Objective To explore the preventive effect of pneumatic compression therapy combined with infrared irradiation against lower extremity deep vein thrombosis(DVT)in critically ill patients.Methods A total of 150 critically ill patients from January 2021 to January 2023 in the Intensive Care Unit,Quanzhou First Hospital Affiliated to Fujian Medical University were selected and divided into control group and observation group,with 75 cases in each group.The control group patients were treated with conventional rehabilitation measures combined with the boot-type intermittent pneumatic compression therapy device for intermittent inflation and compression therapy,while the observation group patients received the bioinformatic feedback infrared therapy besides the treatment in control group.The incidence of DVT,the average time for swelling and pain reduction,the average time for swelling and pain disappearance,total hospitalization time,the hemodynamic indexes of the lower extremities,coagulation indexes,D-dimer,the recurrence rate of swelling and pain,satisfaction with the rehabilitation,and therapeutic efficacy were recorded.Results After 3 months of discharge,the rate of post-discharge swelling and pain recurrence in observation group was 2.67％(2/75),obviously lower than 10.66％(8/75)in control group(P＜0.05).After 14 days of intervention,the lower extremity deep vein blood flow velocity and peak blood velocity of the two groups increased significantly as compared with those before intervention(P＜0.05),and those were greater in observation group than in control group(P＜0.05).After 14 days of intervention,the coagulation indexes(PT,TT,FIB)and D-dimer level were significantly lower or shorter in both groups as compared with those before intervention(P＜0.05);and observation group had shorter PT and TT,and lower levels of FIB and D-dimer than control group(P＜0.05).The average time for swelling and pain reduction,the average time for swelling and pain disappearance,and the total hospitalization time were shorter and the incidence of DVT was obviously lower in observation group as compared with control group(P＜0.05).The overall response rates of 14-day intervention in observation group vs control group were 97.33％(73/75)vs 88.00％(66/75)(P＜0.05).At the discharge,the satisfaction rates in observation group vs control group were 96.00％vs 85.34％(P＜0.05).Conclusion The combination of bioinformatic feedback infrared therapy and boot-type intermittent pneumatic compression therapy device for intermittent inflation and compression therapy can shorten the average time for swelling and pain reduction,the average time for swelling and pain disappearance and the total hospitalization time,enhance the hemodynamics of the lower extremities,improve the coagulation function and D-dimer level,and improve the satisfaction with the rehabilitation and clinical efficacy,worthy of clinical promotion.

Objective: To evaluate measurement acquisition, operability, and measurement agreement of the OA-2000 in cataract eyes with high myopia. Methods: A diagnosis test examined 1 030 eyes of 780 high-myopia cataract patients at the Wuhan Aier Eye Hospital from October 2017 to October 2018.The eyes were examined using the OA-2000, the IOLMaster 500 and the Lenstar-LS900 preoperatively.Measurement acquisition was recorded.The total ophthalmic exam, the duration of patient data entry, the actual measurement process, and the time from intraocular lens power calculation to printout were calculated.Ocular biometric parameters, including anterior chamber depth (ACD), axial length (AL), keratometry for the flattest meridian (Kf), and keratometry for the steepest meridian (Ks) were compared among the devices.This study complied with the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Wuhan Aier Eye Hospital (No.2017IRBKY07). Results: The OA-2000 was capable of obtaining an AL measurement in 94.95% of the eyes, which was significantly higher than the 83.98% and 83.01% measured by the IOLMaster 500 and Lenstar-LS900, respectively (χ²=38.171, 46.208; both at P<0.001). The total ophthalmic exam with the OA-2000 took a significantly shorter time than the Lenstar-LS900 ([109.34±2.22]s vs. [135.64±5.55]s) (P<0.05). Excellent correlations were found for the AL, ACD, Kf, and Ks measurements between the OA-2000 and the IOLMaster 500 (r=0.999, 0.937, 0.996, 0.996; all at P<0.001). Good correlations were also found between the OA-2000 and the Lenstar-LS900 (r=0.999, 0.965, 0.995, 0.996; all at P<0.001). The respective 95% limits of agreement of the OA-2000 and IOLMaster 500, and the OA-2000 and Lenstar-LS900 were -0.19 to 0.20 mm and -0.13 to 0.17 mm for AL; -0.23 to 0.23 mm and -0.18 to 0.16 mm for ACD; -0.48 to 0.47 D and -0.64 to 0.65 D for Kf; -0.49 to 0.47 D and -0.60 to 0.61 D for Ks. Conclusions In terms of AL, ACD, Kf and Ks in cataractous eyes with high myopia, the OA-2000, IOLMaster 500, and Lenstar-LS900 show excellent correlation and agreement.The OA-2000, a new swept-source OCT-based biometer, outperforms both the IOLMaster 500 and the Lenstar-LS900 in terms of AL measurement acquisition and operability.