4.Visual cortex activation range of color vision with BOLD-fMRI in anisometropia amblyopia children
Hui-Fang, ZHANG ; Zhen-Guo, YAN
International Eye Science 2014;(8):1484-1487
AIM:To analyze the recovery of visual cortex activation range of color vision in anisometropia amblyopia children after treatment by using blood oxygen level dependence-functional magnetic resonance imaging ( BOLD- fMRI ) and SPM8 software.
METHODS:Self-control study. This fMRI study directly compared activity in visual cortex produced by color monocular stimulation in 13 monocular anisometropia amblyopia children. The project of study was blocked design. The data of functions and anatomical MRI was stimulated by three-primary colors and was preprocessed and analyzed by SPM8 that based on MATLAB software. According to the data, we compared the change of the central area of color vision when first visit and 1, 2 ,4wk after treatment.
RESULTS: The BA17, BA18, BA19 and BA37 of amblyopia children were different activated after they accepted the three-primary colors stimulation (P<0. 01). After 4wk treatment, amblyopia children accepted red stimulation, the visual cortex activation range without expanding; after accepting green stimulus, on the left side of the visual cortex BA37, BA19, BA20, the average t value were 3. 5210, 3. 2716, 3. 1534 ( P< 0. 01 ); after accepting blue stimulation, the scope of the right side of visual cortex at BA19, BA18 were expanded to different extent, the average t value were 3. 7345, 3. 2701 (P<0. 01).
CONCLUSION: After 4wk treatment, visual cortex activation of color vision of anisometropia amblyopic children is expanded, but with low extent, after the short-term treatment of amblyopia, visual cortex activation of color vision has a certain degree of recovery but not obvious.
6.Experimental study on expression of osteopontin in viral myocarditis.
Fang-ying YIN ; Jing-hui SUN ; Yan-yan HAN
Chinese Journal of Pediatrics 2008;46(9):710-711
Animals
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Male
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Mice
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Mice, Inbred BALB C
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Myocarditis
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metabolism
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virology
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Myocardium
;
metabolism
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Osteopontin
;
metabolism
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Virus Diseases
;
metabolism
7.Analytical method for benzene, toluene, xylene, hexane, trichloroethylene in gooey agent by gas chromatography.
Hui-Fang YAN ; Xiao-Shuang XIE ; Hui-Fang DU ; Jing ZHANG ; Chun-Ling LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(4):303-305
Benzene
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analysis
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Chemical Industry
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Chromatography, Gas
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methods
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Humans
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Occupational Exposure
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analysis
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Toluene
;
analysis
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Trichloroethylene
;
analysis
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Xylenes
;
analysis
8.Function and mechanism of tumor suppressor gene FBW7 in tumorigenesis.
Hui-jie HUANG ; Fang ZHENG ; Fang-ping XU ; Yan-hui LIU ; Heng-guo ZHUANG
Chinese Journal of Pathology 2013;42(3):214-216
Animals
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Carcinogenesis
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Cell Cycle Proteins
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genetics
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metabolism
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Cyclin E
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metabolism
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F-Box Proteins
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genetics
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metabolism
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F-Box-WD Repeat-Containing Protein 7
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Gene Silencing
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Genes, Tumor Suppressor
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Humans
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Mutation
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Myeloid Cell Leukemia Sequence 1 Protein
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metabolism
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Neoplasms
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genetics
;
metabolism
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pathology
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Proto-Oncogene Proteins c-myc
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metabolism
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Receptors, Notch
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metabolism
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Signal Transduction
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TOR Serine-Threonine Kinases
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metabolism
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Ubiquitin-Protein Ligases
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genetics
;
metabolism
9.One case report of sudden death due to ruptured aortic sinus aneurysm into right ventricle.
Hui-fang MA ; Guo-hua XUE ; Shou-yan ZHANG
Chinese Journal of Cardiology 2011;39(11):1048-1049
Adult
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Aortic Rupture
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pathology
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Death, Sudden, Cardiac
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etiology
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Heart Ventricles
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pathology
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Humans
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Male
10.Effects of topiramate on hydrous capacity in brain tissue and neurons apoptosis in rats with perinatal ischemic brain damage
Hui WU ; Yanqiu FANG ; Dongxuan WANG ; Yan TAN
Journal of Jilin University(Medicine Edition) 2006;0(06):-
Objective To investigate the effects of topiramate on neurons apoptosis and the hydrous capacity in brain tissue in rats with perinatal acute ischemic brain damage.Methods The perinatal acute ischemic brain damage model was established by ligation of both uterine arteries of full-term pregnant Wistar rats(n=315).They were divided randomly into topiramate one and five times groups and hypoxic-ischemia(HI) group(n=105),and normal collate group consisted of 105 normal Wistar rats.The effects of topiramate were observed by the changes of hippocampal apoptosis cells labeled in situ end TUNEL methods at different time spots(postnatal 3 h,6 h,24 h,(3 d,7 d),14 d,21 d,28 d) and the hydrous capacity in brain tissue within 7 d after birth.Results The hydrous capacity in brain tissue in administering drug one time group was remarkably less than that in HI group at 12 and(72 h after) birth,and it in administering drug five time group was remarkably less than those in HI group and administering drug one time group at 48 and 72 h after birth(P