Objective To explore the relationship among thyroid stimulating hormone level and sex hormone level,blood lipid level and insulin resistance in patients with polycystic ovary syndrome. Methods From February 2014 to February 2017,eighty cases with polycystic ovary treated in the People's Hospital of Longhua,Shenzhen were selected as the research object. The clinical data of all patients were collected to check the indexes of thyroid function,lipid metabolism,glucose metabolism,and sex hormone related indexes,and the insulin resistance index (HOMA-IR) was calculated according to the related indexes of glucose metabolism. The patients were divided into group according to the level of thyrotropin,group A (thyrotropin＜2. 5mIU / L),group B (2. 5mIU / L＜thyrotropin＜4. 0mIU / L) and group C (thyrotropin＞4. 0mIU / L). According to the patient's insulin resistance index,the patients were divided into IR group and non IR group. According to the blood lipid metabolism index,the patients were divided into abnormal blood lipid group and non lipid abnormality group. The levels of thyrotropin and sex hormone related indexes were compared in different groups, and the correlation between thyrotropin level and various indexes was analyzed. Results The differences in body mass index ((23. 3±4. 2) kg/m2vs. (23. 8±3. 5) kg/m2vs. (25. 6±5. 2) kg/m2),luteinizing hormone((11. 9±1. 1)U/L vs. (11. 7±1. 2)U/L vs. (9. 5±1. 0)U/L),low density lipoprotein cholesterol ((2. 4±0. 9) mmol/L vs. (2. 7 ±0. 7) mmol/L vs. (2. 9±0. 8) mmol/L),high-density lipoprotein cholesterol ((1. 5±0. 4) mmol/L vs. (1. 5 ±0. 5) mmol/L vs. (1. 3±0. 2) mmol/L),triglyceride ((1. 1±0. 8) mmol/L vs. (1. 5±0. 9) mmol/L vs. (1. 8 ±0. 7) mmol/L),and apolipoprotein A ((1. 8±0. 5) mg/L vs. (1. 7±0. 4) mg/L vs. (1. 5±0. 3) mg/L) among group A,B and C were statistically significant (F＝8. 456,9. 587,11. 245,10. 784,10. 847,10. 214,P＜0. 05). The serum TSH concentration in group IR was significantly higher than that in non IR group (( 3. 1 ±1.1) mU/L vs.(2.3±0.8) mU/L) (t＝3.551,P＜0.05).The serum LH concentration in group IR was significantly lower than that in non IR group((9. 4±1. 1)U/L vs. (11. 2±2. 1)U/L) (t＝3. 739,P＜0. 05). The level of TSH in dyslipidemia group was significantly higher than that of non dyslipidemia group(( 3. 2 ± 1. 3) mU/L vs. (2. 4±1. 1) mU/L) (t＝3. 551,P＜0. 05),and the level of LH in dyslipidemia group was significantly lower than that of non dyslipidemia group((9. 3±1. 6)U/L vs. (11. 6±2. 4)U/L) (t＝4. 709,P＜0. 05). The TSH level in patients with polycystic ovary syndrome was positively correlated with body mass index, three acylglycerol,low density lipoprotein cholesterol and insulin resistance index( r＝0. 272,0. 317,0. 364,0. 227) ( P＝0. 015,0. 004,0. 003,0. 043),and there was a negative correlation with luteinizing hormone and high-density lipoprotein cholesterol(r＝－0.616,-0.254) (P＝0.000,0.034).Conclusion Hyperthyroidism in patients with polycystic ovary syndrome is associated with abnormal blood lipid,abnormal sex hormone levels,and insulin resistance.

Objective To explore the nursing program of large dose hormone therapy for the treatment of uveitis patients , and to provide the reference for clinical nursing program .Methods A total of 196 patients with uveitis were randomly divided into observation group and control group with 98 cases 136 eyes each group by the random number table method .All patients were treated with high-dose hormone therapy .The control group received routine nursing care , while the observation group was given comprehensive nursing intervention measures.The clinical efficacy and recurrence rate of two groups were compared .Results After treatment, the total effective rate of observation group was 90.44%, and it was 89.71%in the control group (χ2 =0.041,P>0.05).Over 1 year of follow-up, the recurrence rate in the observation group was 5.15%, while it was 30.88%in the control group, and the recurrence rate of the observation group was significantly lower than that of the control group (χ2 =30.381,P<0.05).Conclusions During the process of high dose hormone therapy of uveitis patients , rigorous observation and comprehensive nursing interventions can help clinical treatment effect, reduce the recurrence rate of uveitis , and is worth of further application .