OBJECTIVE: To establish the quality standard of Guanxinjing capsule. METHODS:Ligusticum chuanxiong, Borneolum Syntheticum, Radix Paeoniae Rubra, Panax ginseng and Panax notogiseng were identified qualititively by TLC. The content of Protocatechuic aldehyde in salvia miltiorrhiza was determined by HPLC. RESULTS: The TLC spots were distinct and well-separated. The average recovery of the added sample was 99.91% and RSD was 1.56%. CONCLUSION: The established standard is suitable for the quality control of Guanxinjing capsule.

OBJECTIVE:To optimize the coating technology of modified release film of budesonide colonic localization tablet. METHODS: The effect of the coating parameters such as spray gun position, spraying rate, spraying atomization pressure, intake air temperature and flow, temperature of tablet bed on the microporous semipermeable film and the enteric film of localization tablet were investigated, respectively. RESULTS: The distance between spray gun muzzle and tablet bed was established as 10～20 cm; the spraying rates of the microporous semipermeable film and the enteric film of localization tablet were 3 and 1 mL?min-1, respectively, with their spraying atomization pressure at 2 and 1.5 bar(1 bar=105 Pa), intake air temperature at 50～55 ℃ and 40～45 ℃, temperature of tablet bed at (40?1) ℃ and (30?1) ℃, flow rate of intake air at 5 and 7 m3?min-1 respectively. The weight of the optimized localization tablet after being coated with semipermeable film and enteric film increased by 10% and 5%, respectively. The cumulative drug release within 24 h reached (77.5?8.6)% and the lag time was (6.0?0.5) h. CONCLUSIONS: The optimized coating technology is suitable for the preparation of modified film of budesonide colonic localization tablet.

PBL and CTM integration method is a kind of heuristic education mode of regarding student as the center of education.In order to explore the application result of this teaching method in the curriculum of nursing ethics laws and regulations,we put this mode into practice and regard nursing students as research objects.Questionnaire investigation and paper test are applied to evaluate the teaching effect.The study result shows that PBL and CTM integration method is certainly a well-established method to enhance teaching quality in the curriculum of nursing ethics laws and regulations.

Acute cerebral infarction needs a fast and effective imaging examination to help determine the diagnosis,analyze the causes,guide the treatment,and determine the prognosis.Multimodal CT examination obtains a wide range of reformation in a single scan,including anatomy,hemodynamics and etiology,and provides objective imaging evidence for comprehensive evaluation and appropriate treatment of cerebral infarction.This article reviews the application of this technology in acute cerebral infarction.

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Common Cold ; prevention & control ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged

Congenital heart disease and airway anomalies are correlated,and some special cardiovascular anomalies accompanying with airway anomalies like vascular tings,have a high morbidity.Congenital heart disease with airway anomalies is usually ignored in clinic.It should be considered that congenital heart disease with airway anomalies exists in children with the symptoms,such as repeated stridor,respiratory failure,difficult intubation or failure of postoperative ventilator weaning.Multidetector helical CT and bronchoscopy are important for making early diagnosis and guiding management for congenital heart disease with airway anomalies.The choice of therapeutic approaches depends on the type of airway anomalies,location and degree of the lesion.

Objective To analyze clinical features of papillary thyroid microcarcinoma(PTMC) and to evaluate the diagnosis and treatment for PTMC.Methods The clinical data of 447 cases of PTMC receiving surgical treatment and confirmed by pathology were reviewed.Color Doppler ultrasonography was used to identify thyroid nodules and cervical lymph nodes,and frozen section was used to confirm the pathological diagnosis during operation.104 cases received unilateral lobectomy,22 cases received unilateral lobectomy plus isthmectomy,321 cases received total thyroidectomy,257 cases underwent central neck dissection,and 54 cases underwent lateral neck dissection(level Ⅵ included).All cases took levothyroxine to maintain low TSH level after operation,and were followed up through telephone or in out-patient clinic.Results Central compartment node metastasis was found in 144 patients,and lateral neck metastasis was found in 41 cN1 cases.The age,extra-capsular invasion and multifocal carcinoma were independent risk factors of PTMC.The number of positive nodes in level Ⅵ was positively correlated with the risk of lateral node metastasis.395 cases were followed-up successfully for 20 to 42 months,with the media follow-up of 32 months.During the follow-up,recurrence or metastasis was found in 15 cases,and no death happened.Conclusions PTMC has no specific symptoms,and was difficult to be diagnosed before operation.Physical examination and color Doppler ultrasonography should be used as routine examination.Thyroid lobectomy and total thyroidectomy plus central node dissection should be major surgical treatment for PTMC patients.Lateral neck dissection should be considered in all cN1 patients.

Objective To investigate and analyze the residents′knowledge and satisfaction on basic public health services in five districts of Gansu ,to judge the implementation effect of the current policy ,in order to provide the suggestion to improve the effect of the implementation of the policy of basic public health services .Methods Based on typical sampling method ,1 688 rural and urban residents had been investigated coming from five counties in Gansu by using questionnaires to survey .Results The de‐gree of residents′knowledge about the policy was low (57 .23% );the residents could know about the policy through a variety of ways ,and mainly for medical staff to promote by approaching their homes ;91 .94% of surveyed residents thought that policy service was more convenient when they were accepting ;90 .99% of surveyed residents thought that they satisfied with the service attitude of staff ;82 .35% of surveyed residents believed that the policy service effects was obvious ;90 .11% of surveyed residents overall satisfied with the service of policy .The above results were different in proportion in various counties(P<0 .05) .Conclusion The degree of residents′knowledge and satisfaction on basic public health services in five districts of Gansu still needs to be improved .

Objective To compare the CT and magnetic resonance imaging (MRI) examination in the application value in the diagnosis and treatment of osteonecrosis of the femoral head.Methods 42 cases of early avascular necrosis of the femoral head were underwent CT and MRI examination,and two kinds of imaging methods were compared.Results MRI diagnosis of avascular necrosis of femoral head in 1 patient detection rate (87.50％) was significantly higher than that of CT (56.25％),and the difference was statistically significant (x2 =3.96,P ＜0.05).While the overall MRI coincidence rate (96.78％) and CT (88.71％) had no significant difference (x2 =3.00,P ＞0.05).The detection rate of MRI diagnosis for single cystic degeneration (93.75％) and CT (75.00％) had no significant difference (x2 =2.13,P ＞ 0.05).MRI in the diagnosis of bone trabecular structure fuzzy detection rate (75.00％) was significantly higher than that of CT (12.50％),and the difference was significant (x2 =12.70,P ＜ 0.05).Conclusion In the early diagnosis of osteonecrosis of the femoral head,MRI could detect changes of early avascular necrosis of the femoral head bone marrow edema and fat necrosis sensitively.MRI was superior to CT in accuracy,harmfulness and sensitivity.It could intuitively reflect the shape of lesions and pathological changes.So it could improve the overall level of diagnosis of osteonecrosis of the femoral head.

Objective:To evaluate the application status and change trends of insulin and its analogs in Nanjing area during 2011 to 2013. Methods:The varieties, sales amount and DDDs of insulin and its analogs in 43 hospitals of Nanjing during 2011 to 2013 were analyzed. Results:The use of insulin and its analogs was increased year by year from 2011 to 2013 with the average annual growth rate of 16%. Glargine, pre-mixed insulin 30R, aspart 30, human insulin and aspart ranked the top five in the sum of money with the proportion above 80%. Pre-mixed insulin 30R, aspart 30, glargine, human insulin and common insulin ranked the top 5 in DDDs. Conclusion:The application of insulin and its analogs is wide in clinics, and the usage and sum of money both show rapid growth trend.