China Journal Full-text Database (CJFD) was undertaken to identify relevant articles. This article aims to classify data on ossicular replacement prosthesis (ORP) and to analyze the application of different kinds of ORP to auditory rehabilitation. Studies demonstrated that different ORP had different advantage or disadvantage. Autologous cartilage is convenient to obtain and difficult to absorb such as antilobium cartilage, nasal septum cartilage and so on. But degeneration and absorption are detected in a long-term. Homograft tooth with good histocompatibility, tooth sound conduction, weak rejection and high stability is easy to collect, to store for a long time, and to apply in clinic, as well as without organic matter after disposing. However, this kind of tooth is easy to move and cannot be used by most physicians. Titanium ORP possesses good biocompatibility and histocompatibility, avirulence, corrosion resistant properties, light mass, and is hard to dislocate, can firmly connect to the stirrup bone, resulting in a postoperative significant outcome. Bioceramic ORP is widely used in ear surgery, because it has inorganic salt component, good biocompatibility, and low dislocation rate. With deep studies on biomaterials and discovery of new materials, many scholars have designed a compound auditory ossicle to combine the predominance of various materials and to avoid their shortcomings.

This article analyzed both the etiopathogenisis and high risk factors of DVT in patients of orthopaedics diseases. Furthermore, it explained both the prophylaxis and therapies of DVT from traditional Chinese medicine (TCM),western medicine, and combined traditional Chinese and western medicine point of view.

Objective To develop a new intelligent medicine chest to update medical prescription and select medicine automatically based on the patient's requirements.Methods Information interaction was realized with Bluetooth and the connection between Java-based Yiyi health management app and a PLC module of the chest,so that auto dressing,medicine sorting and distribution could be executed according to medical prescription.The medicine chest was composed of PLC,constant-speed motor,sheave,lead rail mechanism,guide slot for medicine distribution,base,stricking mechanism and pushpull electromagnet.Results The chest eliminated medicine abuse,missed use or excessire use of the elderly.Conclusion The chest gains advantages in structure and function,and thus is worthy promoting practically.

Objective:To evaluate the application status and change trends of insulin and its analogs in Nanjing area during 2011 to 2013. Methods:The varieties, sales amount and DDDs of insulin and its analogs in 43 hospitals of Nanjing during 2011 to 2013 were analyzed. Results:The use of insulin and its analogs was increased year by year from 2011 to 2013 with the average annual growth rate of 16%. Glargine, pre-mixed insulin 30R, aspart 30, human insulin and aspart ranked the top five in the sum of money with the proportion above 80%. Pre-mixed insulin 30R, aspart 30, glargine, human insulin and common insulin ranked the top 5 in DDDs. Conclusion:The application of insulin and its analogs is wide in clinics, and the usage and sum of money both show rapid growth trend.

Objective To make the clinical evaluation of Targis/Vectris restorations. Methods 337 cases with Targis/Vectris restorations were rechecked 12～50 months after cementation respectively. The restorations were evaluated clinically according to the USPHS standard. Results The changes of Targis/Vectris restorations in colour match, boundary line, wear and tear, marginal adaptation and surface grain were not obvious within 12～50 months. The secondary caries were not found. The successful rate of the restorations was 95.4 %.Conclusion The clinical prosthetic results of Targis/Vectris restorations are reliable.

Acute Kidney Injury ; etiology ; Child ; Exercise ; Humans ; Male

Objective To develop a novel approach of transfecting the exogenous gene safely and effectively mediated by receptor according to the cavitation effect of ultrasound-mediated microbubble destruction. Methods C-myc antisense oligonucleotide(ASODN) and galactosylation polylysine(G-PLL) which was fluoresce in-labeled specificity ligand and SonoVue microbbule were coupled by electrostatic interaction. SMMC-7721 cell with c-myc ASODN were transfected in vitro by ultrasound-mediated microbubble destruction to investigate the effect of c-myc ASODN on it. The c-myc mRNA gene expression of liver cancer SMMC-7721 cells was detected. Results Cultured with 10% SonoVue microbubble and under ultrasound at 1.5 MHz,1.0 W/cm2, 10% duty cycle,60 s respectively,the SMMC-7721 cells had not been changed significantly. Reverse transcription polymerase chain reaction(RT-PCR) assay showed that c-myc expression was decreased in transfected cells(P<0.01). Conclusions Receptor-mediated targeted microbubble destruction by ultrasound can enhance the exogenous gene transfection and expression. It is a promising method in gene therapy of liver cancer.

Objective To investigate the current situation of occupational burnout of doctors in west China and to explore the relationships among burnout,social support and work-family conflicts.Methods 611 doctors in west China were assessed by Chinese Maslach burnout inventory( CMBI),social support rating scale(SSRS) and work-interference-with-family and family-interference-with-work questionnaire.Results 14.1％ of the doctors in west China got high scores on emotional exhaustion(EE),49.4％ of them high scores on depersonalization(DP) and 33.1％ high scores on reduced personal accomplishment (RPA) ; 27.3％ experienced mild burnout,43.7％ moderate burnout and 3.3％ severe burnout.Doctors who had worked for 5 ～ 10 years and those for 11 ～ 20 years experienced greater EE.Those doctors with bachelor or master degree and intermediate or senior titles got highest level of depersonalization.Doctors in second-class hospitals got highest scores of depersonalization,and those who worked in first-class hospital experienced the highest sense of achievement.Logistic regression analysis showed that social support was a protective factor for burnout,but the conflict between work and family was a risk factor.Conclusion The status of occupational burnout among the doctors in west China is in a grave condition,the balance between family and work,and social supporting is crucial for doctors to resist the occupational burnout.

Objective To detect P0.1 and respiratory function of patients with cerebral infarction(CI)and analyze the effect of cerebral infarction on respiratory function. Methods Arterial blood gases, respiratory drive and lung function were measured in 35 cases with CI and 15 healthy controls. The figures were analyzed by SPSS 10.0. Results The PaO0.2 (mm Hg, 75.80±4.12, 1 mm Hg=0.133 kPa), SaO2(%,94.97±0.78) and Plmax(kPa,4.076±2.443) were lower than those in the healthy control group (88.68±3.77, 96.40±0.48 and 7.747±0.599,t=-8.310,-5.731,-5.439,all P=0.000). P0.1 max and P0.1/MV in the CI group were lower than those in the healthy control group;the P0.1 did not have significant difference in these two group; the P0.1/P0.1max and P0.1/Plmax in the CI group were significantly higher than those in the healthy control group; the PImax was correlated with PO2, O2sat, P(A-a) O2, P0.1max, P0.1, P0.1,/PImax, P0.1/P0.1max, FVC, FEV1.0 and PEF; the PEmax was correlated with P0.1/ PImax, FVC, FEV1.0 and PEF. Conclusion The respiratory function of patients with CI has been impaired, the oxygenated index is cut down and the respiratory drive and respiratory drive store are decreased.

Objective To investigate the subthreshold depression for long-term survivors after breast cancer surgery and its effect on their quality of life (QOL). Methods The self-made general questionnaire, Centre for Epidemiological Studies Depression Scale (CES- D), Hamihon Rating Scale for Depression and Functional Assessment of Cancer Therapy- Breast were used to investigate the subthreshold depression and its effect on their QOL for 210 long-term survivors after breast cancer surgery. The difference in general conditions and score of QOL between the subthreshold depression and non-subthreshold depression groups was also compared. Results The subthreshold depression with incidence rate of 46.67%(98/210) was observed for the log-term survivors after breast cancer surgery in this study. The results indicated that the age (≤50) (OR=5.627, 2.662,P<0.01), marriage (unmarried, divorced or widowed) (OR=5.087, P<0.01), employment (unemployed, sick leave or retired) (OR=2.077,P<0.05) and low income (<3000 RMB/month) (OR=3.375,P<0.01) were the key factors that led to the occurrence of subthreshold depression. The score of QOL for the subthreshold depression group were lower than those of the non-subthreshold depression group (t=-6.653--2.926,P<0.01), and had a significantly negative correlation with score of depression and QOL (β=-0.362--0.132). Conclusions A high incidence rate of subthreshold depression for long-term survivors after breast cancer surgery was observed. The incidence rate of subthreshold depression increased for the patients with younger age, low income,unmarried or unemployment. Due to their low QOL, attentions should be paid to the early detection and early prevention for the long-term survivors with subthreshold depression after breast cancer surgery.