1.The interventional treatment for hepatocellular carcinoma originating from the caudate lobe
Journal of Clinical Hepatology 2016;32(1):68-71
Hepatocellular carcinoma (HCC)originating from the caudate lobe is a special-site HCC,which is rare and difficult to treat. The major therapeutic method in the past was surgical resection.In recent years,interventional treatment for HCC originating from the cau-date lobe has achieved significant progress,and good therapeutic effect has been obtained.This paper briefly introduces the anatomic fea-tures of the caudate lobe and the features of blood supply in HCC originating from the caudate lobe,reviews the research advances in the therapeutic methods of transcatheter arterial chemoembolization and local ablation for HCC originating from the caudate lobe,and points out that a combination of interventional therapies for HCC originating from the caudate lobe needs to be further investigated in clinical practice.
2.Improved simulate annealing algorithm for therapy planning optimization in intensity modulated radiation therapy
Lei GAO ; Junhua ZHANG ; Huaming WANG
Chinese Medical Equipment Journal 2004;0(08):-
It is the key to search the best intensity distribution of pen beam in intensity modulated radiation therapy.The traditional method is based on simulation of annealing algorithm.In this paper,we use an improved method,which shows good performance in both the quality and efficiency.
3.Children’s old Monteggia fracture:Annular ligament reconstruction or not?
Huaming WANG ; Zhilong CHEN ; Weiping LI
Chinese Journal of Tissue Engineering Research 2013;(35):6357-6363
BACKGROUND:Radial head re-dislocation is one of the alarming complications of old Monteggia fracture. Many treatment methods have described the necessary of fracture and annual ligament reconstruction during treatment, but stil unclear.
OBJECTIVE:To emphasize the practicality of annular ligament reconstruction through comparing the children’s treatment in two groups.
METHODS:Twelve patients with children’s old Monteggia fracture were included for retrospective analysis. Al the patients were treated with radial head open reduction and internal fixation. Among them, five cases received ulna extending osteotomy and annual ligament reconstruction, and seven cases received ulna extending
osteotomy without annual ligament reconstruction. The course was 3-18 months from damage to the clinical
manifestations (an average of 9 months). Ten cases with Bado type Ⅰ and two cases were Bado type Ⅱ andⅢ. The reliability of ligament reconstruction was evaluated before and after treatment with Kim standard.
RESULTS AND CONCLUSION:Al the 12 cases were fol owed-up for 22 months (8-26 months). Evaluation
according to the Kim standard after treatment showed excel ent in 10 cases without abnormalities and pain, the range of motion>250 °, and no elbow was limited, the activities of daily living was 25 points;good in two cases with mild deformity and mild or intermittent pain, the range of motion was 200°-250° with elbow limited, activities of daily living was 15 points;no poor (serious deformity, pain, range of motion<200°, elbow severely limited, activities of daily living was 0 points). Fol owed-up lasted for 22 months and found that the average healing time of ulnar
osteotomy was 8 weeks (6-14 weeks). The wounds were healed primarily without infection and nonunion. The
results indicate that ulna extending osteotomy has great significance in keeping stability of radial head, and annular ligament reconstruction is determined by the time of injury, surgical procedures and intraoperative radial head stability.
4.The Path Selection of Achieving Health Justice in New Period: Primary Health Care
Xiaohe WANG ; Qing GUO ; Huaming HE
Chinese Medical Ethics 1995;0(02):-
From the view of realizing health justice,The paper discusses the consistent objective between health justice and "Primary Health Care for all".It put forward and expound that PHC is the effective path of realizing health justice in new period,and some proposal which strengthen government's responsibity and function about PHC,as well as develop the health service in community both in urban and rural areas,with the focus on PHC in rural areas.
5.A study of botulinum atoxin and uitrashort wave treatment of trigeminal neuralgia
Yongkang YUAN ; Jie WANG ; Huaming WANG ; Jun ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2015;(19):2898-2901
Objective To investigate clinical efficacy about treatment of trigeminal neuralgia using botulinum toxin of type A and ultrashort wave.Methods 40 patients with trigeminal neuralgia were randomly divided into the control group(n =20)and the treatment group(n =20)according to digital table method,patients in the control group were injected with lidocaine,triamcinolone acetonide and vitamins B12 injection in pain -sensitive point,the treatment group were injected botulinum toxin of type A 50 -150 u in pain -sensitive point.The two groups were in the ultrashort wave therapy.Used VAS pain scores to evaluate local pain about two groups of patients before treatment,one week after treatment,one month after treatment,three months after treatment,the clinical efficacy after treatment at different time points were compared between the two groups.The two groups of patients showed sleep improvement,the sleep status of patients were observed.Results The VAS score in the control group 1 week after treatment was (3.78 ± 1.35)poinrs,and was (7.03 ±1.07)poinrs before treatment,the difference was statistically significant(t =-3.39, P <0.05);The VAS scores at 1 month and 3 months after treatment were respectively (6.32 ±1.08)poinrs and (7.45 ±1.03)poinrs,the data had no statistical significance as compared with that before treatment (P >0.05). After treatment for 1 week,the scores of VAS in the treatment group was (5.18 ±1.03)poinrs,which was decreased compared with that before[(7.63 ±1.04)poinrs],the difference was statistically significant(t =4.23,P <0.05). After treatment for 1 month and 3 months,the VAS scores were respectively (4.01 ±1.78)poinrs and (2.95 ± 1.34)poinrs,significantly lower than that before treatment,the differences were statistically significant(t =4.97, 5.34,all P <0.05).After treatment for 1 week,differences of VAS scores in the two groups showed no statistical significance(P >0.05).After the treatment for 1 month and 3 months,VAS score differences were statistically signifi-cant(t =7.56,11.61,all P <0.05).In the control group,after treatment for 1 week,1 month and 3 months showed significant efficiency of 77.5%,33.3% and 11.1% respectively,which showed a downward trend.In the treatment group,after treatment for 1 week,1 month and 3 months,the efficiency were 57.7%,69.2% and 80.7%,which was a rising trend.And the efficiency was significantly higher than that of the control group,the differences were statistically significant(χ2 =5.16,17.99,P <0.05).Conclusion The treatment of trigeminal neuralgia using botulinum toxin of type A with ultrashort wave can significantly reduce pain in patients,the effect is better than lidocaine,triamcinolone acetonide and vitamin B12 .
6.Effect of Local Insulin Injection on Crushed Injury of Facial Nerve in Rats
Yuhua ZHANG ; Huaming WANG ; Jie YIN ; Yuhong JING
Chinese Journal of Rehabilitation Theory and Practice 2014;(9):839-841
Objective To investigate the effect of local insulin injection on neurological function after crushed injury of facial nerve in rats. Methods Facial nerve was crushing injured in 30 Sprague-Dawley rats, from which 20 selected rats were divided into treatment group (n=10) and control group (n=10). The treatment group was injected with insulin 250 ng/kg at innervated muscle, and the control group was injected with normal saline. They were assessed with neurologic deficit score everyday within 7 days after injection, and the regeneration of nerve fiber was observed with retrograde fluorogold labeling. Results Compared with that in the control group, the neurological deficit score was improved more 5~7 days after injection in the treatment group, and the count of fluorogold labeling cells increased more in the treatment group. Conclusion Local injection of insulin can promote the recovery of neurological function after crushed injury of facial nerve.
7.Elastic intramedullary nail for the treatment of femoral shaft fracture in children with failed plate fixation
Huaming WANG ; Zhilong CHEN ; Weiping LI ; Shengtai PEI ; Shihai CHEN
Chinese Journal of Tissue Engineering Research 2013;(26):4819-4825
10.3969/j.issn.2095-4344.2013.26.010
8.EFFECTS OF CROCODILE BONE GELATIN ON STRESS REACTION AND BLOOD-FORMING FUNCTION IN MICE
Hui LI ; Fang PENG ; Huaming ZHANG ; Chengjun WANG
Chinese Journal of Marine Drugs 2000;0(06):-
To investigate the effects of Crocodile Bone Gelatin(CBG) on stress reaction and blood forming function in mice. Results showed CBG increased staying power for high temperature and low temperature, but didn′t increase anti exhaustion ability and hypoxia tolerance of mice. CBG increased platelet count, didn′t increase white blood cell count on Cyclophosphamidum causing blood forming functional obstruction.
9.Diagnosis and Interventional Therapy by Spiral CT in Rupture of Hepatocellular Carcinoma
Jinghui DONG ; Huaming WANG ; Junhua ZHANG ; Yongwu LI ; Wei MA
Journal of Medical Research 2006;0(01):-
Objective To investigate the diagnosis and the curative effects of interventional therapy by spiral CT in rupture of hepatocellular carcinoma(HCC). Methods 46 patients were checked by spiral CT and abdominal puncture of non-condensable blood. All the patients were treated by the transcatheter arterial embolization (TAE) with iodinated oil and/or gelatin sponge. Results Characteristic findings were detected in 31 patients,of which 7 patients were chiefly detected by spiral CT. The bleeding of ruptured HCCs was controlled effectively in all the cases treated by TAE without serious complications. Conclusion Spiral CT is susceptive to the diagnosis of the ruptured HCC. TAE can be the chiefly treatment in ruptured HCC with fewer serious complications.
10.Laparoscopic surgical treatment for schistosomiasis liver fibrosis portal hy-pertension combined with calculous cholecystitis
Lan ZHANG ; Xiong LIU ; Huaming ZHANG ; Qingshan WANG
Chinese Journal of Schistosomiasis Control 2014;(2):230-231,233
Objective To evaluate the curative effect of laparoscopic cholecystectomy(LC)in the treatment of schistosomia-sis liver fibrosis portal hypertension combined with calculous cholecystitis. Methods The clinical data of 196 cases of schistoso-miasis liver fibrosis portal hypertension combined with calculous cholecystitis(Child A 160 cases,Child B 36 cases)treated with LC were collected and analyzed from June 2006 to June 2013. Results Among the 196 cases,there were 154 cases of schistoso-miasis liver fibrosis portal hypertension combined with chronic calculous cholecystitis,and 42 cases of schistosomiasis liver fibro-sis portal hypertension combined with acute calculous cholecystitis. Totally 189 patients underwent LC successfully,but 7 were transited to the general operation because of LC failure,including 3 cases of adhesion around gallbladder and ambiguous dissec-tion of gallbladder triangle,and 4 cases of intraoperative bleeding and the bleeding was difficult to stop under the laparoscopy. All the 196 patients were cured. Conclusion LC is effective and safe in the treatment of schistosomiasis liver fibrosis portal hyperten-sion combined with calculous cholecystitis.