the mobile phase, the detection wavelength as 205 nm, and flow rate was 1.0 mL/min. Results The calibration curve was linear at the range of 0.12~ 0.96 ?g for ephedrine hydrochloride and linear equation was Y= 109759X+3792.8, r=0.9998. The average recovery was 98.4% and RSD was 0.87% (n =5). Conclusion This method was simple, accurate and proper, with good reproducibility. It can be used for quantitative analysis of ephedrine hydrochloride in Zhike Pingchuan Tangjiang.
3.Pracice and Exploration of Open-laboratory in Pathophysiology
Yong CUI ; Wendan YUAN ; Hui WANG ; Weichen WANG ; Hongjing CAI
Chinese Journal of Medical Education Research 2006;0(10):-
From September of 2006,Department of Pathophysiology opened laboratory to the undergraduates of 2004 grade.Stu- dents chose titles and designed experiments by themselves,and after expert teachers' assessment,they put them into practice. Functional Laboratory of the college is in charge of the oprtation and administration of it.Through this semester's practice and exploration,we got satisfactory effect and great welcome from students.
5.Application of LVIS stent-assisted coil embolization in intracranial wide-neck small aneurysms:clinical analysis of 32 cases
Liming QIU ; Yingbiao HONG ; Jiebo CAI ; Zhenshan WANG ; Hui PENG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(14):2110-2113
Objective To discuss the application effect of LVIS stent-assisted coil embolization in intracranial wide-neck small aneurysms.Methods The clinical data of 32 patients with intracranial wide-neck small aneurysms treated with stent-assisted coil embolization were analyzed retrospectively and evaluated.Results In 32 cases,the embolization grade was Raymond Ⅰ in 23 cases,Raymond grade Ⅱ in 7 cases,and Raymond Ⅲ in 2 cases.The successful embolization rate was 93.8%.No aneurysm was ruptured during embolization.One patient had thrombotic event in the surgery,but the occluded artery was recanalized after the treatment of immediate thrombolysis.Disorder of contralateral limb's activity and confusion were appeared in two patients after surgery.The symptoms improved by giving clopidogrel,aspirin and increasing the dosage of nimodipine.All the survival patients recovered well after 6 months of follow-up.No recurrence of aneurysm was confirmed by DSA and parent artery was patent.Conclusion Lvis stent is simple to be operated and has various models,suitable for most intracranial aneurysms,showing good performance.It suits embolization therapy in intracranial wide-neck small aneurysms,but the strong thrombosis should be valued.
6.Nursing of Cancerous Aching in Patients Receiving Whole Body Hyperthermia
Yongjun SHAO ; Shuhua CAI ; Hui FANG ; Yuling WANG
Chinese Medical Equipment Journal 2004;0(07):-
Objective To investigate the nursing of cancerous aching in patients during whole body hyperthermia. Methods Seventy patients with malignant tumors were carefully concerned before and after receiving whole body hyperthermia and their responses were recorded. Results The remission rate of aching was 88.55%, and the common side effects were burning of skin, bedsore, and nausea or vomiting. Conclusion The whole body hyperthermia therapy can relieve the cancerous pain, and good nursing can improve the efficacy.
7.Neuropsychiatric lupus:An update
Siyu SHEN ; Xiaodong FU ; Hui CAI ; Wenjian WANG
Journal of Medical Postgraduates 2003;0(08):-
This article discusses the status quo of the researches on neuropsychiatric lupus,including its pathophysiological mechanism,clinical manifestation,diagnosis,treatment and prognosis.Cerebrospinal fluid examination,electroencephalography and brain imaging could improve the sensitivity of the diagnosis of neuropsychiatric lupus.Aggressive immunosuppressive agents,high-dose corticosteroids and anticoagulants remain the key to the therapy.However,future researches should focus on the control of long-term relapse and the improvement of the quality of life.
8.Three Kinds of Antimicrobial-resistant Genes in Enterobacter cloacae
Yi GUO ; Hui JIN ; Peiquan CAI ; Chunxin WANG
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To investigate the prevalence of three kinds of antimicrobial-resistant genes in Enterobacter cloacae. METHODS Antimicrobial susceptibility test was performed by microdiluted method and antimicrobial - resistant genes were detected by PCR methods in 20 clinical strains of E. cloacae. RESULTS Twenty strains of E. cloacae showed multiple-drug resistance.Among 20 strains, the positive rates of ACT-1, DHA and TEM genes were 70.0%, 45.0% and 55.0%, respectively. The positive rates of aac(6′) -Ⅰ , ant(3″)-Ⅰ, ant(2″)-Ⅰ, aac(6′)-Ⅱ, and aac(3)-Ⅱgenes were 50.0%, 15.0%, 10.0%, 5.0% and 5.0%, respectively . The positive rates of sul Ⅰand dfrA1 genes were 50.0%, and 5.0%, respectively. But other genes were not found. CONCLUSIONS This study shows that there are multiple-drug resistance and high positive rate of three kinds of antimicrobial- resistant genes in E. cloacae isolated from our hospital.
9.Abnormal characteristics of plasma lipid levels in patients with rheumatoid arthritis
Bing HU ; Junjun WANG ; Rubing YAO ; Hui CAI ; Chunni ZHANG
Journal of Medical Postgraduates 2003;0(10):-
Objective: To explore the mechanism of high incidence of cardiovascular diseases and the levels of plasma lipids and oxidized lowdensity lipoprotein(Ox-LDL) in patients with rheumatoid arthritis(RA).Methods: Fifty-five patients with RA(24 case of active type,31 non-active) and 60 healthy controls were randomly chosen.Plasma lipids and Ox-LDL levels were studied.All the data were subjected to statistical analysis.Results: Compared with the control,total cholesterol(TC),LDL cholesterol(LDL-C) and apolipoprotein B(apoB) levels were increased in patients with active RA,while TC,triglyceride(TG),LDL-C,apoAⅠ,B and Ox-LDL levels were elevated in those with non-active RA.Furthermore,plasma lipids and Ox-LDL level decreased in the active patients as compared with the non-active ones,while only the change of apoAⅠhad statistical significance.The erythrocyte sedimentation rate was found negatively related with TC,LDL-C,high-density lipoprotein cholesterol(HDL-C) and apoAⅠ,while C-reacting protein was found negatively related with LDL-C and HDL-C.Conclusion: Ox-LDL and plasma lipid levels were changed in RA patients.Inflammation may induce changes of lipoprotein and play an important role in atherosclerosis.
10.Expression of bone morphogenetic protein-4 mRNA in the cervical posterior longitudinal ligament after decompression
Guodong CAI ; Meng SI ; Hui ZHANG ; Junqin WANG
Chinese Journal of Tissue Engineering Research 2009;13(24):4783-4786
BACKGROUND: It has been thought that posterior cervical decompression increases the risk of cervical instability and the stress on posterior longitudinal ligament may change growth factor expression in vivo. However, the association between BMP-4 expression and heterotopic bone formation has not been confirmed. Bone morphogenetic protein 4 (BMP-4) is one of factors that can lead to heterotopic bone formation alone.OBJECTIVE: To observe the effects of posterior cervical decompression on BMP-4 mRNA expression in the posterior longitudinal ligament.DESIGN, TIME AND SETTING: A randomized controlled animal experiment was performed in Taishan Medical College between January 2005 and December 2006.MATERIALS: A total of 48 adult Sprague Dawley rats of either gender and of clean grade, weighing 270-350 g, were included in this study.METHODS: All rats were randomly and evenly divided into 3 groups: experimental, sham-operated, and blank control. In the experimental group, C36 laminectomy for decompression was performed.In the sham-operated group: only skin incision was made. Rats in the blank control group received no any treatment. Four rats were allocated for each time point (1, 2, 4, and 8 weeks post-surgery) for harvesting posterior longitudinal ligament.MAIN OUTCOME MEASURES: Detection of BMP-4 mRNA expression in the cervical posterior longitudinal ligament by semi-quantitative reverse transcription-polymerase chain reaction.RESULTS: In the experimental group, obvious BMP-4 mRNA expression was found at 1-8 weeks post-surgery. While no BMP-4 mRNA expression was found at all times in the sham-operated and blank control groups.CONCLUSION: Posterior cervical decompression can increase BMP-4 mRNA expression in the posterior longitudinal ligament.Endogenous BMP-4 may contribute to ligamentous ossification and development post-surgery.