1.Clinical effects of oxytocin induced labor route
Huaping CHEN ; Limin CHEN ; Lifei XIA
Chinese Journal of Biochemical Pharmaceutics 2017;37(9):293-294
Objective To study and analyze the clinical effects of different oxytocin induced labor routes. Methods From March 2015 to September 2016, 100 pregnant women who needed induced labor or induced oxytocin were selected in our hospital. They were randomly divided into the control group and the study group, with 50 patients in each group. The control group with traditional infusion method, given intravenous indwelling needle puncture method in patients with the study group, select the vein elastic and straight, thick, pay attention to the reasonable sealing, adjust the dropping speed according to the patients with uterine contraction. The infusion speed, safety and accuracy of the patients in the study group and the control group were compared and analyzed. Results After the corresponding administration route, there were 0 patients with drop velocity errors in the study group, and 12 patients in the control group. In the control group, the rate of drop error was 24%, which was significantly higher than that of the study group (0%), with statistical difference (P<0.05). Among the patients in the study group, the number of blocked tubes was 1, the probability was 2%, the rate of subcutaneous infiltration was 4%, and the incidence of needle prolapse was 0%. In the control group, the rate of subcutaneous exudate was 10%, the probability of blockage was 8%, and the incidence of needle prolapse was 6%. The average time spent by the study group on regulation of drip speed was (8.09 ±2.10) s, significantly shorter than that of the control group (78.90 ± 9.20) s, with statistical difference (P<0.05). Conclusion Intravenous catheter infusion of oxytocin administered with traditional delivery mode, simple operation, can significantly reduce the drop speed error probability, the clinical effect is ideal, has the meaning of promotion.
2.Goserelin combined with marvelon in treatment of patients with endometriosis
Lichai WANG ; Jianhong CHEN ; Huaping SHI
Chinese Journal of Endocrine Surgery 2015;(5):415-418
Objective To investigate the effect of goserelin combined with marvelon in treatment of en -dometriosis(EM)and its effect on estrogen levels .Methods 120 EM patients were randomly divided into the ob-servation group(60 cases)and the control group(60 cases)according to the digital table.Two groups underwent laparoscopy .3.6 mg sustained release goserelin was injected subcutaneously from the anterior abdominal wall once every four weeks on the first time of menses recovery .The treatment continued during the following six months.The observation group were treated with marvelon on the basis of this , 1 tablet each day, 21 days of con-tinuous treatment and then began to take medicine on the 5 th day of the next menstruation during the following six months.The two groups were followed up for two years .The level of luteinizing hormone(LH), follicle-stimula-ting hormone(FSH)and estradiol(E2), the cumulative pregnancy rate, recurrence rate and peri menopausal sta-tus of the two groups were observed before and after treatment .Results The total effective rate was 96.67%and 83.33%respectively for the observation group and the control group .The difference had statistical significance (P<0.05).The level of E2, FSH, and LH at 1 month, 3 months, 6 months after treatmnet was lower than that before treatment(P<0.05).The level of E2, FSH, LH of two groups had no statistical difference (P<0.05). The cumulative pregnancy rate of the observation group was higher than that of the control group while the recur -rence rate was lower than that of the control group ( P<0.05 ) .The perimenopausal symptom score ( Kupperman score)of the two groups had no significant difference (P>0.05).Conclusion Goserelin combined with marvel-on can effectively improve the effect of laparoscopic surgery in treatment of endometriosis , lower estrogen level , improve patients'pregnancy rate , and reduce the recurrence rate .
3.Template synthesis based on bacterial cellulose
Weili HU ; Shiyan CHEN ; Huaping WANG
Chinese Journal of Tissue Engineering Research 2009;13(8):1597-1600
Bacterial cellulose (BC) is a new kind of natural biological nano-materials which displays unique physical, chemical and mechanical properties. It has high bioactivity, good biocompatibility, and biodegradability. BC fiber has a nanoporous structure and certain nano-pore size distribution, and a large number of nanopores can be used as a "template". BC can be used as a template to synthesize nano-composite materials with three-dimensional network structure through biomimetic synthesis. BC can also be used as a template to stabilize and disperse the polymers which are easily assembled into a cluster or bundle in the ultra-fine fiber network structure. The BC template could be removed in order to change or optimize the properties of the composite material. The process can make use of the synergy between the BC template and inorganic materials to make a new type of hollow molecular sieve. It can synthesize a variety of nanoscale metal oxides with the hollow network. The present study of template svnthesis based on BC is introduced in this paper.
4.Investigation and analysis of the subjective life quality of hospitalized children
Huaping LU ; Yanhua FU ; Linlin CHEN
Chinese Journal of Practical Nursing 2013;(2):58-60
Objective To investigate the subjective life quality of hospitalized children and analyze its influencing factors for improving their life quality.Methods 48 hospitalized children who were admitted between May to August 2011 were investigated in convenience using inventory of subjective life quality (ISLQ).Results Patients investigated had a higher score than the national norm on Family Life Dimension.The satisfaction level of 20% ~ 30% children were below the average on Family Life and other eight dimensions,the cognitive components of 16 cases (33.3%) and emotional component of 11 cases (22.9%) were below the average.15 cases (31.3%) were not satisfied with their subjective quality of life.Female patients had higher scores than male patients on peer exchanges,body feelings and subjective quality of life satisfaction; the satisfaction level of experience depression for rural children was lower than urban children.Conclusions The subjective life quality of vast majority of hospitalized children is about the general level,but some patients still experience serious anxiety,depression and other negative psychological emotion.Nurses should guide the patients positively and specially,considering the influence of their gender and living places while providing caring.Based on the health education of patients and their family,we promote them to face the disease.
5.Curative effect analysis of neuroendoscopic surgery via superior frontal sulcus in the treatment of ;hypertensive intracerebral hemorrhage
Liang TAO ; Zhibiao CHEN ; Huaping ZHANG
Chinese Journal of Postgraduates of Medicine 2016;39(5):393-396
Objective To investigate the surgical technique and the curative effects of neuroendoscopic surgery via superior frontal sulcus in the treatment of hypertensive intracerebral hemorrhage. Methods The clinical data of 63 patients with hypertensive intracerebral hemorrhage were analyzed retrospectively. Thirty-one of them were treated by neuroendoscopic surgery via superior frontal sulcus(neuroendoscopic surgery group), and 32 of them were treated by mini- invasive drainage (conventional therapy group). All of them were followed up for 6 months, and were assessed by the activity of daily living (ADL) scale. Results After treatment, all patients reviewed CT. The clear rate of hematoma in neuroendoscopic surgery group was 86.0%, in conventional therapy group was 23.3%, and there was significant difference (P<0.05). There were one death case in neuroendoscopic surgery group and 2 death cases in conventional therapy group. The survival patients were followed up for 6 months .The rate of better prognosis in neuroendoscopic surgery group was 83.3%(25/30), in conventional therapy group was 53.3%(16/30), and there was significant difference (P<0.05). Conclusions The surgical technique of neuroendoscopic surgery via superior frontal sulcus in the treatment of hypertensive intracerebral hemorrhage is safe and effective.
6.Analysis of Xiaogan city grass-roots county hospital scientific paper output
Tao CHEN ; Lixia FU ; Wensheng ZHU ; Huaping JING ; Min CHEN
Chinese Journal of Medical Science Research Management 2015;28(2):197-199,封4
Objective primary hospitals at the county level in xiaogan City 17 years for the production of scientific papers in qualitative and quantitative statistical analysis,summary of research progress and existing problems in county hospitals,and provides references for research management in local hospitals.Methods Wanfang medicine network included in 1998-2014 year published Xiaogan city 7 county hospital as the object;All biomedical scientific papers published as the first author to statistical analysis.Results 7 County Hospital of xiaogan City 17-year total output articles 1909,General journals 1273articles(66.68% per cent),Core journal 636 papers (33.31% per cent).Hanchuan city people's Hospital total the largest number of papers;total 544 articles (28.50% total),yingcheng hospital quality highest core journal papers and the highest proportion;total 186 (proportion of the total core thesis 29.25 %),minimum quantity and quality of outputs anlu city people's Hospital,only 15 articles in periodicals of General The core journals and 2 papers (0.89% of the total number of accounts for the paper,core paper accounted for 0.31% of the total).On the whole 2006-2009 published papers began to gradually slow growth,The number 2010-2014 entered the stage of rapid growth,but the core papers for slow growth.Conclusions xiaogan city grass-roots scientific articles in recent years in county hospitals are generally presented a trend of rapid growth,but the quality of growth is relatively slow,output quantity and quality distribution imbalances between hospitals.
7.Substance P stimulates differentiation of mice osteoblast through up-regulating the expression of Osterix
Haibiao SUN ; Qiang LIU ; Minfeng GUO ; Huaping ZHANG ; Junchang CHEN
Journal of Xi'an Jiaotong University(Medical Sciences) 2009;30(6):716-719
Objective To study the molecular pathway of osteoblastic differentiation induced by substance P (SP), a neurotransmitter. Methods Mesenchymal stem cells were isolated and cultured, and treated with SP or its receptor (NK1) antagonist to induce osteoblastic cell differentiation, respectively. Alkaline phosphatase activity was determined; Osterix gene expression was detected by RT-PCR after 1-2 weeks for three times. The data of each culture condition were analyzed using SPSS12.0 statistical software to determine whether the differences between conditions were significant. Results After 4-5 days' culture, bone marrow stromal cells became spindle-shaped, triangular or polygonic. They covered the plate surface, formed extensive cell sheets in each group after 11-12 days of culture, and then induced differentiation to osteoblast. SP up-regulated the important transcription factor Osterix gene expression significantly (P<0.05). Conclusion The up-regulation of Osterix gene expression by SP may stimulate osteoblastic cell differentiation. SP's regulation depends on its receptor NK1.
8.Effect of Chinese Daoyingong method on knee osteoarthritis
Qi CHEN ; Xiaoyun MENG ; Huaping DENG ; Hongsheng ZHAN ; Chaoqing GUO
Modern Clinical Nursing 2014;(10):43-46
ObjectiveTo explore the effect of Chinese Daoyingong method on knee osteoarthritis.Methods Eighty patients with knee osteoarthritis were randomly divided into the experiment group and control group in equal number.The control group was given the routine medicine combined with Chinese fumigation and the experiment group was treated with Chinese Daoyin method beside the treatment in the control group.The two groups were compared in terms of the score on visual analog scale of pain and the score on knee function before and after treatment.Results The visual analog scale of pain in the experiment group was significantly lower than that in the control group after intervention and the score on knee function was significantly higher than that of control group (P<0.001). Conclusion The intervention with Chinese Daoyingong method plus routine medication and Chinese herbal fumigation is effective in the treatment of knee osteoarthritis.
9.The Comparative Analysis on CT and X-ray Film in Diagnosis of Transparent Foreign Body in Trachea and Bronchus
Haijun ZHENG ; Haijun ZHOU ; Zhongxiong HUANG ; Jin GAO ; Huaping CHEN
Journal of Practical Radiology 2001;0(01):-
Objective To study the CT signs of bronchotracheal transparent foreign body and its diagnostic value.Methods The X-ray and CT findings of bronchotracheal trasparent foreign body in 46 cases were analysed comparativly.Results Among 46 cases,9 cases of trachea foreign body,13 cases of right bronchial foreign body,7 cases of left bronchial foreign body,2 cases of both sides of bronchial foreign body were showed directly by CT,and 8 cases of right bronchia foreign body,6 cases of left bronchia foreign body,1 case of both sides of bronchia foreign body showed indirectly on CT,the sensitivity was 100 percent,while the foreign body and its anatomical location could not be showed on X-ray film,but the indirect signs just like pulmonary emphysema,obstructive pulmonitis and drowned lung etc,could be showed by X-ray films in 34 cases.In another 12 cases were negative,the sensitivity was 73.9 percent.Conclusion The transparent foreign body can not be showed but indrect signs by X-ray film;While CT scan can not only shows the anatomical location of foreign body,but also the shape and size of the foreign body,it offers more information than X-ray films and has important refering value to clinicians to take out the foreign body.
10.The Application of the Super-short Time Exposure of the DR Adjustable Control in Radiography of the Infant Chest
Renhua ZHANG ; Bohong DENG ; Haijun ZHENG ; Huaping CHEN
Journal of Practical Radiology 1996;0(04):-
Objective To explore the applied value of the super-short exposure time of the DR adjustable control in radiography of infant chest.Methods 100 chest radiographic films of infant in adjustable control group and fixed control group respectively were selected randomly.The quality of all films was evaluated by 4 technicians in charge in 4 grades(A,B,C and waste)and the detective rate of the tiny parts of the images was also evaluated.Results DR adjustable control:the rate of grade A,B,C and waste was 70%,20%,10% and 0% respectively.DR fixed control:the rate of grade A,B,C and waste was 42%,41%,15% and 2% respectively.The detective rate of tiny parts was 100% and 90% in DR adjustable control group and DR fixed control group respectively.Conclusion DR adjustable control chest film in infant is better than DR fixed control in image quality.DR adjustable control system is good for radiographic diagnosis.