1.Changes of Nitric Oxide and Endothelin Levels in Children with Lymphoma and Its Clinical Significance
Journal of Applied Clinical Pediatrics 2006;0(15):-
Objective To investigate the changes and clinical signficance of nitric oxide(NO) and endothelin(ET) in children with lymphoma.Methods NO and ET of 39 cases with lymphoma and 33 normal controls were examined by using nitrose reductase method and RIA method.Results Compered to normal controls,NO and ET were higher in children with lymphoma;smilar to normal controls in complete remission(CR) and partial remission(PR);relapse cases were higher than remission.Conclusions NO and ET could have relation to lymphoma in children,testing the changes of NO and ET have signficanc to the assistant diagnosis,observeing effect and judging prognosis.
2.Scientific Research and Clinical Application of Stem Cell:a New Ethical Topic in Life Science Century
Chinese Medical Ethics 2015;(5):659-663
Based on the analysis on the most common type of scientific research and clinical application of stem cells, including embryonic stem cells , hematopoietic stem cells and mesenchymal stem cells as the breakthrough point, discusses common phenomenon and problems of ethics , scientific research and clinical study the moral life science century new topic, hope scientists, physicians, ethicists, caused by the administrative departments for pub-lic health thought , promote stem cells healthy and steady development .
3.Effects of Dexamethasone Combined with Intra-Amniotic Administration of Pulmonary Surfactant before Delivery in Preventing Neonatal Respiratory Distress Syndrome
dan, LIU ; hua, WEI ; yi-fei, ZHANG
Journal of Applied Clinical Pediatrics 2006;0(20):-
0.05),but the proportion of NRDS,the rate of mechanical ventilation dependence,and mortality had significant diffe-rences(Pa
4.Relationship of the change of calcitonin gene-related peptide and degeneration of the motor endplate after spinal cord injury in the rat
Qingmin ZHANG ; Hua GUAN ; Yi HONG
Chinese Journal of Rehabilitation Theory and Practice 2005;11(2):89-90
ObjectiveTo observe changes of calcitonin gene related peptide (CGRP) and aetylcholinesterase (AChE) in motor endplate (MEP) after complete spinal cord injury (SCI) in the rat.MethodsSCI model of Wistar rats were established by transecting T10 spinal cord completely. The venters of the tibial anterior muscle were taken at 1, 2, 4 and 8 weeks postoperatively to carry out the experiment.The changes of CGRP and AChE in the MEP were investigated with immunohistochemical test.ResultsAfter complete SCI, the quantity and distribution of CGRP decreased in MEP of 1-week sample, and the changes of AChE were observed until 4-week sample, and although the staining was light and sparse, CGRP and AChE existed in MEP during 2 months postoperatively.ConclusionThere is degeneration of MEP in skeletal muscle after upper motor neuron injury; CGRP and AChE are related to the degeneration of MEP; CGRP test can show the changes of MEP earlier.
5.Diagnostic value of 16-slices CT in urinary calculus
Yonghong ZHANG ; Xinghua ZHANG ; Jie ZHOU ; Hua ZHANG ; Xiaoming YI
Chinese Journal of Primary Medicine and Pharmacy 2011;18(4):453-454
ObjectiveTo explore the diagnostic value of 16-slices CT in urinary calculus. Methods25 cases of suspected urinary calculus were examined by 16-slices CT and some of these images were reconstructed with MPR. ResultsIn the 25 casces CT found 21cases of urinary calculus,among them kidney calculus 22 cases,urinary tract calculus 13 cases.In 5 of 21 cases,urinary calculus were not found with US.In all 6 cases urinary calculus were not detected by KUB and/or IVP. Conclusion16-slices CT was a valuable method in diagnosing urinary calculus.
6.Application of wireless network to field emergency medicine
Jun LI ; Jian-Hua ZHAO ; Shou-Bo ZHANG ; Yi ZHANG ;
Chinese Medical Equipment Journal 1989;0(01):-
Nowadays, LAN can't meet the requirements of field communication, and WLAN is playing more and more important role for its strong transmission ability and high mobility. This paper introduces the application of WLAN to filed medicine.
7.Expression of Id2 in Ewing sarcoma of bone and its significance
Yi DING ; Nana ZHANG ; Xiaoqi SUN ; Hua WANG
Chinese Journal of Clinical and Experimental Pathology 2015;(1):32-35
Purpose To study the expression of inhibitor of differentiation 2 (Id2) in Ewing sarcoma of bone as well as the correlation with cell cycle proteins. Methods The expression of Id2, c-Myc, Cyclin D1, p53, p16 and p27 in 45 cases of Ewing sarcoma were detected by immunohistochemical EnVision methods, the relationship between the expression of Id2 and clinicopathologic characteristics and the correlation with cell cycle proteins were analyzed. Results Total expression of Id2 was found in 88. 9% of Ewing sarcoma. Strong expression of Id2 was detected in 33. 3% cases. Higher frequencies of c-Myc and Cyclin D1 immunostaining were observed (66. 7% and 71. 1%, respectively), but lower frequencies of p53, p16 and p27 expression were present (20. 0%, 35. 6% and 28. 9%, respectively). Id2 overexpression displayed a negative relationship with p27 expression (P<0. 05). Among the follow-up of 24 cases, overexpression of Id2 was found more frequency in dead and metastases cases (41. 2%) when compared to that of progres-sion-free survival cases (14. 3%). Conclusions Id2 was extensively expressed in Ewing sarcoma of bone. Overexpression of Id2 and its correlation with p27 expression suggest that this is an important pathway involved in development of Ewing sarcoma. Moreover, Id2 overexpression may predict poor prognosis.
8.Drug Release Comparison of Nifedipine Sustained-release Tablets from Four Manufacturers
Yi WANG ; Changjuan ZHAN ; Wei XU ; Hua WANG ; Yong ZHANG
China Pharmacist 2014;(11):1856-1858
Objective:To compare the drug release of nifedipine sustained-release tablets from four manufacturers to evaluate the intrinsic quality. Methods:The drug release rate was determined by UV respectively with pH 1. 2 HCl solution, pH 4. 0 sodium ace-tate buffer, pH 6. 8 phosphate buffer and water as the dissolution medium. The dissolution curves were compared by f2 factor. Results:The drug release rate of nifedipine sustained-release tablets from the four manufacturers all met quality standard of our country, al-though the dissolution curves in the different dissolution medium was various. Conclusion:There are differences in intrinsic quality a-mong the nifedipine sustained-release tablets from the four manufacturers. The dissolution examination standard should be improved fur-ther.
9.MRI Manifestation of Temporomandibular Joint after Trauma
Hua WANG ; Xiaoying WANG ; Yi ZHANG ; Dongmei HE ; Xuexiang JIANG
Journal of Practical Radiology 1991;0(03):-
Objective To investigate MRI manifestations of temporomandibular joint trauma,emphasized on the displacement and deformation of the meniscus.Methods Thirteen patients with TMJ trauma were examined by MRI with 3-inch dual surface coils.T1WI and T2WI images in oblique sagittal and coronal plane were acquired in both closed-and open-mouth positions.Results Twenty(20/26,76.9%) joints had condylar fractures.Nineteen(19/20,95%) discs in 12 patients displaced anteromedially with the condylar fragments,six(6/20,30%) discs showed distortion and deformation.The other one patient had unilateral condylar fracture companied with avulsion and lateral dislocation of ipsilateral disc(1/20,5%),and the opposite disc also showed slight anterior displacement.Effusion was observed in 12(12/20,60%) joints with condylar fractures.The location of the discs didn't show obvious change between closed-and open-mouth positions.Conclusion MRI is an effective method for demonstrating TMJ injuries,and is useful for detecting the changes of morphology and position of the discs.
10.Hepatic resection for huge primary liver carcinoma
Shaogeng ZHANG ; Jingwang TAN ; Junbo CHENG ; Yi JIANG ; Hua LIN
Chinese Journal of General Surgery 1993;0(03):-
Objective To evaluate the safety and feasibility of hepatic resection for huge primary liver carcinoma (PLC). Methods 216 cases of huge PLCs(mean diameter of 14.2cm) were resected. The hepatectomies were performed under intermittent occlusion of hepatic inflow. Results All 216 cases were successfully resected. The mean time of occlusion of hepatic inflow was 19min, the mean blood loss was 743 ml. No serious complications occurred, and only seven patients died of hepatic failure and upper gastrointestinal haemorrhage postoperatively in this series. Conclusions Although resection of huge PLC is quite difficult, but if suitable surgical techique and perioperative management are adopted ,it is safe and feasible .