1.Comparison of DK crush with classical crush technique with drug-eluting stents for the treatment of coronary bifurcation lesions from DKCRUSH-1 study.
Shao-liang CHEN ; Jun-jie ZHANG ; Fei YE ; Yun-dai CHEN ; Shu-zheng LÜ ; Huaycheem TAN ; Tejas PATEL ; Kawajiri KENJI ; Israel TAMARI ; Shou-jie SHAN ; Zhong-sheng ZHU ; Song LIN ; Nai-liang TIAN ; Xiao-bo LI ; Zhi-zhong LIU ; Michael LEE ; Meng WEI ; Ya-wei XU ; Zheng-bai YUAN ; Jun QIAN ; Xue-wen SUN ; Song YANG ; Jin-guo CHEN ; Ben HE ; Suji SUMIT
Chinese Journal of Cardiology 2008;36(2):100-107
OBJECTIVETo determine independent factors correlated with clinical effects of DK crush and classical crush technique with drug-eluting stents on bifurcation lesions.
METHODS311 patients with bifurcation lesions were randomized to classical (C, n = 156) or double kissing (DK) crush (n = 155) stent implantation group. The primary endpoints included major adverse cardiac events (MACE).
RESULTSFinal kissing balloon inflation (FKBI) success rate was 76% in C and 100% in DK groups (P < 0.001). DK crush procedure was characterized by lower unsatisfactory FKBI rate (27.6% vs.6.3%, P < 0.01). Clinical follow-up was available in 100% and angiographic follow-up in 82% patients. The overall restenosis rate was 32.3% in C and 20.3% in DK groups (P = 0.01), respectively. Cumulative 8-month MACE was 35.9% in without-FKBI and 19.7% in with-FKBI sub-groups, and 11.4% in DK group (P = 0.02). The incidence of stent thrombosis was 3.2% in C group (5.1% without vs. 1.7% with FKBI) and 1.3% in DK group (P > 0.05). The predictive factors of MACE included minimal side branch stent lumen diameter and lack of DK crush technique.
CONCLUSIONDK crush technique is an alternative of double stenting techniques in terms of improvement of restenosis and clinical outcomes.
Aged ; Angioplasty, Balloon, Coronary ; methods ; Coronary Artery Disease ; therapy ; Coronary Stenosis ; therapy ; Drug-Eluting Stents ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Stents
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