1.Discussion about security management of HIS
Yi ZHANG ; Guanyuan YU ; Huayong JIANG
Chinese Medical Equipment Journal 1993;0(05):-
With the rapid development of computer technology and informatization of the society,hospital network security and reliability becomes more and more important.According to HIS maintenance in our hospital,this paper discusses security measures in hospital from such aspects as system security,data security,network security,and security management.
2.The Radiotherapy of Pulmonary Carcinoma by X-ray Knife and CT Followed up
Dapeng LIU ; Huayong JIANG ; Wu QI ; Yanyan WANG ; Yubo BI
Journal of Practical Radiology 2000;0(12):-
Objective To investigate the value of X-ray Knife in the stereotaxis radiotherapy of lung cancer.Methods 52 cases with pulmonary carcinoma were treated with X-ray knife,before and after that,general radiotherapy was applied.After whole radiotherapy,2 or 3 months later,all patients were followed by CT scan.The changes of tumor and clinical appearances were compared before and after therapy.The curative effect was estimated according to clinical appearances and CT findings.Results 6 patients were complete response(11.5%) ,29 patients were partial response(55.8%) and 13 patients were no changes or reduced less than 50%.The total responsive rate was 92.3%.Conclusion The treatment of lung cancer with X-ray Knife can give tumor accuracy high dosage irradiation.The short term therapeutic effectiveness is significant and safe on clinical.
3.Position modification and actual radiation dose in parotids for head and neck cancers treated with TomoTherapy
Huayong JIANG ; Yongqian ZHANG ; Yadi WANG ; Weidong XU ; Junmao GAO ; Fuli ZHANG ; Bo YAO
Chinese Journal of Radiological Medicine and Protection 2014;34(11):845-849
Objective To analyze the impact of parotid's position and volume changing on radiation dose for head and neck cancer treated with TomoTherapy.Methods Totally 12 patients with head and neck cancer were treated with TomoTherapy.Before the treatment,the dose distribution was recalculated with MVCT images,which would obtain the parameters of position,volume and actual radiation dose for parotids.Results The volume of parotids in Plan2 was significantly lower than in Plan1,and the percentage reduction was 29.06% and 31.78% for left and right parotid,respectively (Z =6.77,3.06,P < 0.05).Distance between the COM (center of mass) of parotids and the midline of body was significantly smaller in Plan2 than in Plan1,and the percentage reduction was 6.72% and 6.19% (t =5.14,5.80,P < 0.05) at left and right side,respectively.Average dose and V26 for both parotids were higher than those in Plan1,increasing by an average of 37.74%,25.08% (Z =-6.03,-5.31,P < 0.05) for left parotid and 30.45%,19.33% (Z =-5.43,-3.26,P <0.05) for right parotid,respectively.Conclusions The actual radiation dose to parotids was significantly increased during the radiation therapy for patients with head and neck cancer.There was a linear correlation between the decrease of distance between the COM of parotids and the midline of body and the percentage increase of parotids' radiation dose.No correlation between the reduction of parotids' volume and dose to parotids.In order to reduce the parotids' radiation dose,modification of treatment plan at the appropriate time is essential.
4.Construction and application of clinical microbiology laboratory data management expert system
Xuefeng LIN ; Huayong YING ; Xiaojun CHEN ; Danying JIANG ; Bingyong WANG ; Jing CHEN
Chinese Journal of Clinical Infectious Diseases 2016;9(2):161-167
Objective To introduce the construction and application of clinical microbiology laboratory data management expert system.Methods Firstly, the process management was introduced to clinical microbiology laboratory. Then the characteristics of data on each node of work process were analyzed, and SQL Server data table was created as the knowledge base of the expert system.Finally, VB6.0 was used to compile the knowledge acquisition module, reasoning desktop module and input/output interface procedures to finally construct the expert system.Rates of defect report, errors in bacterial identification and drug sensitivity test, delay in culture results reporting and average delayed days were compared before and after the application of the expert system.Results The expert system could be used for data management in process nodes like sample reception, information collection and input, bacteria culture medium selection, bacterial identification and drug sensitive test, interpretation of drug sensitivity results, comprehensive evaluation in bacterial identification and drug sensitivity results, report of negative result, report of positive result, blood culture, Mycoplasma culture, time limit of detection, and nosocomial infection indicators.No defect report was found after the application of expert system; rate of errors in selection of drug sensitivity test medium was reduced from 0.81% ( 31/3 836 ) in 2012 to 0.02%(1/5 433) in 2014;rate of delay in culture results reporting was reduced from 1.78% (320/17 983) to 1.18%(232/19 692), and the average delayed days was also reduced (3.8 d vs.3.2 d).Conclusion Clinical microbiology laboratory data management expert system can improve work efficiency and reduce errors, which can enhance the overall management of laboratory and the quality of clinical service.
5.The impact of image-guided radiation therapy on treatment of cervical cancer
Na LU ; Zongkai ZHANG ; Yadi WANG ; Fuli ZHANG ; Huayong JIANG ; Diandian CHEN
Chinese Journal of Radiation Oncology 2021;30(1):81-85
Objective:To evaluate the effect of radical image-guided radiotherapy (IGRT) on the target dose in cervical cancer and investigate the appropriate application mode.Methods:Twenty patients with cervical cancer treated with helical tomotherapy (HT) in Seventh Medical Center of PLA General Hospital from 2012 to 2016 were selected. A megavoltage CT (MVCT) scan was performed before each treatment. The obtained MVCT images were used for dose parameter in the adaptive module of HT to obtain the actual dose (Plan 1) and the non-image-guided dose parameter was simulated (Plan 2). Each single dose distribution and the corresponding fused CT images were transferred to the software Mimvista 6.5 to obtain the total radiation dose parameter by dose superposition.Results:The motion of CTV, uterus and GTV in Plan 2 was significantly larger than that of Plan 1(all P<0.05), and the largest changes were seen in the ventrodorsal and uterine direction. The V 45Gy, V 50Gy, D 98% and D mean of CTV and uterus and V 50Gy of GTV in Plan 2 were significantly decreased compared with those in Plan 1(all P<0.05). The left-right motion of Plan 1 was negatively correlated with D 2% and D 98% of CTV and uterus (both P<0.05). The head-foot motion was negatively associated with V 45Gy and V 50Gy of GTV (both P<0.05). The ventrodorsal motion was negatively correlated with D 98% of uterus ( P<0.05). The left-right motion of Plan 2 was negatively correlated with D 2% of CTV and V 50Gy of uterus (both P<0.05). The head-foot motion was negatively associated with D 98% of CTV, and D 98%, D mean, V 45Gy and V 50Gy of uterus (all P<0.05). The ventrodorsal motion was negatively correlated with D 98% of CTV, D 98%, D mean, V 45Gy and V 50Gy of uterus, and D mean and V 45Gy of GTV (all P<0.05). Conclusions:In intensity-modulated radiotherapy for cervical cancer, the uterine body displacement is large and the low CTV area is mainly located in the uterine body. IGRT can significantly reduce the dosimetric deviation induced by organ movement.
6.Impacts of bladder and rectum filling status on their dosimetric parameters in helical tomotherapy for cervical cancer
Zongkai ZHANG ; Yadi WANG ; Fuli ZHANG ; Na LU ; Bo YAO ; Huayong JIANG
Chinese Journal of Radiation Oncology 2018;27(5):513-516
Objective To analyze the changes in volume and the planning volume of the bladder and rectum during helical tomotherapy (HT) treatment for cervical cancer,and to evaluate the impacts of bladder and rectum filling on their dosimetric parameters.Methods Twenty patients with cervical cancer who received HT in our hospital from 2012 to 2016 were enrolled as subjects.Before treatment,megavolt computed tomography (MVCT) and registration of planning CT images were preformed to recalculate the dose distribution,delineate the target volume,and measure the volume and position of the bladder and the rectum.Each MVCT image and the corresponding single dose were obtained by dose reconstruction using the Planned Adaptive module in HT planning workstation.The fused MVCT images and the corresponding single dose for each MVCT were loaded to MIM Maestro software 6.0 for dose stacking.The obtained total radiation dose was compared with that obtained by kilovolt CT.Between-group comparison was made by paired t-test or analysis of variance.Results If the volume change in the bladder was more than 400 ml or the rate of volume change was higher than 60%,the displacements of the bladder centroid toward the foot and dorsal sides were significantly increased;the Dmean and V50 were significantly increased (P<0.05).If the volume change in the rectum was more than 30 ml or the rate of volume change was higher than 30%,the displacements of the rectum centroid toward the head and ventral sides were significantly increased;the V45 and V50 for the rectum were significantly increased (P<0.05).Conclusions Although the bladder filling status has little effect on the radiation dose to the bladder,the volume change or the rate of volume change should be no more than 400 ml or 60%,respectively.Moderately filled bladder is recommended for positioning and treatment,which achieves satisfactory repeatability of the treatment.A volume change of more than 30 ml or a rate of volume change of higher than 30% can result in an increase in the dose to the rectum.Empty rectum can effectively reduce the dose to the rectum.
7.Different Anesthesia and Sedation Depths of BIS-guided Closed-loop Target-controlled Infusion on Perioperative Th1/Th2 Balance in Elderly Patients Undergoing Laparoscopic Radical Gastrectomy
Huayong JIANG ; Weilong LAO ; Guozhong ZHOU ; Qiliang SONG ; Zongming JIANG ; Weisheng YU ; Zhonghua CHEN
Cancer Research on Prevention and Treatment 2022;49(5):444-447
Objective To investigate the effect of BIS-guided closed-loop target-controlled infusion on perioperative Th1/Th2 balance in elderly patients undergoing laparoscopic radical gastrectomy under different anesthesia and sedation depths. Methods We applied random number table method to divide 73 elderly patients undergoing elective laparoscopic radical gastrectomy into BIS closed-loop target-controlled infusion group with BIS value of 55(group H,
8.Clinical distribution and drug resistance analysis of hospital infection en-terococci
Danying JIANG ; Xuefeng LIN ; Bingyong WANG ; Jing CHEN ; Huayong YING
China Modern Doctor 2015;53(35):99-102
Objective To investigate the clinical isolation situation and drug resistance features of enterococcal bacteria in order to provide reference for the clinical rational use of antibacterial agents and infection control. Methods A total of 1220 strains of enterococcal bacteria that induced hospital infection were analyzed retrospectively. Walk Away 96 automated microbial analyzer was used for strain identification and drug sensitive test. MIC was used for screening high-level aminoglycoside resistant strains. WHONET 5.6 was used for data analysis. Results A total of 1220 strains of enterococci were detected, including 675 strains of enterococci faecalis, accounting for 55.3%, and 445 strains of ente-rococci faecium, accounting for 36.5%. Enterococcal bacteria mainly distributed in clinical urine specimens, accounting for 57.5%. The total drug resistance rate of enterococci faecalis was high and the drug resistance rates to penicillin, ampicillin, ciprofloxacin and levofloxacin were all higher than 90%, which were significantly higher than those of the enterococci faecium (<17%). The drug resistance rate of enterococci faecalis to quinupristin/dalfopristin was 100.0%and that of enterococci faecium was 12.6%. For both types of bacteria, no strain resistant to vancomycin was found, but 3 strains of enterococci faecalis were resistant to linezolid. The screening rates of enterococci faecalis for high-level gentamicin drug resistant strains and high-level streptomycin resistant strains were 54.1% and 27.3% respectively while those of enterococci faecium were 58.2% and 56.9% respectively. Conclusion The drug resistance situation of enterococcal bacteria to common antibacterial drugs is not optimistic, and the monitoring of clinical distribution and drug resistance situation of enterococcal bacteria is of important guiding significance to the clinical treatment of entero-coccal bacterial infection.