The arteries of the breasts of 25 Chinese female cadavers, injected with color latex, were dissected and observed by surgical microscope. These arteries originate from the first, second and third perforating branches of the internal thoracic artery. They were classified into five types. The two branch type occured most frequently (54%), and is musculoadenocutaneous in nature. The distribution of this type of artery is in four directions, one branch to the nipple, the second branch to the axilla, the third branch to the sternum and the last branch to the clavicle. The second perforating branch is the largest in diameter, 0.92 mm., the first and third perforating branches come next. The area of distribution of the second perforating branch is also the largest, 6265.50 mm2, and the third and first perforating branches come next. The first perforating branch crosses the 4 th rib in 52%, and that of the second perforating branch in 43%. The arteries supplying the medial portion of the breast have an extensive anastomoses (48%) with those arteries of the lateral portion.

The arterial blood supply of the lateral portion of the breasts was studied in 50 sides of 25 Chinese female cadavers. The results are obtained as follows: 1.the arteries leading to the lateral portion of the breast are constant. Among them, 38% originates from the lateral thoracic artery, 24% from the brachial artery and 15% from the axillary artery. 2.One branch type arteries were found in 28 breasts (56%),two branch type arteries in 20 breasts (40%) and three branch type arteries in 2 breasts (4%). 3.The average diameter of the arterial origin isl.37.06mm.the average length of the artery is 171.9?5.82 mm. and the average range of distribution is 52.8?6.18 mm. 4.Besides supplying the skin of the lateral portion of the breast, the artery also supplies the gland, areola and the nipple. 5.The branches arising from the axillary artery arc musculoadenocutaneous, and those arising from the brachial artery are adenocutaneous. 6.The average distance between the artery and the center of the nipple is 38.6?4.34 mm. 7.The arterial supply is rich in anastomoses with its surrounding arteries, especially with the papillary branches of the internal thoracic artery. 8.The arteries originating from the brachial artery have long pedicles and their location is superficial and constant. Lastly, clinical significance of these arteries were discussed.

Objective To explore the diagnostic value of the quantitative detection of miRNA-145 and miRNA-143 in the ser-um of children with Kawasaki disease (KD).Methods In this study,45 KD cases were enrolled and were divided into 19 ca-ses with coronary artery lesions (CAL group)and 26 cases without coronary artery lesions (NCAL group).Thirty healthy children were recruited as the control group (NC group).qRT-PCR was conducted to detect the expression of miRNA-145 and miRNA-143 in serum of each group.The diagnostic value of miRNA-145 and miRNA-143 were evaluated by receiver op-erating characteristic curves (ROC)and the area under the curve (AUC)(95%CI).Results The relative expressions of miRNA-145 and miRNA-143 in the serum of the CAL group in acute phase were 2.33±1.26 and 1.64±0.50,which were respectively higher than the control group,with statistically significant difference (t=5.108,5.072,P<0.01).The relative expression of miRNA-145 during the recovery phase of CAL group was 1.55±0.49,which was statistically significant high-er than NC group (t=3.837,P<0.01).While the relative expression of miRNA-143 during the recovery phase of CAL group was 1.17±0.33 and had no difference with NC group (t=1.033,P>0.05).During the acute phase of NCAL group, the relative expressions of miRNA-145 and miRNA-143 were 2.02±1.00 and 1.63±0.50 respectively.They were signifi-cantly higher than the control group (t=4.746,5.261,P<0.01).However,when comes to the recovery phase,the relative expression of miRNA-145 and miRNA-143 were 1.07±0.18 and 1.12±0.16,which had no difference with NC group (t=0.264 9,0.584 9,P>0.05).The critical value of miRNA-145 for diagnosis of KD was 1.697 with sensitivity of 64.44% and specificity of 90% and yielded an area under the curve of ROC of 0.7733 (95%CI:0.667 0~0.879 7).Also,the critical val-ue of miRNA-143 was 1.361 with sensitivity of 64.44% and specificity of 86.67% and yielded an area under the curve of ROC of 0.8163 (95%CI:0.722 5~0.910 0)in discriminating KD from healthy group.Conclusion miRNA-145 and miR-NA-143 may prove to be a non-invasive biomarker for the auxiliary diagnosis of KD.

Objective To explore the diagnostic value of the quantitative detection of plasma miRNA-125b and miRNA-133b in children with asthma.Methods Thirty asthmatic patients were enrolled in this study and collected the blood specimens during acute phase and stable phase respectively (AP group and SP group).Thirty allergic rhinitis children (AR group) and thirty healthy children were recruited to the control group (NC group).The levels of miRNA in different groups were detected by qRT-PCR.The performance of miRNA-125b and miRNA-133b were evaluated by receiver operating characteristic curves (ROC) and the area under the curve (AUC) (95％CI).Results The relative expression of miRNA-125b in AP group and SP group were significantly higher than A R group (t=3.913,3.120,P＜0.01),miRNA-133b.In AP group and AR group the expression of miRNA-133b were significantly higher than control group (t=4.426,4.720,P＜0.01).The detection of miRNA-125b yielded an area under the curve of ROC of 0.7989,(95 ％ CI:0.7111～ 0.8864) in discriminating asthmatic patients from healthy group.And the miRNA-133b was 0.7274 (95％CI:0.586 5～0.863 0) in discriminating asthmatic patients during the acute phase from healthy group.Conclusion The relative expression of miRNA-125b in children with asthma was significantly higher than that in AR group and NC group,miRNA-125b may prove to be a non-invasive biomarker for the auxiliary diagnosis of asthma especially when the relative expression up to 1.998.