Objective To analyze and discuss the source and epidemic disposition of human infection with avian influenza A(H10N8)virus. Methods Epidemiological surveys were used to collect related data and RT-PCR was applied to detect the specimens collected from cases,close contacts related exposure to live poultry markets. Data were analyzed descriptively. Results Three cases were discovered by surveillance on patients with severe pneumonia,two of the three died,but one in the hospital with the course over 6 months. All the three cases had histories of exposure to live poultry or related markets. Lower respiratory tract gargle aspirate samples of 3 patients were detected by Nanchang Municipal Center for Disease Control and Prevention (CDC) and Jiangxi Provincial CDC,and the results showed the influenza 2009pdmH1,H3,H5,H7,H9 subtypes negative. Specimen of patient 1 and 2 was positive for influenza A universal primers. Specimen of patient 3 was positive for H10N8 detected by Chinese National Influenza Center. All 33 close contacts of the patients were negative for H10N8 virus. Positive rate of the total poultry environmental specimens collected from the cases exposure markets was 5.19%. No new cases were found,after the prevention and control messages were implemented. Conclusion Three cases of H10N8 avian influenza virus infection province might be associated with exposure to live poultry market in Jiangxi.

Objective:To analyze epidemic trends of other infectious diarrhea in Jiangxi Province from 2017 to 2022, and explore the application of autoregressive integrated moving average (ARIMA) model in the prediction of the incidence of other infectious diarrhea in Jiangxi Province, providing reference for the prediction and prevention and control of other infectious diarrhea.Methods:To conduct a descriptive epidemiological analysis of other infectious diarrhea cases in Jiangxi Province from 2017 to 2022, and establish an ARIMA model to predict the number of other infectious diarrhea cases in 2023.Results:From 2017 to 2022, Jiangxi Province reported 204 842 cases of other infectious diarrhea. The annual average reported incidence rate was 74.32/100 000. The cases were reported in each age group with obvious seasonal characteristics of the main peak. There were two peak periods of incidence in winter and spring (from January to March) and in summer and autumn (from July to September) and the peak value was higher in winter and spring. All parameters of the model ARIMA (0,1,2)(2,1,0) 12 and ARIMA (1,0,0)(2,1,0) 12 were statistically significant ( P<0.05), and the minimum values of Bayesian information criterion were 13.83 and 9.12, respectively. The residual series were all white noise ( P>0.05); The predicted value of the model is in good agreement with the actual value, and the predicted trend is consistent with the actual trend. The model has a good prediction effect. Conclusions:The other infectious diarrhea occurred in 2017-2022 was still the first case of notifiable disease in Jiangxi Province. The prevention and control situation cannot be ignored. Disease monitoring and health education for families of children under 3 years of age and scattered children among key populations for prevention and control should be strengthened during the epidemic season. The ARIMA model can be used for short-term prediction and trend analysis of other infectious diarrhea outbreaks in Jiangxi Province.

OBJECTIVETo analyze and discuss the source and epidemic disposition of human infection with avian influenza A (H10N8) virus.

METHODSEpidemiological surveys were used to collect related data and RT-PCR was applied to detect the specimens collected from cases, close contacts related exposure to live poultry markets. Data were analyzed descriptively.

RESULTSThree cases were discovered by surveillance on patients with severe pneumonia, two of the three died, but one in the hospital with the course over 6 months. All the three cases had histories of exposure to live poultry or related markets. Lower respiratory tract gargle aspirate samples of 3 patients were detected by Nanchang Municipal Center for Disease Control and Prevention (CDC) and Jiangxi Provincial CDC, and the results showed the influenza 2009pdmH1, H3, H5, H7, H9 subtypes negative. Specimen of patient 1 and 2 was positive for influenza A universal primers. Specimen of patient 3 was positive for H10N8 detected by Chinese National Influenza Center. All 33 close contacts of the patients were negative for H10N8 virus. Positive rate of the total poultry environmental specimens collected from the cases exposure markets was 5.19%. No new cases were found, after the prevention and control messages were implemented.

CONCLUSIONThree cases of H10N8 avian influenza virus infection province might be associated with exposure to live poultry market in Jiangxi.

Animals ; China ; epidemiology ; Commerce ; Epidemics ; Humans ; Influenza A Virus, H10N8 Subtype ; isolation & purification ; Influenza in Birds ; epidemiology ; Influenza, Human ; epidemiology ; virology ; Pneumonia ; virology ; Poultry ; virology ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction