1."The Window Effect "of 1800MHz Electromagnetic Radiation on Oxidative Stress in Skin of SD Rats
Yun-zhen MU ; Xi-nan WU ; Yuan ZHANG ; Hua LIN ; Hue-xing WU ; Qing XING
Journal of Kunming Medical University 2018;39(6):22-25
Objective To investigate the effect of 1 800 MHz electromagnetic radiation on activity of SOD and GSH-Px in the skin tissues of SD rats.Methods A total of 98 healthy SD rats with SPF level,aged 4 weeks, were randomly divided into radiation group and control group.The radiation group was totally exposed under 1 800 MHz electromagnetic wave with seven different power density of radiation of 0.1 mW/cm2,0.3 mW/cm2,0.5 mW/cm2 , 0.7 mW/cm2, 0.9 mW/cm2, 1.0 mW/cm2and 1.2 mW/cm2respectively.It lasted 21 days and for a period of 12 hours a day. After radiation,the activity of SOD and GSH-Px in the skin tissues were detected by enzyme marker. Results In radiation group,the activity of SOD and GSH-Px in the skin tissues of SD rats were decreased under 0.3 mW/cm2and 0.5 mW/cm21 800 MHz electromagnetic wave. Compared with the control group, there was a significantly difference in radiation group (P<0.05) .While under other four 1 800 MHz electromagnetic waves, the activity of GSH-Px and SOD in the skin tissues showed no statistical difference between the two groups (P>0.05) . Under 1 mW/cm21 800 MHz electromagnetic wave, the activity of GSH-Px showed no statistical difference between two groups (P>0.05) . Conclusion The power density of 0.3 mW/cm2and 0.5 mW/cm21 800 MHz electromagnetic wave can reduce the activity of GSH-Px and SOD in the skin tissues of rats.