1.Development and application of fixed ruler for simulated locator
Guohua LU ; Huankun WANG ; Ke LI
Chinese Medical Equipment Journal 2017;38(4):48-50
Objective To develop a fixed ruler for the simulated locator to measure the distance between human organs.Methods Analyses were carried out on the problems of the existing measures of the simulated locator and clinical requirements,and then the matching of the ruler with the locator and etc were explored.The structures of the fixing hole and slots were determined,and the ruler base was selected.The ruler was composed of an organic glass plate with multi slots and multi cylindrical copper wires.Results At the isocenter of the locator,the fixed scale values of the ruler equaled to those of the ruler on the screen,and the values for multi point distances could be obtained with the fixed ruler and stored in medical image.Conclusion The fixed ruler measures the distance between human organs simply and accurately,and lays a foundation for the development of likely product.
2.The action of radial surgery in the treatment of large cerebral metastatic carcinoma
Huankun WANG ; Suyuan TAN ; Guohua LU ; Yanmei ZHAO ;
Chinese Journal of Tissue Engineering Research 2002;6(2):300-301
Objective To investigate the therapeutic effect of radial surgery in large cerebral metastatic carcinoma. Methods Adopt three dimensional oriented radial surgery to 15 patients with the biggest diameter of more than 35mm. Observe the variation of clinical symptoms and analysis the change of CT image. Follow up the survival time, complications and the cause of death at the same time. Results Most of the patients got prominent improvement in symptoms. But the imaging change of carcinoma focus was a slow course comparatively. The survival rate in 1 year was 26% . Conclusion Radial surgery is an effective, simple and safe method in the treatment of large cerebral metastatic carcinoma. It has a good control rate with only slight complications.
3.Development and effectiveness evaluation of time-resolved fluoroimmunoas-say kit for detection of Schistosoma japonicum
Qingdong MENG ; Yan WANG ; Wenqiao SUN ; Shoulei REN ; Bo XIN ; Pengfei ZHU ; Kangyan LI ; Huankun LIANG ; Licheng ZHANG
Chinese Journal of Schistosomiasis Control 2017;29(1):64-67
Objective To develop a kit of time?resolved fluoroimmunoassay(TRFIA)for detection of Schistosoma japonicum protein SjP38,and evaluate its effectiveness. Methods The anti 9G7 SjP38 monoclonal antibody was used as the capture anti?body coated with 96?hole plate,and the Eu3+labeled 1A6 monoclonal antibody was used as the detection antibody to establish the TRFIA SjP38 kit. In addition,the accuracy,sensitivity,precision,stability and coincidence rate to pathogenic diagnosis of the kit were evaluated. Results This established kit possessed high accuracy,wide linear range from 2 to 1 250 ng/ml,high sensitivity with the minimum detectable concentration of 0.14 ng/ml,and good precision(the coefficient variation of the intra?and inter?assay were 3.6%to 4.6%and 5.1%to 6.7%,respectively). The stability tests showed that the reagents could be stable for six months at 4℃,7 d at 37℃. The positive and negative corresponding rates to the pathogen detection method were 95%and 100%respectively. Conclusion All the performance and detection indicators of the kit have reached the requirements of clinical test,but its clinical application still needs further validation.
4.Study on the size difference of bilateral axillary vein in adults
Huankun LOU ; Yuju REN ; Minglang WANG ; Zheng DONG ; Luoqing WANG ; Rongyuan CAO ; Liming SUN ; Yilian WANG
Chinese Journal of Primary Medicine and Pharmacy 2020;27(10):1158-1162
Objective:To study the size difference of bilateral axillary vein in adults, and to provide basis for the design of interventional surgical treatment.Methods:From December 2017 to December 2018, 145 inpatients (117 cases of hypertension, 28 cases of heart failure) and 87 healthy volunteers were selected from the Second People's Hospital of Lianyungang as study objects.The size of bilateral axillary vein of each study object was measured and the difference was statistically analyzed.Results:Among the 232 subjects, the dominant hand was the right hand, accounting for 95.7% (222/232). There were no statistically significant differences in the size of left and right axillary veins (all P>0.05). There were no statistically significant differences in the other indicators except age between the two groups (all P>0.05). The diameter of axillary vein was (0.67±0.15)cm in male and (0.53±0.13)cm in female, the difference is statistically significant( P=0.000). In the healthy control group, the dominant, non-dominant and large cross-sectional areas were (0.54±0.17)mm 2, (0.54±0.15)mm 2, (0.60±0.16)mm 2, respectively, which in the hypertension group were (0.55±0.14)mm 2, (0.54±0.14)mm 2, (0.59±0.14)mm 2, respectively, which in the heart failure group were (0.54±0.16)mm 2, (0.56±0.19)mm 2, (0.59±0.1)mm 2, respectively, there were no statistically significant differences among the three groups (all P>0.05). Conclusion:The difference is not obvious in the size of bilateral axillary vein, and there is no correlation between the size of bilateral axillary vein and dominant hand.The size of axillary vein in adults of different genders is different, and the size of axillary vein can be estimated by the gender of subjects, but not by the dominant hand or other data.