Objective To evaluate the significance of serum prealbumin, bilirubin/albumin( B/A )ratio and brainstem auditory evoked potential (BAEP)for early predicting the bilirubinic neurotoxicity caused by early neonatal hyperbilirubinemia. Methods According to the gestational age, birth weight and the intervention criterion of neonatal jaundice, 94 neonates (newborn infants with a age of 1-7days) with hyperbilirubinemia were divided into two groups, one was term neonates with normal BAEP, the other was term neonates with abnormal BAEP. We detected their serum levels of total bilirubine, prealbumin, BAEP and calculated B/A ratio. Result The prealbumin levels was significantly lower and B/A ratio was higher in group of abnormal BAEP than those of control group ( P < 0. 01 ), while the levels of total bilirubin were not significantly different between the two groups ( P > 0. 05 ). In group of abnormal BAEP , there was a negative correlation between the level of serum prealbumin and the B/A ratio (r = -0. 637, P <0. 01 ). Conclution Prealbumin may be a sensitive indicator for early predicting bilirubinic toxicity like B/A ratio and BAEP.

Pancreatic resection is the treatment choice for pancreatic malignancy and cer-tain benign pancreatic disorders. Althogh, pancreatic resection requires high techndogy whereas current mortality after a pancreaticoduodenectomy has dropped to below 3 % in expe-rienced high-volume centers and post-operative morbidity is still as high as 50%. At pres-ent, the single most significant cause of morbidity and mortality after pancreatectomy is the development of pancreatic leakage and fistula (PF). The occurrence of a PF increases the length of hospital stay and the cost of treatment, requires additional investigations and proce-dures, and can result in life-threatening complications. Early recognition of a PF and prompt institution of appropriate treatment is critical to the prevention of potentially devastating con-sequences; however there is no universally accepted definition of PF that would allow stand-ardized reporting and proper comparison of outcomes between different centers. The present article reviews the conlept evolution of PF and discusses the current preventive strategies.

Objective To study the curative effect of gearing lumbar disc herniation with intecverthral disc version operation. Methods 220 patients were randomly recruited into a treatment group (with 120 patients) and a control group (with 100 patients). The treatment group was treated with intervertbral disc version operation, and the control group was treated with epidural injection combined with massage therapy. Evaluate the therapeutic effects at 1 week, three months, and one year after the treatment respectively. Results The therapeutic effect of at 1 week, three months, and one year after the treatment was 83.46%, 86.19%, 93.45% respectively in the treatment group, and 64.68%, 69.08%, 71.04% respectively in the control group. The difference between the two groups was significance. (P<0.05). Conclusion Intervertbral disc version operation was safe and effective in treating lumbar disc herniation.

Objective To investigate the curative effect for lumbar spondylolisthesis by posterior lumbar intervertebral compression bone graft fusion and pedicle screw internal fixation.Method All 39 cases with lumbar spondylolisthesis accepted treatment during January 2003 to October 2007.There were cataplasia spondylolisthesis in 14 cases and isthmic spondylolisthesis in 25 cases.Twenty-two cases had spondylolisthesis in L4 and 17 cases had spondylolisthesis in L5.According to Meyerding grading,11 patients were classified as degree Ⅰ lesion.27 patients as degree Ⅱ lesion and 1 patient as degree Ⅲ lesion.By the help of X-ray machine,pedicle screw Was embedded in the vertebral spondylolisthesis and it Was lower vertebra.Laminectomy decompress was administered in vertebral spondylolisthesis and hold-down bars was placed to open intervertebral space.Then restored the vertebral spondylolisthesis and fixed it temporary.Next,intervertebral compression bone graft fusion was finished and was adjusted.Results Follow-up period was 5 months to 4 years.Clinical outcomes were measured with Prolo evaluation scale,35 cases were cured,4 cases were good effect.Conclusions This operation has been found to be asafe,rapid and effective method for lumbar spondylolisthesis and it produces a high fusion rate and lower expense.

Poly(ethylene glycol)(PEG) coated silver nanowires has been hydrothermally prepared at a very slow rate, in which PEG was used as both a mild capping agent and a weak reductant. As-prepared silver nanowires(SNWs) have been characterized using scanning electron microscopy) and transmission electron microscope), which showed that the SNWs are usually longer than 100 μm and their diameters(each SNW has a uniform thickness) vary mainly in the range of 80～300 nm. Surprisingly, some of these silver nanowires connected) by their two ends to form some close-looped silver nanowires, which hitherto has not been reported elsewhere. The existence of close-looped silver nanowires supports the mechanism that nanowires can evolve from fusion of some nanoparticles and/or shorter nanorods. Careful TEM characterization and selected area electron) diffraction revealed that the silver nanowires kept a five-fold twinned structure, which is opposite to some reports) that a long-time incubation will lead to the disappearance of this twin structure. This work demonstrates the situation that deeper investigation is still needed for understanding the structure transformation of silver) nanowires.

Three-dimensional (3D) reconstruction of medical images constructs the 3D models of organs using 2D medical image serials, which provide intuitionistic visual information for medical workers. However, most people concern about the CT images reconstruction, only few people focus on the reconstruction of Ultrasound images. In this thesis, it introduces Insight Segmentation and Registration Toolkit (ITK) and The Visualization Toolkit (VTK) firstly. Then it presents the process of Ultrasound image serials using ITK and VTK. At last, it presents the outcome of the experiment. The results show that the reconstruction of Ultrasound images can also get good effect by using ITK and VTK.

Objective　To investigate the causes and preventive methods of postoperative complications of femoral shaft fracture treated with intramedullary interlocking nails. 　Methods　A total of 116 patients with femoral shaft fractures admitted to our hospital from 1994 to 1999 were retrospectively studied in this article. They were all treated with intramedullary interlocking nails. The locking nails were removed from the 14 patients with delayed union to convert the fixation from static to dynamic. For the 6 patients with bone nonunion, the locking nails were removed, and new locking nails and bone grafts were employed. And for the 4 patients with bone infection, the foci were cleaned and the locking nails were removed, then certain external fixation was applied.　Results　Followed up for 1 year, the fractures of 14 patients with delayed union were completely healed. For the 6 patients with bone nonunion, reoperation was needed in 4 patients and a third operation needed in 2 patients, and they all healed after being followed up for one and half a year. For the 4 patients with bone infection, only 3 patients healed. The whole effective rate was 95.8%. 　Conclusions　Although the intramedullary interlocking nails used for femoral shaft fractures have advantages than other internal fixations, the complications of delayed healing, nonunion, bone infection and breaking nails are often found. The effective measures to reduce the complications include strict master of the operative indications, suitable materials for the implant and conversion of the fixation from static to dynamic in time, careful selection of debriding the realm or debriding no realm, complete debridement and strict abacterial procedures.

NF-κB is a nuclear transcription factor with multiple adjustion. The activation of NF-κB can occur by three different mechanisms. The multiple NF-κB activation pathways are important due to the large number of genes that are regulated by NF-κB and their effects on cancer cells. These gene products can promote growth and tumori-genesis, inhibit apoptosis, allow metastasis and invasion, promote angingenesis, and cause chemoresistance. All of these roles in pancreatic cancer make NF-κB a promising target in treatment. Therefore, inhibiting the activity of NF-κB becomes a hot spot and novel idea of preventing and treating pancreatic cancer.

Studies have shown that the compliance of secondary prevention of ischemic stroke is not ideal. Among the factors that impact the compliance of secondary prevention, the correlation of the gender, age or disease severity has no clear conclusion. However, the married, the higher proportion of medical reimbursement, a better understanding of the disease, early intervention, the doctor's degree of attention, and a good doctor-patient relationship may improve the compliance of secondary prevention of ischemic stroke.

Objective To observe the clinical therapeutic effects of Yishen-Jianpi-Huoxue Decoction on the adolescent patients with Polycystic Ovary Syndrome (PCOS).Methods 42 patients diagnosed of PCOS of spleen and kidney deficiency syndrome were recruited in to traditional Chinese medicine group and treated with Yishen-Jianpi-Huoxue Decoction,and 35 patients of PCOS were recruited into control group and guided with the healthy lifestyle.The course of the treatment was 3 months.The menstrual cycle,body mass index (BMI),F-G score,GAGS score,basal body temperature (BBT),and endocrine related inspection were analyzed before and after the treatment.Results The clinical symptoms and related laboratory tests were improved in both groups after the treatment,but the effects of traditional Chinese medicine group was much better than the control group in BMI(23.11+3.64),GAGS score(7.33±7.06),FINS(14.73+8.97) mmol/L,and HOMA-IR (3.13 ±1.94),P＜0.05 or ＜0.01.Conclusion Yishen-Jianpi-Huoxue Decoction can improve the clinical symptoms and endocrine condition of edolescent PCOS patients.