1.Application and comparison of PET/CT, contrast enhanced CT and MRI in the clinical manage-ment of pancreatic cancer
Chinese Journal of Nuclear Medicine and Molecular Imaging 2017;37(10):654-659
Recently, either in the field of preoperative differential diagnosis and staging, or in the diagnosis of postoperative recurrence and distant metastasis, the application of PET/CT in pancreatic cancer attracts more and more attention. Combining the precise anatomical information of CT with the functional metabolic information of PET, 18 F-FDG PET/CT can not only accurately locate the T staging, but also de-tect regional or distant metastasis, which make the early diagnosis and staging of pancreatic cancer easier. This review summarizes the recent progress of PET/CT imaging in the clinical application of pancreatic cancer by comparison of the contrast enhanced CT and MRI, trying to analyze different imaging modalities in clinical management of pancreatic cancer.
2. The application of artificial dermis in repairing partial fingernail bed defect
Shaohua LIU ; Zhanbei MA ; Hetong YU ; Liang MA ; Yuechuang LIANG ; Yu WU ; Dongyue LI ; Chong NAN ; Huanhuan ZHAO ; Xiaowei REN ; Lie HUO
Chinese Journal of Plastic Surgery 2018;34(11):955-958
Objective:
To explore the clinical effect of artificial dermis on partial nail bed defects.
Methods:
From May 2013 to September 2016, 16 cases of 21 fingers with partial nail bed defect and bone exposure received primary repair with artificial dermis after debridement. Then the outer dressing was changed 3 days after the operation, and the dressing was changed once every 3 to 5 days. The pink dermis like tissue was placed on the wound surface 2 to 3 weeks after the operation. The wound surface was naturally epithelialized.
Results:
All the fingers were survived after artificial dermis repair, and the fingertip surface of nail bed defect was epithelialized naturally and healed well. Postoperative follow-up was 5 to 16 months, with an average of 8.2 months. The growth of fingernails was smooth with symmetrical appearance, natural toughness, good adhesion between the nail body and the nail bed, and no pain or hyperesthesia at the tip. Results of curative effect evaluation showed excellent in 18 fingers, good in 3 fingers. Results of patient′s satisfaction with postoperative finger appearance showed very satisfactory in 13 cases and satisfactory in 3 cases.
Conclusions
The method of repairing partial defect of nail bed using artificial dermis is simple with minimal damage and a good clinical effect.
3.Effects of growth hormone co-treatment with progesterone-primed ovarian stimulation protocol on IVF outcomes in women with low prognosis
Jianeng ZHANG ; Huanhuan ZHANG ; Chong WANG
China Modern Doctor 2024;62(5):6-10
Objective To study the effect of growth hormone(GH)with progesterone-primed ovarian stimulation(PPOS)protocol on in vitro fertilization(IVF)outcomes among women with low prognosis.Methods This is a retrospective cohort study using propensity score matching(PSM)analysis.Women commencing their IVF between January2017 to December2021,with and without GH co-treatment,were reviewed.Results After PSM,76 pairs of women with low prognosis were included into analysis.Paired testing showed there is a statistical increase in transferable embryo(P<0.001)in the GH co-treatment group comparing with control group.No significant difference showed in retrieved oocyte number and metaphaseⅡ(MⅡ)oocyte rate,two-pronuclear(2PN)zygote rate on day1,high-quality embryo rate,or clinical pregnancy rate,neither in gonadotropin(Gn)requirement,duration or peak estradiol.Subgroup analysis results showed transferrable embryo rate on day3 rising among decreased ovarian reserve women(P=0.010).For women aged below 40,MⅡoocyte rate(P=0.010)and transferrable embryo rate on day3(P<0.001)increased in GH co-treatment group.Conclusions GH is suggested a beneficial impact on oocyte quality and transferrable embryos with PPOS protocol in IVF.Its adjuvant administration can be proposed as an optional therapeutic strategy in women with low prognosis.