Objective To investigate the effects of different tidal volume (V_T) on arterial oxygenation and intrapulmonary shunt(Q_S/Q_T) during one lung ventilation(OLV).Methods Sixty patients scheduled for selective lobectomy under left lateral decubitus position were randomly divided into groups of A,B and C with 20 cases each.After bronchial induction,two lung ventilation(TLV) was performed with V_T 10 ml/kg,frequency(f) 12 breaths per minute(BPM),ratio of inspiration to expiration(I: E) was 1:2 at first.During OLV,I: E was kept steady,V_T 6 ml/kg and f 20 BPM were chosed in group A,V_T8 ml/kg and f 15 BPM in group B,V_T 10ml/kg,f 12 BPM in group C.Blood gas analysis was determined before OLV (T_1) and at 10 min(T_2) ,20 min(T_3) ,and 30 min after OLV (T_4).Q_S/Q_T and lung complience(Cdyn) was calculated.Results OLV Compaired to T_1,PaO_2 and Cdyn were lower (P<0.05) and Q_S,Q_T and peak airway pression were increased (P<0.05).The decrease of PaO_2 was more in groups of A and C than that in group B(P<0.05).Conclusion During OLV,a better PaO_2.may be maintained with the ventilation parameters of V_T8 ml/kg and f 15 BPM with less increase in Q_S/Q_T and higher Cdyn.

Objective To observe the clinical curative effect and the serum CPR changes by the treatment principle of Yangyin-Huayu for the patients with recurrent hemoptysis of Bronchiectasis. Methods A total of 64 patients were enrolled and divided into 2 groups according to the random number table method, 32 patients in each group. The control group was treated with the injection of blood clotting enzyme, pituitrin, levofloxacin lactate. And the treatment group was treated with the Yangyin-Huayu on the basis of the control group. Two groups were treated for 10 days. The CPR was detected by the double optical path immune turbidity analyzer. And the clinical effects, symptoms and signs scores were compared between before and after treatment and between two groups. Results Compared with the total effective rate of control group 84.38%(27/32), the treatment group was 96.88% (31/32) and significantly high (χ2=6.372, P<0.01). After treatment, the levels of serum CPR (2.45 ± 1.42 mg/L vs. 6.19 ± 2.34 mg/L, t=4.671) in the treatment groupwas significantly lower than that in the control group (P<0.01). The scores of cough (0.62 ± 0.91 vs. 1.34 ± 0.58, t=5.364), sputum (0.14 ± 0.28 vs. 0.68 ± 0.72, t=4.035), haemoptysis (0.10 ± 0.65 vs. 0.62 ± 0.26, t=5.012), fever (0.04 ± 0.31 vs. 0.76 ± 0.07, t=3.026), breathing difficulties (0.12 ± 0.41 vs. 0.69 ± 0.05, t=4.010) in the treatment group were lower than those in the control group (P<0.01). Conclusions The treatment principle of Yangyin-Huayu combined with conventional western medicine therapy can improve the patients with recurrent hemoptysisin the fields of symptoms, signs, the serum level of CPR, and total effect rates.

Caveolin are a family that proteins are highly conserved and located at the mammalian plasma membrane.They include four isoforms:Cav-1,Cav-2,Cav-3 and Cav-4.Caveolin proteins are implicated in endocytosis,lipid metabolism and cellular signaling.There is recent evidence that Cav-1 expression levels in tumour have been associated with tumour growth and metastasis,stromal car-1 expression downregulated have been also associated with mutli-tumor metastasis.

Dysarthria ; etiology ; Encephalitis, Viral ; complications ; Facial Paralysis ; etiology ; Humans ; Syndrome

Objective To investigate the influencing factors on the nursing ability of caregivers who provide service for elderly Methods patients with cardiovascular disease in medical and nursing combination institutions. A total of 276 caregivers who provide service for elderly patients with cardiovascular disease in medical and nursing combination institutions in Beijing urban area were selected as research subjects using the judgment sampling method. The Chinese Caregiver Task Inventory, eHealth Results Literacy (eHL) Scale and Sense of Coherence (SOC) Scale were used to investigate the nursing ability, eHL and SOC. The scores of nursing ability, eHL and SOC of the caregivers were (28.3±6.1), (17.0±5.9) and (69.0±9.4), respectively. The results of multiple linear regression analysis showed that caregivers who regarded the occupation as a career, had general or good subjective income, cared for disabled subjects, had a good basic knowledge of cardiovascular disease and qualified eHL had P P Conclusion relatively high nursing ability (all <0.01). The higher the SOC score, the higher the nursing ability ( <0.01). Occupational recognition, subjective income, master the basic knowledge of cardiovascular diseases, disability of nursing patients, eHL and SOC were factors affecting the nursing ability of caregivers who provide service for elderly patients with cardiovascular diseases in urban medical and nursing combination institutions.

Objective Toevaluate the postgraduates'satisfaction toAlma Mater's education of Peking University Health Science Center from 1998 to 2008.Methods Twenty to thirty percent of postgraduates who graduated from PUHSC and obtained domestic employment were selected and a questionnaire survey was conducted.Correspondence analysis was applied to intuitively show the relation of some variables.Results Postgraduates were satisfied with the education of PUHSC.The moral education,vocational ethics and teaching management of PUHSC was excellent.The campus life,society practice activities,administrative management and logistics service of PUHSC need to be improved.Methodology courses,foreign language courses,professional courses and writing courses should be reinforced during the education.Conclusion The postgraduates were satisfied with Alma Mater's education.It was pointed that postgraduate education of PUHSC was adapted to social needs.

Two hundred and thirty two patients with essential hypertension were divided into intervention and control groups (116 in each) ,by the end of study period (from January 2005 to January 2006) 106 patients in intervention group (91.4%) and 102 in control group (87.9%) completed observation.The main findings were as follows: the blood pressure control rate in intervention group was higher than that in controls (X2=23.92,P <0.01) ;the family adaptability(X2 =31.12,P <0.01),family caring(X2=37.90 ,P<0.01),family communication (X2= 17.91,P<0.01) and family function(X2 = 8.26,P<0.01)in intervention group were better improved than those in control group.The results suggest that family can be effective resources for improvement of patients with essential hypertension.

Overgrowth in children and adolescents are not rare.The cause of overgrowth includes physiological and pathological growth accelerating.Physiological overgrowth contains familial tall stature and obesity.Pathological o-vergrowth includes endocrine metabolism diseases,chromosomal abnormalities,and a variety of genetic syndromes.Most patients were neglected.The standardized diagnosis and treatment for overgrowth is especially essential.In this review, the etiology and the progress of diagnosis and treatment for overgrowth were concluded in children and adolescents.

OBJECTIVE To discuss the constitution and drug sensitivity of pathogens that cause pulmonary infection in NICU. METHODS Sputa were collected from patients hospitalized in NICU from Mar 2006 to Mar 2007 and analyzed for distribution and drug sensitivity of pathogenic bacteria. RESULTS All 555 strains of pathogenic bacteria were isolated. The most common pathogens were Pseudomonas aeruginosa(183 strains,33.0%),Staphylococcus aureus(114 strains,20.5%) and Klebsiella pneumoniae(56 strains,10.1%). Nearly most pathogenic bacteria were multi-resistant to commonly used antibiotics. Meticillin resistant strains of S. aureus accounted for 97.4%. The percentange of fungi strains was increasing in NICU. The main isolated strains were Candida tropicalis(5.9%),C. albicans(3.8%)and C. glabrata(3.6%). And all of the fungi were sensitive to amphotericin B. fluconazole. and ketoconazole. CONCLUSIONS Pulmonary infections in NICU are mainly caused by Gram-negative bacteria with high rate of drug resistance. It can be of great importance to make drug sensitivity tests at regular intervals to guide the use of antibiotics.

Objective To investigate the complications of laparoscopic exploration of the common bile duct,and its prevention.Methods From June 2003 to June 2007,a total of 124 patients received laparoscopic exploration of the common bile duct in our department,13 of them developed complications.The data of these 13 patient were analyzed retrospectively.Results Among the 13 cases,3 had intraoperative perforation of the common bile duct(one of them was complicated with perforation of the duodenum),2 had intraoperative hemorrhage;1 had postoperative perforation of the duodenum,2 had biliary leakage(treated by primary suture),1 had postoperative intra-abdominal hemorrhage,and 4 had residual stones in the bile duct.All the complications were cured.Conclusions Strict indications and high-level techniques are important factors for laparoscopic exploration of the common bile duct.The prognosis of the patients can be good as long as open surgery is carried out at proper time and the complications are treated appropriately.