Metabolic surgery have the ideal weight loss effect,can maintain the long-term ideal weight,and its effects on blood glucose control is better than the simple medical treatment.Therefore,metabolic surgery received widespread attention in China.More and more patients undergo metabolic surgery,but the surgeons often pay attention to the operation,neglecting the use of drugs after surgery.The patients are always complicated with a lack of vitamin and metabolic syndrome,such as type 2 diabetes mellitus,hypertension,polycystic ovary,sleep apnea,cardiovascular disease.Patients have taken drugs before surgery can cause esophageal reflux,ulcer,anemia,loss of calcium and other complications,patients need to be supplied with vitamins and minerals after surgery.So more attention should be paid to the rational application of drugs after surgery,to prevent adverse reactions from improper use of drugs,and reduce the incidence of postoperative complications.

Case based learning(CBL)is one of the teaching modes in clinic education and it is important to explore its teaching methods and qualities.This article discussed on how to use debate in CBL in neurology teaching for seven-year-program students including its organization,topic choosing,rules and specific process in order to provide references for teaching reform.

Background and purpose:Glut functioning as a vehicle for transferring glycose into cell,plays an important role in strengthening the glycometabolism process of malignant tumor.HIF-1?,a crucial transcriptional control gene in signaling cell to adapt to anaerobic microenvironment,can activate the expression of many anaerobic-responding genes which includes the expression of Glut1 gene,in order to supply energy for tumor under hypoxia.Our aim was to investigate the expression and clinical significance of Glut1 protein and HIF-1? protein as well as the correlation between them in human hepatocellular carcinoma(HCC). Methods :Immunohistochemical staining: EnVision method was used to detect the expression of Glut1 and HIF-1? in 45 cases with human hepatocellular carcinoma,and in 11 cases with normal hepatic tissue. Results :The positive expression rate of Glut1(66.7%) and HIF-1?(73.3%) in human hepatocellular carcinoma was higher than that in normal hepatic tissue(P

Leptin,a peptide hormone synthesized and secreted primarily by adipose tissue,plays an important role in the regulation of body weight,metabolic and endocrine responses.It has emerged recently as a protective factor in multiple organ resistance to injury.We reviewed the protective effect of leptin and its possible mechanism.

Carcinoma, Squamous Cell ; therapy ; Humans ; Laryngeal Neoplasms ; therapy ; Neoplastic Stem Cells

Coronary heart disease (CHD) is a major disease greatly harmful to the health of human beings. The incidence and case fatality rate of female CHD show an increasing tendency due to lack of enough attention. Through analyzing the epidemiology, risk factors, and clinical characteristics of female CHD, we emphasized that it is necessary to pay enough attention to the particularity of female CHD, and put forward the thinking way of diagnosis and treatment of integrative medicine as "integrating Chinese medicine and Western medicine by mutual complement of advantages; combining syndrome typing and disease identification by grasping laws; treating physically and mentally by a wholism concept; spreading health education, preventing and treating comprehensively".
Coronary Disease ; diagnosis ; therapy ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional ; methods ; Phytotherapy

The indices of the average level of major development and research capacity of the municipal Maternal and Child Health Institutions (MCH)in Sichuan Province were compared with the same indices of the national municipal MCH. we have noticed that the gap relating to the research capacity is significantly greater than the gap relating to the major development indices between Sichuan municipal MCH and the national municipal MCH. The result demonstrates the importance and necessity of strengthening the core subject construction in municipal MCH in Sichuan Province . Furthermore, it provides the ideas and methods of carrying out the core subject as references.

When petiole segment,blade and cotyledon slice of Trichosanihes kililhai were cultured on MS medium with different growth regulators,callus and adventitious root were induced easily but with difficulty for adventitious bud. Yet adventitious bud can be induced when whole small blade,large blade segment and adventitious root tip were cultivated on MS medium with 0. 5mg/L of 6~13 A and propagated extensively whentransplanted on new media for successive transfer culture. When adventitious root bud was cultivated on MS medium wth 0. 5mg/L of NAA and 0. 5mg/L of 6~ 13A,shoot appeared,which can be grown into plantlet though the survival rate was not very satisfactory when further transplanted. Effect of blade segment size and its slicing technique,on the differentiation of adventitious bud was discussed.

Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.