Objective To compare the effect of total hip replacement and artificial femoral head replacement in treat-ment of femoral neck fractures in senile patients. Methods All 100 patients were selected as the research object in our hospital from 2009 June to 2014 June, all aged over 60 years old, signed the informed consent. The patients were di-vided into A group and B group,with 50 cases in each group,group A underwent total hip arthroplasty,group B under-went artificial femoral head replacement. Results All the patients were follow-up for 1 years,the follow-up rate A was 100%. The excellent rate of hip joint function after operation in group A was 84%, the excellent rate in B group was 62%,there were significant differences (χ2=6.329,P<0.05). Display the postoperative follow-up of 3, 6 months, the Harris score in group A after 6 months compared with after surgery 3 months significantly increased, and the Harris score in group A after 3 months,6 months were higher than that of group B,there were significant differences(P<0.05). Operation time of A group were significantly longer than those of group B,the amount of bleeding,postoperative group A after drainage were significantly more than that in group B, the difference was significant(P<0.05). The incidence of complications of group A and B, with no significant difference (P>0.05). Conclusion Total hip arthroplasty and hemiarthroplasty was one of effective methods to treat femoral neck fractures in the elderly, the advantages and disad-vantages of each, the treatment of senile femoral neck according to the specific circumstances of patients timely, rea-sonable selection of treatment method of the bone fracture, as soon as possible to relieve pain, reduce the femoral neck fracture serious complications,reduce the mortality rate.

Objective To explore the effect of artificial femoral head replacement and total hip arthroplasty in treatment of elderly femoral neck fractures. Methods From January 2012 to December 2013 in our hospital 100 cases patients with elderly femoral neck fractures were selected according to the different treatment methods and were randomly divided into two groups, 50 cases in each group, The observation group patients treated with artificial femoral head replace-ment, the control group underwent total hip arthroplasty, the hip function recovery, two groups of patients with operation time, bleeding volume, postoperative drainage volume, duration of hospitalization and early or long-term complications were compared. Results The excellent and good rate of the observation group after treatment was 80.0%, was significantly lower than the control group after treatment (98.0%), the difference was statistically significant (P<0.05). The operative time, hospitalization in observation groups were shorter than the control group, the difference was statistically significant (P<0.05). The bleeding volume, postoperative drainage volume in observation group were significantly less than the control group, there was significant statistical difference (P<0.01). Early complications incidence rate of two groups had no significant statistical difference (10.0% vs 12.0%,P>0.05), long-term complications incidence rate of obser vation group was higher than that of the control group, the difference was statistically significant(12.0%vs 4.0%, P<0.05). Conclusion Artificial femoral head replacement and total hip have their own advantages in treatment of femoral neck fracture, arthroplasty, but the comprehensive effect, artificial femoral head replacement have the advantages of shorter operation time, less trauma, the long-term results after total hip replacement is superior to the artificial replacement of the femoral head, and no acetabular wear and other complications, total hip arthroplasty has certain advantages than ar-tificial femoral arthroplasty.

OBJECTIVETo investigate the association of maternal body composition and dietary intake with the risk of gestational diabetes mellitus (GDM).

METHODSA total 154 GDM subjects and 981 controls were enrolled in a prospective cohort study in 11 hospitals from May 20, 2012 to December 31, 2013. Bioelectrical impedance analysis and dietary surveys were used to determine body composition and to evaluate the intake of nutrients in subjects at 21-24 weeks' gestation (WG). Logistic regression analysis was applied to explore the relationships of maternal body composition and dietary intake with the risk of GDM morbidity.

RESULTSAge, pre-pregnant body weight (BW), and body mass index (BMI) were associated with increased risk of GDM. Fat mass (FM), fat mass percentage (FMP), extracellular water (ECW), BMI, BW, energy, protein, fat, and carbohydrates at 21-24 WG were associated with an increased risk of GDM. In contrast, fat free mass (FFM), muscular mass (MM), and intracellular water (ICW) were associated with a decreased risk of GDM.

CONCLUSIONMaternal body composition and dietary intake during the second trimester of pregnancy were associated with the risk of GDM morbidity.

Adult ; Asian Continental Ancestry Group ; Body Composition ; Body Mass Index ; Cohort Studies ; Diabetes, Gestational ; epidemiology ; Diet ; Diet Surveys ; Feeding Behavior ; Female ; Humans ; Pregnancy ; Pregnancy Trimester, Second ; Risk Factors

Animals ; Antibodies, Neutralizing/biosynthesis* ; Antibodies, Viral/biosynthesis* ; Body Weight/immunology* ; COVID-19/virology* ; Disease Models, Animal ; Disease Progression ; Humans ; Immunohistochemistry ; Lung/virology* ; Male ; Mesocricetus ; Nasal Cavity/virology* ; RNA, Viral/immunology* ; SARS-CoV-2/pathogenicity* ; Severity of Illness Index ; Viral Load