Objective To establish the HPLC fingerprints of petroleum ether parts from five traditional medicine (Alpinia officinarum Hance, Alpinia galangal ( L.) Wild, Alpinia galanga Will., Alpinia katsumadai Hayata, and Alpinia oxyphylla Miq), and to explore the similarities and differences of chemical composition,as well as the correlation between the genetic relationship and the chemical composition. Methods HPLC method was used to analysis the five traditional medicines. The data were evaluated by using the"similarity evaluation system for chromatographic fingerprint of TCM" software. Results The similarity chemical composition from Alpinia officinarum Hance,Alpinia galangal(L.) Wild,Alpinia galanga Will.,Alpinia katsumadai Hayata,and Alpinia oxyphylla Miq in ethyl acetate were 0.741,0.855,0.610,0.510, 0.680,respectively. Conclusion Though there were differences of fingerprint peak of petroleum ether parts between five the traditional Chinese medicines, similarities were also observed among them.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

Objective To analyze the effect of ICD coding defects on disease grouping of Diagnosis-Intervention Packet(DIP)high-cost biased cases.Methods Data from the home page of medical record and the cost settlement of 342 DIP high-cost biased cases in a tertiary grade A general hospital from 2019 to 2021 were collected.The quali-ty control of ICD codes of DIP high-cost biased cases was performed.After the incorrect ICD codes were cor-rected,the cases were grouped again by DIP.The changes of disease grouping and score before and after the coding correction were analyzed by paired Wilcoxon signed-rank test.Results The defect rate of ICD coding with DIP high-cost biased cases was 19.30％,the defect rate of ICD coding for main diagnosis was 9.36％.The ratio of coding defects of tumor,respiratory system and cardiovascular disease accumulates to 57.53％.The defect rate of coding for operation was 7.93％.Among the 66 cases with ICD coding defects,35 cases with revised codes were regrouped,and the classification and score of DIP disease were changed.The DIP median score increased from 1 022 to 1 089,which was statistically significant(Z=-2.71,P=0.03).Conclusion The DIP high-cost biased cases had a high rate of ICD coding defects.The defect rate of ICD coding in the diagnosis of tumor,respiratory system and circulatory system was prominent.The hospital should make specific measures to improve the quality of ICD coding,provide the key support for the DIP disease grouping,and promote the hospital fine management and high-quality development.

OBJECTIVETo conduct a systematic review of the safety and efficacy of enhanced recovery after surgery(ERAS) program in perioperative management of pancreaticoduodenectomy.

METHODSA computerized search was performed in databases including PubMed, Embase, Medline, Web of Science, Cochrane Library, CNKI, Wanfang and VIP for randomized controlled trials (RCTs) or clinical controlled trials (CCTs) describing an ERAS program in patients undergoing pancreaticoduodenectomy published between January 1966 and May 2014. After assessment of methodological quality and data extraction, meta-analysis was performed using RevMan 5.2.0 software.

RESULTSSix RCTs and 8 CCTs including 2565 patients were selected for this study, including the study group(n=1366) and the control group (n=1199). Compared with the control group, the study group had a shorter length of hospital stay(WMD=-3.67, 95% CI:-5.66--1.68, P<0.05), lower postoperative complication rate(OR=0.73, 95% CI:0.56-0.95, P<0.05) and lower mortality(OR=0.63, 95% CI:0.44-0.91, P<0.05). However, no significant differences existed in mortality, readmission rate and re-operation rate between the two groups.

CONCLUSIONSEnhanced recovery after surgery programme in perioperative management of pancreaticoduodenectomy is safe and effective. But due to the medium quality of the literature. This still need more rigorously designed RCTs to prove the safety and efficiency of ERAS programme for the patients undergoing pancreaticoduodenectomy.