Purpose: assessing the effectiveness of ELISA using sonicated antigen of M. tuberculosis in the diagnosis of adult infiltrative pulmonary tuberculosis. Materials: 102 patients from 18 to 70 years old were diagnosed as preliminary infiltrative tuberculosis by clinic and X-ray. And then, 58 patients of them with infiltrative tuberculosis according to the criteria of WHO (1997) and Chebanov V-1980, the rest(control) with lung disease non tuberculosis (4 pneumonie, 6 abcess, 34 lung tumors). Methods: serum of 102 patients were ELISA tested for IgG antibody against sonicated antigen of M. tuberculosis OD= 0,5 was a cut off value for IgG measurements (Charpin D. 1995). Chest-X-ray-images were analyzed by Pr. Bui Xuan Tam and Dr. Hoang Van Huan. Results: 1. The mean IgG value in the infiltrative tuberculosis group was significantly higher than non-tuberculosis group (p<0.001) (0.863+/-0.395 vs 0.252+/-0.19). 2. The larger new tuberculosis lessions on chest-X-ray, the stronger humoral immuno response (P< 0.01), that did not related to Mantoux test. 3. Test ELISA using sonicated antigen of M. tuberculosis, having the sensitivity 81.03%, the specificity 95.45%, the posititive predictive value 95.91%, the negative predictive value 79.24%, the accuracy 87.25%. Conclusion: ELISA can be an useful test for the rapid diagnosis of infiltrative pulmonary tuberculosis.
Tuberculosis, Pulmonary ; Enzyme-Linked Immunosorbent Assay

40 patients from 18 to 64 years old (32 males, 8 females) with pulmonary tuberculosis according to the WHO criteria 1977 were subjected to study on effectiveness of thoracic CT in diagnosis for post primary pulmonary tuberculosis, among them 8 were treated surgically. CT scanner images were analyzed and compared with standard chest radiography (SCR). Results show the advantage of CT scanner in comparison with SCR for detecting basic lesions, their location and their extension; also detects other associated lesions such as bronchiectasis and sequelae of tuberculosis (pleural thickening) and other tuberculosis lesions (fibrosis lesions, tuberculoma, infiltrated without cavity) which can be mistaken with lung tumors (mistaken rate 20%).
Tuberculosis, Pulmonary ; Tomography Scanners, X-Ray Computed ; Adult ; Diagnosis