1.Correlation between macrophage inflammation protein-1α as well as tumor necrosis factor-α in gingival sulcus fluid and the condition of chronic periodontitis and its therapeutic efficacy
Journal of Clinical Medicine in Practice 2017;21(17):42-44
Objective To explore the relationship between macrophage inflammation protein-1 α(MIP-1 α) as well as tumor necrosis factor-α(TNF-α) in gingival sulcus fluid and chronic periodontitis and its curative efficacy.Methods A total of 52 chronic periodontitis patients in our hospital were selected as experimental group and 30 healthy subjects were selected as control group.The experimental group received basic periodontal treatment (supragingival scaling and subgingival curettage) and oralhealth education while the control group was only given GI,BI,PG,AL examination without any treatment.The correlation between contents of MIP-1α as well as TNF-α in gingival sulcus fluid before and after treatment in two groups and the gingival indicators (GI),bleeding index (BI),and the depth of the probe (PD) were explored.Results Before treatment,the GI,BI and other clinical indicators of experimental group were higher than that in the control group (P < 0.05).The GI,BI and other clinical indicators of effective patients in the experimental group were lower than that of the control group after treatment (P < 0.05).MIP-1 α as well as TNF-α in gingival sulcus fluid were significantly correlated with clinical indicators (P < 0.05).After treatment,the content of MIP-1 α as well as TNF-α in gingival crevicular fluid in the experimental group were lower than treatment before (P < 0.05).Conclusion MIP-1 α as well as TNF-α in gingival crevicular fluid are correlated with periodontal clinical indicators.
2.Correlation between macrophage inflammation protein-1α as well as tumor necrosis factor-α in gingival sulcus fluid and the condition of chronic periodontitis and its therapeutic efficacy
Journal of Clinical Medicine in Practice 2017;21(17):42-44
Objective To explore the relationship between macrophage inflammation protein-1 α(MIP-1 α) as well as tumor necrosis factor-α(TNF-α) in gingival sulcus fluid and chronic periodontitis and its curative efficacy.Methods A total of 52 chronic periodontitis patients in our hospital were selected as experimental group and 30 healthy subjects were selected as control group.The experimental group received basic periodontal treatment (supragingival scaling and subgingival curettage) and oralhealth education while the control group was only given GI,BI,PG,AL examination without any treatment.The correlation between contents of MIP-1α as well as TNF-α in gingival sulcus fluid before and after treatment in two groups and the gingival indicators (GI),bleeding index (BI),and the depth of the probe (PD) were explored.Results Before treatment,the GI,BI and other clinical indicators of experimental group were higher than that in the control group (P < 0.05).The GI,BI and other clinical indicators of effective patients in the experimental group were lower than that of the control group after treatment (P < 0.05).MIP-1 α as well as TNF-α in gingival sulcus fluid were significantly correlated with clinical indicators (P < 0.05).After treatment,the content of MIP-1 α as well as TNF-α in gingival crevicular fluid in the experimental group were lower than treatment before (P < 0.05).Conclusion MIP-1 α as well as TNF-α in gingival crevicular fluid are correlated with periodontal clinical indicators.
3.Study of the Er: YAG laser in periodontal flap surgery for the treatment of chronic periodontitis
LIU Zhenzhe ; ZHAO Liang ; HUANG Huairong ; HUANG Wenxia ; CHEN Hongbai
Journal of Prevention and Treatment for Stomatological Diseases 2018;26(9):574-577
Objective:
Objective To explore the role of the Er: YAG laser in periodontal surgery.
Methods :
Twenty patients with chronic periodontitis in two quadrants were selected for this study. One quadrant was subjected to pure periodontal flap surgery, whereas the other was subjected to flap surgery with an adjunctive Er: YAG laser. The preoperative and 3- and 6-month postoperative clinical parameters, including the probing depth, clinical attachment level, gingival recession, plaque index, gingival index and tooth mobility, were recorded.
Results:
Significant differences were not observed between the open flap surgery + Er: YAG laser-assisted treatment group and the open flap surgery group except for the gingival index after 3 months (0.36 ± 0.26 vs. 0.58 ± 0.29, t=3.831, P < 0.001) and 6 months (0.60 ± 0.23 vs. 0.83 ± 0.22, t=4.013, P < 0.001).
Conclusion
Er:YAG as an auxiliary treatment for periodontal flaps, does not significantly reduce the depth of periodontal pockets, nor could it improve the clinical adhesion level and the gingival recession, but it can improve the recovery of gingival inflammation and accelerate the healing of tissue.