Scars caused by trauma will not only affect the appearance and cause dysfunction, but also affect the quality of psychological life of the patients to varying degrees. With the in-depth understanding of the process of scar formation after trauma and the continuous development of related intervention methods, early intervention within 3 months after trauma has been proved to be able to promote wound healing, inhibit scar hyperplasia, and interfere with the natural remodeling of scar collagen. This review summarizes the process of scar formation after trauma, as well as the timing and method of early intervention.

OBJECTIVETo compare the ettect and side-ettect of fluoxetine and combination of fluoxetine and Chinese or Tibetan medicine in treating senile depression in plateau district. Methods Ninety patients with diagnosis of senile depression conformed to CCMD-3 standard, in plateau district of 2260 - 3200 m altitude were randomly divided into three groups and treated with fluoxetine (group A), fluoxetine plus Sanpu Xinnao Xin granule (group B) and fluoxetine plus Xiaoyao pill (group C), respectively, 30 cases in each group. Therapeutic effects were evaluated with Hamilton' s depressive scale (HAMD) and treatment emergent symptom scale (TESS) after 6 weeks treatment.

RESULTSThere was no significant difference in the therapeutic effects between the three groups. The adverse reaction in Group B and C was less than that in Group A (P<0.01). Conclusion Sanpu Xinnao Xin granule and Xiaoyao pill can raise the tolerance of patients with senile depression in plateau area against the adverse reaction of fluoxetine.

Aged ; Altitude ; Antidepressive Agents, Second-Generation ; therapeutic use ; Depressive Disorder ; drug therapy ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Fluoxetine ; therapeutic use ; Humans ; Middle Aged ; Phytotherapy ; Serotonin Uptake Inhibitors ; therapeutic use

The patient, a 19-year-old female, found that the blue and purple mass was in her left forearm 3 years ago, and the mass gradually increased without obvious pain. It disappeared when pressing. The first diagnosis was "left forearm venous malformation" . During the operation, the boundary of the tumor body was clear and the capsule was complete. The blood supply of the tumor body was very rich. There were many micro capillary networks in the tumor body. It looked like "venous malformation" by general observation. But it was diagnosed as subcutaneous hamartoma by pathological examination. It was very similar to venous malformations by preoperative and intraoperative clinical manifestations, which will lead to misdiagnosis. Therefore, we should carefully handle and broaden the thinking of disease analysis in the similar cases.

The patient, a 19-year-old female, found that the blue and purple mass was in her left forearm 3 years ago, and the mass gradually increased without obvious pain. It disappeared when pressing. The first diagnosis was "left forearm venous malformation" . During the operation, the boundary of the tumor body was clear and the capsule was complete. The blood supply of the tumor body was very rich. There were many micro capillary networks in the tumor body. It looked like "venous malformation" by general observation. But it was diagnosed as subcutaneous hamartoma by pathological examination. It was very similar to venous malformations by preoperative and intraoperative clinical manifestations, which will lead to misdiagnosis. Therefore, we should carefully handle and broaden the thinking of disease analysis in the similar cases.