1.Thinking of Standardized Construction in Educational Administration Department under the Educational Management System of University and College
Chinese Journal of Medical Education Research 2006;0(07):-
The effectiveness and efficiency of university educational management would have a direct impact on universities' teaching performance.Moreover,it is important to undertake a further reformation for the educational management system of university and college and establish such a standardized,high efficient educational management system.Since they would be the milestones that improve universities'teaching performance constantly and ensure there is a persistent evolution in universities as well.
2.Ubiquitin and its role in the tumor
Xiaojia GAO ; Hui YANG ; Lin WU ; Fuxiang ZHOU ; Yunfeng ZHOU
Journal of International Oncology 2015;(3):188-191
Ubiquitin-proteasome pathway is one of the primary pathway in intracellular protein degrada-tion,therefore the ubiquitin conjugating enzyme D3(UbE2D3)which involved in the ubiquitin mineralization process can affect the biological effects accordingly to affect some protein and nucleic acid content and activity. The function that participate in modification and degradation of some cancer factors is vital in tumor cells,and followed by tumor biological behavior changing. Researches show that UbE2D3 correlates with human telomer-ase reverse transcriptase( hTERT),radiation sensitivity,aggressive,etc in breast cancer.
3.THE EXPRESSION OF 17? HSD TYPE Ⅰ AND Ⅲ IN IMMATURE MOUSE ADRENAL GLAND
Hui ZHU ; Min LIN ; Zuomin ZHOU ; Jiahao SHA
Acta Anatomica Sinica 1953;0(01):-
Objective To study the function of the X\|zone cells in the 5 days old male mouse adrenal gland and the relationship between the function and the sexual differentiation. Methods The technique of in situ RP\|PCR was used to detect the expression of type Ⅰ and Ⅲ 17? HSD mRNA. Results In the cells of X\|zone which located in the interface between adrenal crotex and medulla, there were expressions of type Ⅰ and Ⅲ 17? HSD.Conclusion\ The X\|zone cells of adrenal gland in immature mouse could synthesize androgen, enhanced the male sexual differentiation together with the androgen synthesized from the testis.\;[
4.DETERMINING THE CONTENT OF JASMINODIN IN MEI RONGCAPSULE WITH THIN LAYER CHROMATOGRAPHY
Hui MU ; Lin LI ; Ling ZHOU ; Xiaoli WAN ; Senke HU
Journal of Pharmaceutical Analysis 2001;13(1):81-82
Objective Jasminodin in Mei Rong capsule was determined by the method of thin layer chromatography. Methods The sample jasminodin was extracted with methanol and then the extract was chromatographed on silica gel GF254 plate with chloroform-methanol-water (10:3:1) as mobile phase and the chromatograms were scanned by using Shimadzu CS-930 dual wavelength TLCS in zegzag scanning mode at λs 370nm and λR 250nm.Results Calibration graph was rectilinear between 2.7μg~16.2μg per spot for the jasminodin. Conclusion Satisfatory results were obtained with the average recovery ratio of 99.76% ,RSD 2.27%.
5.Observation on effect of qi-supplementing blood-activating and stasis-removing principle in treating patients with systemic lupus erythematosus of blood-stasis type.
Jia-li WU ; Xio-hui BAO ; Zhi-lin ZHOU
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(11):860-861
Adolescent
;
Adult
;
Anti-Inflammatory Agents
;
therapeutic use
;
Diagnosis, Differential
;
Dipyridamole
;
therapeutic use
;
Drug Therapy, Combination
;
Drugs, Chinese Herbal
;
therapeutic use
;
Female
;
Humans
;
Lupus Erythematosus, Systemic
;
drug therapy
;
Male
;
Medicine, Chinese Traditional
;
Middle Aged
;
Phytotherapy
;
Prednisone
;
therapeutic use
;
Tripterygium
;
chemistry
7.Prevent effects of ex vivo oxygenated blood continuous perfusion on donor-lung injury
Xiaomao LONG ; Xiangwei LI ; Hui LIN ; Yifan ZHOU
Chinese Journal of Organ Transplantation 2013;(5):294-298
Objective To study the protective effect of normothermic ex vivo perfusion to prevent donor-lung injury.Method After being flushed with perfadex solution through the pulmonary artery and vein,the donor lungs were divided to control group (preserved with 4℃ cold static preservation,n =8) and experimental group (preserved with ex vivo oxygenated blood continuous perfusion,n =8).Pulmonary function indexes,including pulmonary vascular resistance (PVR),lung ventilation resistance(LVR),the left inferior pulmonary vein(LIPV) blood PO2,and lung water content,were evaluated.Lung injury were studied by light microscopic observation and detecting the expression of proimflammatory factor IL-1β was detected.Result (1) Lung function evaluation:in both group,PVR,LVR and lung water content gradually increased,LIPV PO2 gradually declined;But in the same time point PVR and LVR in group were were significantly less than in control group (P<0.05),LIPV PO2 in experimental group were were significantly more than in control group(P<0.05).(2)Lung injury evaluation:Lung tissue edema classification in both group were significantly higher than in normal lung(P<0.05),but classification in experimental group were significantly lower than in control group(P<0.05).The expression of IL-1β in experimental group (0.422 ± 0.132) were significantly lower than in control group(0.578 ± 0.163,P<0.05).Conclusion Ex vivo oxygenated blood continuous perfusion without ventilator is a feasible technique for lung preservation.It ameliorates hypothermic time-dependent ischemic injury.But further systems evaluation in complete physiologic condition is necessary.
8.Processing Technology Optimization of Prepared Morinda Officinalis Based on Nystose Content
Zhou CAN ; Xiong HUI ; Liao SHA ; Fan LIN
China Pharmacist 2015;(3):371-372,373
Objective:To optimize the processing technology of prepared Morinda officinalis based on nystose content. Methods:Orthogonal experiments and the nystose determination method in Chinese Pharmacopoeia (2010 edition) were used to optimize the pro-cessing technology. A Welch AQ-C18(250 mm ×4.6 mm,5 μm)chromatographic column was applied with methanol-water(3∶97)as the mobile phase, the column temperature was at 25℃, the flow rate was 0. 8 ml·min-1 , the injection volume was 10μl, and the drift tube temperature was at 40℃ with low temperature atomization. Results:The linearity of nystose was good within the range of 0. 214 8-0. 644 4 mg·ml-1 and the recovery was 99. 5%(RSD=3. 5%,n=6). Conclusion: On the basis of nystose content determination, the optimal processing technology of prepared Morinda officinalis is as follows:liquorice of 4%, stir fry time of 15min and the boiling pot temperature of 200℃.
9.Effect of Baoxin capsule on hemodynamics of myocardial ischemia in dogs
Hui YANG ; Weikang WU ; Jianping CHEN ; Lin ZHOU ; Chao CHENG
Chinese Journal of Pathophysiology 1986;0(03):-
AIM: To observe the effect of Baoxin capsules on hemodynamics of ischemic myocardium of dogs. METHODS: Fed Baoxin capsule for continuous three days, left anterior descending branch of the coronary artery of the dogs were ligated to observe the change of cardiac output, blood pressure and ?dp/dt max in different time of myocardial ischemia. RESULTS: Baoxin capsules increased the blood flow obviously, and increased left ventricular function simultaneously, the difference with ischemic group is significant (P
10.Distribution and drug resistance analysis of CR-AB and MRSA from 2011 to 2014
Guangzhou WANG ; Dongsheng HAN ; Hui TANG ; Lin ZHOU
International Journal of Laboratory Medicine 2015;(11):1525-1527
Objective To provide a scientific reference for the choice of antimicrobial drugs by analyzing the distributions and the antimicrobial resistances of Carbapenem‐resistant Acinetobacter baumannii (CR‐AB) and methicillin‐resistant Staphylococcus au‐reus (MRSA) in the Northern Jiangsu People′s Hospital .Methods All the CR‐AB and the MRSA isolated from hospitalized pa‐tients from January 2011 to March 2014 were collected and analyzed .Use the disk diffusion method for antimicrobial resistance tes‐ting .Results A total of 170 CR‐AB strains and 168 MRSA strains were isolated .CR‐AB mainly distributed in the ICU ,which ac‐counting for 61 .17% (104/170) .MRSA mainly isolated in neurosurgery ,about 27 .98% (47/168) .67 .06% of CR‐AB strains and 54 .17% of MRSA strains were from Sputum specimens .The antimicrobial resistance rate of CR‐AB to most antimicrobial drugs were reached 50 .00% ,the resistance rates to cefoperazone/sulbactam (27 .65% ) ,minocycline (21 .18% ) ,amikacin (19 .41% ) and tobramycin (12 .35% ) were all less than 30 .00% ,the strain that resistant to polymyxin was not found .The sensitivity rates of MR‐SA to linezolid ,vancomycin ,and tigecycline were 100 .00% ,and the resistance rates to nitrofurantoin and kuinuputing/ dalfopristin were low (less than 2 .00% ) .Conclusion The antimicrobial resistances of CR‐AB and MRSA are serious .In order to control effec‐tively the spreading of CR‐AB ,MRSA and other multi‐drug resistant bacteria ,it′s necessary for us to strengthen the management of key departments ,and select antimicrobial drugs based on the results of drug susceptibility testing .