1.Clinical analysis of diagnosis, treatment and bleeding pattern of 129 moderate and severe preschool hemophiliacs.
Wen-wen HE ; Run-hui WU ; Xin-yi WU
Chinese Journal of Hematology 2012;33(5):420-422
Child, Preschool
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Hemophilia A
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classification
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diagnosis
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therapy
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Hemorrhage
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diagnosis
;
therapy
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Humans
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Infant
3.Summary of Hui prescriptions for treating cough.
Wen-jin ZHANG ; Yue LIU ; Xin-hui ZHANG
China Journal of Chinese Materia Medica 2015;40(4):753-757
In this study, by using the method of literature research, 35 prescriptions related to asthma therapy has been screened out from Hui medicine through collecting the ancient and modern literature. A comparison of fragrant medicine between the name in Arab and Chinese herbal medicine is done. The countif function in Microsoft Excel 2007 is used to get the prescriptions of the drug on the frequency statistics, summarizing the common drugs of Hui medicine for asthma are Pinellia, almond, white sugar, walnut. According to the commonly used drugs, the pathogeny and treatment principle about Hui medicine for asthma is preliminarily inferred combining literature research and the related Hui medical theory. In this study, those prescriptions have been classified into 21 cases which are effective and can be used in medical therapy according to the relevant literatures with the development of the Hui people in their long process of formation of the unique diet culture, 14 useful and convenient Halal diet therapies are made up according to the indications, therapies, party name and composition. Halal diet and "medicine and food" herbs are preliminarily analyzed and summarized, which can be convenient for the people to reduce pains through the diet and improve health awareness.
Asthma
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drug therapy
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ethnology
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China
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Cough
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drug therapy
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ethnology
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Diet
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ethnology
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Drug Prescriptions
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Drugs, Chinese Herbal
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chemistry
;
therapeutic use
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Humans
;
Medicine, Chinese Traditional
4.Pathologic features of BRCA-associated ovarian carcinoma.
Chinese Journal of Pathology 2013;42(12):846-850
Age of Onset
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Cystadenocarcinoma, Serous
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genetics
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metabolism
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pathology
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Female
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Genes, BRCA1
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Genes, BRCA2
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Humans
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Immunohistochemistry
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Neoplasm Staging
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Ovarian Neoplasms
;
genetics
;
metabolism
;
pathology
;
Receptors, Progesterone
;
metabolism
;
Tumor Suppressor Protein p53
;
metabolism
5.Recent advances on ovarian epithelial cancer: definition, subtypes and pathologic features.
Chinese Journal of Pathology 2013;42(9):624-628
Adenocarcinoma, Clear Cell
;
metabolism
;
pathology
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Adenocarcinoma, Mucinous
;
metabolism
;
pathology
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Carcinoma, Endometrioid
;
metabolism
;
pathology
;
Carcinoma, Transitional Cell
;
metabolism
;
pathology
;
Cystadenocarcinoma, Serous
;
metabolism
;
pathology
;
Diagnosis, Differential
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Female
;
Humans
;
Neoplasms, Glandular and Epithelial
;
classification
;
metabolism
;
pathology
;
Ovarian Neoplasms
;
classification
;
metabolism
;
pathology
;
Tumor Suppressor Protein p53
;
metabolism
;
WT1 Proteins
;
metabolism
6.Studies on Establishment of Co-expression System and Function of Human Complement Regulatory Proteins MCP and CD59
Li XU ; Zhou-Zhou ZHAO ; Hui LIU ; Wen-Xin LI ;
China Biotechnology 2006;0(09):-
Recombinant expression vector pcDNA3-MCPCD59DP containing human membrane complement regulatory proteins(hCRPs) MCP and CD59 cDNA was constructed successfully by using two independent promoters.After transfected into NIH3T3 cells with calcium phosphate-DNA precipitate method,NIH3T3 pcDNA3-MCPCD59-DP transfectants were obtained by G418 selection.Extraneous genes integration was identified by PCR.The co-expression of human CD59 and MCP at both mRNA and protein levels was confirmed by using RT-PCR and Western blot analysis.Human MCP and CD59 cDNA were integrated in NIH3T3 pcDNA3-MCPCD59-DP genomic DNA after continuous 30 times passages,indicating that NIH3T3 pcDNA3-MCPCD59-DP were stable cell lines.Human complement-mediated cytolysis assays showed that NIH3T3 cells transfected stably with pcDNA3-CD59,pcDNA3-MCP,and pcDNA3-MCPCD59-DP were protected from C-mediated damage and co-expressed human MCP and CD59 provided more excellent protection against C-mediated attack as compared with either CD59 or MCP expressed alone.The dicistronic vector represents an effective and efficacy strategy to overcome C-mediated damage and has potential therapeutic value for effectively controlling complement activation and finally for preventing hyperacute rejection in clinical gene therapy.
7.Analysis of secondary high intraocular pressure after vitreoretinal surgery for proliferative diabetic retinopathy
hui, LI ; bei-wen, SONG ; xin-hua, DU ; qiang, WU
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(06):-
Objective To explore the correlative factors and management of secondary high intraocular pressure(IOP) after vitreoretinal surgery for proliferative diabetic retinopathy(PDR). Methods The data of 51 patients(54 eyes) with PDR after vitreoretinal surgery were collected.The incidence of secondary high IOP was obtained,and the correlative factors leading to high IOP were analysed.Besides,the therapeutic effects of management were observed. Results Twenty-six patients(26 eyes) experienced postoperative high IOP,with the incidence of 48.15%(26/54).It was revealed that the preoperative retinal detachment,the combined performance of crystal phacoemulsification,the practice of intraocular tamponade and the postoperative posterioruveitis were related to the occurrence of high IOP(P
8.Effectiveness and safety of acupuncture for supraventricular tachycardia: a systematic review and meta-analysis.
Wan-xin WEN ; Xian-sheng LI ; Xin-feng GUO ; Li ZHOU ; Wei-hui LV
Chinese Acupuncture & Moxibustion 2014;34(11):1146-1150
The effectiveness and safety of acupuncture for the treatment of supraventricular tachycardia were systematically reviewed. The randomized controlled trials (RCTs) regarding acupuncture for supraventricular tachycardia were searched in domestic and overseas databases, and the evaluation tool of bias risk in Cochrane Handbook 5.1.0 software was used to perform the evaluation of bias risk in literature, and RevMan 5.2 software was applied for statistics and Meta-analysis. Five RCTs involving 323 patients were included. The results showed that compared with the blank control group, the acupuncture reduced the heart rate by 18.8 times/min [95% CI (12.68, 24.92)]; the clinical effective rate in the acupuncture group was superior to that in the diltiazem group [OR= 3.11, 95% CI (1.50, 6.46)]; the difference of immediate effect between propafenone and acupuncture was not significant. No reports regarding adverse events was described in 5 RCTs. As was shown in the present evidence, acupuncture is safe and effective for the treatment of supraventricular tachycardia, but the level of evidence was low and the intensity of conclusion needed to be improved.
Acupuncture Points
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Acupuncture Therapy
;
adverse effects
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Humans
;
Randomized Controlled Trials as Topic
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Tachycardia, Supraventricular
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physiopathology
;
therapy
;
Treatment Outcome
9.Effect of Jinlida on changes in expression of skeletal muscle lipid transport enzymes in fat-induced insulin resistance ApoE -/- mice.
Xin JIN ; Hui-xin ZHANG ; Yan-fen ZHANG ; Wen-wen CUI ; Yao BI ; Qi-long HE ; Sheng-shan ZHOU
China Journal of Chinese Materia Medica 2015;40(6):1156-1160
OBJECTIVETo study the effect of Jinlida on changes in expression of skeletal muscle lipid transport enzymes in fat-induced insulin resistance ApoE -/- mice.
METHODEight male C57BL/6J mice were selected in the normal group (NF), 40 male ApoE -/- mice were fed for 16 weeks, divided into the model group (HF), the rosiglitazone group ( LGLT), the Jinlida low-dose group (JLDL), the Jinlida medium-dose group (JLDM), the Jinlida high-dose group (JLDH) and then orally given drugs for 8 weeks. The organization free fatty acids, BCA protein concentration determination methods were used to determine the skeletal muscle FFA content. The Real-time fluorescent quantitative reverse transcription PCR ( RT-PCR) and Western blot method were adopted to determine mRNA and protein expressions of mice fatty acids transposition enzyme (FAT/CD36), carnitine palm acyltransferase 1 (CPT1), peroxide proliferators-activated receptor α( PPAR α).
RESULTJinlida could decrease fasting blood glucose (FBG), cholesterol (TC), triglyceride (TG), free fatty acid (FFA) and fasting insulin (FIns) and raise insulin sensitive index (ISI) in mice to varying degrees. It could also up-regulate mRNA and protein expressions of CPT1 and PPARα, and down-regulate mRNA and protein levels of FAT/CD36.
CONCLUSIONJinlida can improve fat-induced insulin resistance ApoE -/- in mice by adjusting the changes in expression of skeletal muscle lipid transport enzymes.
Animals ; Apolipoproteins E ; deficiency ; genetics ; Blood Glucose ; metabolism ; CD36 Antigens ; genetics ; metabolism ; Carnitine O-Palmitoyltransferase ; genetics ; metabolism ; Dietary Fats ; adverse effects ; metabolism ; Drugs, Chinese Herbal ; administration & dosage ; Humans ; Hypoglycemic Agents ; administration & dosage ; Insulin ; metabolism ; Insulin Resistance ; Lipid Metabolism ; drug effects ; Male ; Metabolic Diseases ; drug therapy ; enzymology ; genetics ; metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Skeletal ; drug effects ; metabolism
10.Observation on efficacy of CT positioning scalp circum-needling combined with Chinese herbal medicine in treating poly-infarctional vascular dementia.
Xin LUN ; Li RONG ; Wen-hui YANG
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(6):423-425
OBJECTIVETo observe the short-term effect of patients with poly-infarctional vascular dementia (PIVD) treated by CT positioning scalp circum-needling (SCN) combined with Chinese herbal medicine.
METHODSEighty-nine patients of PIVD were enrolled and divided into the treated group (n = 57) and the control group (n = 32). They were all treated with oral taking of Fuyuan mixture (FYM, consisted of ginseng, medlar, salvia, bitter cardamon, etc). To the treated group, SCN was applied additionally with the unilateral area around the reflecting region (localized by CT) in scalp as main needling points and Ganshu, Shenshu, Zusanli, Hegu as supplementary points. Two courses of SCN were performed. The changes of clinical symptoms, intelligence and hemorrheological characteristics in patients were analysed.
RESULTSAfter two courses of treatment, the total effective rate in the treated group was 96.5%, which was better than that in the control group (75.0%), with significant difference (u = 2.423, P < 0.01); HDS scores increased in both groups after treatment, showing significant difference as compared with that before treatment (P < 0.01), hemorrheologic parameters were also apparently improved.
CONCLUSIONCT positioning SCN combined Chinese herbal medicine treatment has definite therapeutic effect in treating PIVD.
Acupuncture Therapy ; methods ; Aged ; Dementia, Multi-Infarct ; diagnostic imaging ; therapy ; Drugs, Chinese Herbal ; therapeutic use ; Electroacupuncture ; methods ; Female ; Humans ; Male ; Middle Aged ; Phytotherapy ; Scalp ; Tomography, X-Ray Computed