1.A new type of fusion apparatus of seaphoid-trapezium-trapezoid for limited interearpal arthrodesis
Fan LIU ; Yu-Hui CAI ;
Chinese Journal of Orthopaedic Trauma 2004;0(08):-
Objective To develop a new type fusion apparatus for scaphoid-trapezium-trapezoid (STT) arthrodesis.Methods The apparatus was designed on the basis of the anatomic data of STT measured from Chinese cadaveric wrists.Simulated arthrodeses of STT joints were conducted to test the fixation performance of the apparatus made of titanium alloy on the STT joint specimens.Several modifications were made before the apparatus was made into a finished product.Results The fusion apparatus consists of a plate and screws.The fusion plate for STT arthrodesis is made into a taper one connected to a cylinder.On the plate are three screw holes through which the three carpal bones (STT) are fixed by three screws respectively.The hollow cylinder is designed for bone grafting,and its outer threads ensure a very tight contact between the fusion plate and the carpal bones.Auxiliary tools are also made.Conclusions As the novel design of the fusion apparatus improves the mechanical strength of fixation of STT and prevents the possible rotation and collapse of fused STT,the apparatus is a reliable internal fixation device for the limited intercarpal arthrodesis.
3.Network formulaology: a new strategy for modern research of traditional Chinese medicine formulae.
Xiao-Hui FAN ; Yi-Yu CHENG ; Bo-Li ZHANG
China Journal of Chinese Materia Medica 2015;40(1):1-6
This paper briefly analyzed and discussed the current status and major scientific challenges of traditional Chinese medicine (TCM) formulaology research. To promote formulaology research, a new strategy and corresponding technology, network formulaology, were proposed to reveal the complex interaction between functional chemome and biological responses network. The research framework and directions of network formulaology were also summarized and prospected.
Chemistry, Pharmaceutical
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methods
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standards
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Drugs, Chinese Herbal
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chemistry
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Internet
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Medicine, Chinese Traditional
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standards
4.Clinical significance of iron metabolism and variation of serum Prealbumin in patients with tumor associated anemia
Min OUYANG ; Chanjuan FAN ; Hui WANG ; Qixuan BAI ; Jiufei YU
Clinical Medicine of China 2011;27(1):54-56
Objective To explore the occurrence of anemia, anaemia type, iron metabolism situation,variation of serum Prealbumin (PA), and the relationship among them in cancer patients. Methods Three hundred and seventy cancer patients, admitted from July 2007 to April 2010 to our hospital, were enrolled into the study. The clinical data of all subjects were analyzed retrospectively. Results The incidence of anemia in 370 patients was 55.67% (206/370). Among all 206 anemia cases,129 cases had mild anaemia and 77 cases had middle to severe anaemia. In the last group ( n = 77 ), we found significant decrease in serum iron level ( [ 8. 37 ± 6. 09 ] μmol/L) and increase in serum ferritin level ( [ 474. 57 ± 327. 58 ] μg/L); and the correlation between serum iron and the anemia degree( Ps < 0. 05 ). However, we found no significant differences of serum ferritin level between the groups with different degree of anemia(P >0. 05). Among all 206 anemia cases ,187(90. 77% ) patients had a low level of serum PA, but no relationship between the degree of anemia and the drop of serum PA ( P > 0. 05 ). Conclusion The anemia was very popular in cancer patients, which had correlation with iron metabolism situation but not PA.
6.Research progress of foveoschisis in pathological myopia
Yu-Ping, HE ; Hui-Juan, XIA ; Ying, FAN
International Eye Science 2015;(1):65-68
?Pathological myopia are often complicated by a series of pathological changes in fundus including foveoschisis, which can lead to visual dysfunction when processing with retinal detachment, macular hole, epiretinal membrane and vitreoretinal traction diseases. According to the current knowledge, the main mechanism of foveoschisisi might be attributed to the impaired macular structure and function caused by a variety of traction on the retinal and retina poor condition. Surgical treatments have been reported to be effective in treating foveoschisis, however, the indications and surgical procedures are still controversial. ln this article, we reviewed the clinical features, diagnosis, treatment strategies and prognosis of pathological myopia foveoschisis.
7.Analysis on strategies of tertiary public hospitals in hierarchical medical system
Yu HU ; Hui SUN ; Zhanlu XIONG ; Shaowei WU ; Man FAN
Chinese Journal of Hospital Administration 2015;(4):250-252
Hierarchical medical system is a high priority in China ’s health reform,bearing significant impacts on remolding of its healthcare system,in which tertiary public hospitals must redefine its role.Five strategies have been proposed as follows:the first is internal management;The second is high-tech;Third is paring assistance;Fourth is telemedicine;Fifth is better medical conditions.
8.Finite element model and modal analysis of CT shelter based on ANSYS
Song BAI ; Baoguo YU ; Bin FAN ; Hui DING ; Yongzhong ZHANG ; Haojun FAN ; Shike HOU
Chinese Medical Equipment Journal 2015;(9):14-16,30
To perform modal analysis of CT shelter by applying computer simulation technology so as to pro-vide theoretical guidance for CT shelter structure optimization. Based on CAD model, the finite element model of a CT shelter was established with ANSYS simulation platform. Through modal analysis, different-order modal frequency and modal shape of the shelter were computed and the kinetic characteristics were evaluated. Low order modal frequency was kept away from the natural frequency range of chassis system resonance to avoid the overall structure reso-nance; the 3rd and the 4th modal frequency and engine idle speed frequency were very close so that local resonance might occur; road roughness excitation frequency covered the first 6 order modal frequencies and the further vibration-re-ducing measures of CT equipment were suggested. Based on the theories of finite element method and current software platform, modal analysis of shelter structure can be simulated and the results can provide valuable data for the improvement of kinetic characteristics and structure design.
9.Influence of ABO-incompatible grafts in allogeneic hematopoietic stem cell transplantation
Hui FAN ; Hongli ZHU ; Xuechun LU ; Yu JING ; Honghua LI ; Li YU
Chinese Journal of Tissue Engineering Research 2007;0(03):-
0.05).CONCLUSION:Pure red cell aplastic anemia appears after allogeneic hematopoietic stem cell transplantation in major ABO incompatibility between donor and recipient,which may lead to prolonged destruction of donor-derived erythrocytes and prolonged transfusion requirements.However,myeloid and megakaryocyte hematopoietic recovery,incidence of complications and survival rate are not influenced by ABO incompatibility.
10.Diagnosis of X-Linked creatine transporter deficiency in a patient from Northeast China
Chun-Hui Hu ; Yu-Ying Fan ; Long-Fei Wang ; Tao Yu ; Xiao-Ming Wang ; Hua Wang
Neurology Asia 2015;20(2):197-201
Background: Creatine transporter (CRTR) deficiency is the most common creatine deficiency syndrome,
of which the final diagnosis relies on mutation in the X-linked CRTR gene. To date, more than 90
mutations in the SLC6A8 gene have been reported. This paper discusses a novel mutation detected via
the thorough sequencing of all the X-chromosome-specific exons investigated in a four and a half year
old boy with an intellectual disability, speech and language delay and motor disturbance. Methods:
A brain magnetic resonance imaging (MRI) and a proton magnetic resonance spectroscopy (MRS)
were carried out, the creatine and creatinine concentrations in the urine were checked and all exons
were sequenced. Results: A detailed clinical investigation revealed a reduction in the cerebral creatine
levels in the brain by the MRS, elevated creatine and creatinine concentrations in the urine and signal
abnormalities in the left frontal cortex of the brain by the MRI. A novel change was identified in the
heterozygosity of the exon 10: c.1395-c.1401 deletion.
Conclusion: The use of a combination of powerful new technologies, such as thorough exome-nextgeneration
sequencing and a brain MRS, should be considered, in order to determine any neurometabolic
diseases, especially when the signal abnormalities in the brain MRI cannot be explained by any other
factors. This mutation results most likely in a dysfunction of the creatine transport and synthesis,
hence causing central nervous system symptoms.
Carrier Proteins