Objective:To investigate the effect of enhanced external counterpulsation(EECP)on serum nitric oxide(NO),malondialdehyde(MDA) and superoxide dismutase(SOD) in patients with coronary heart disease(CHD) and its mechanism.Methods:The serum NO,MDA and SOD levels of 54 cases of CHD and 20 normal controls were tested.Patients were divided into EECP group(30cases) and medication group(24 cases).The serum concentrations of NO,MDA and SOD of each group before and after treatment were compared for the correlation analysis.Results:Before treatment,compared with the normal controls,the serum levels in CHD patients were as follows.NO were much lower(P0.05).Correlation analyses showed that in EECP group,there was negative correlation between NO and SOD(r=-0.47,P

Animals ; Brain ; growth & development ; metabolism ; Emotions ; Glucocorticoids ; therapeutic use ; Humans ; Memory ; RNA, Messenger ; analysis ; Receptors, Glucocorticoid ; analysis ; genetics ; physiology

Cardiovascular Diseases ; complications ; prevention & control ; Diabetes Mellitus, Type 2 ; complications ; prevention & control ; Humans ; Metabolic Syndrome ; complications ; prevention & control

Epidermal growth factor (EGF) is a very important peptide growth factor,which is not only involving in a variety of ocular cell mitosis,proliferation and differentiation,but also participates in mediating the signal transduction between cell and cell,cell and matrix interaction and other biological functions.Corneal injury is a common and frequently occurring disease in ophthalmology,and it would lead to blindness without appropriate treatment.Researches showed that EGF can promote the repair and regeneration of wounded cornea.In recent years,these studies advance from animal experiment stage to clinical stage and also from the morphology evaluation stage to the genetics study stage.This paper provided an overview of EGF concept,its biological effectiveness,its relationship to corneal injury and its clinical application.

Epigenetics refers to the changes of heritable gene expression without modification of DNA sequences which is one of major research interest of human genome study post gene era. Epigenetics may play an important role in the pathogenesis of retinal diseases. Epigenetics modification in the regulation of gene expression and function mainly includes DNA methylation,histone acetylation and non-coding RNA such as miRNA. The implication of epigenetics has been suggested with the pathogenesis of retinal fibrosis, retinitis pigmentosa, age-related macular degeneration and diabetic retinopathy. In addition, the epigenetics drug has potential to be used in the treatment of retinal diseases.

To evaluate the curative effect and drug tolerance in the treatment of severe bacterial keratitis and conjunctivitis by levofloxacin.
●METHODS: Totally 195 patients with severe bacterial keratitis and conjunctivitis were included in this study. Based on the sequence of enrollment, they were randomly divided into three groups: group A ( 65 patients) received levofloxacin, group B ( 65 patients) received suture method under microscope, group C received suture method with loupe besides the same basic operative treatment in the two groups. The curative effect and drug tolerance were observed and compared statistically.
●RESULTS: ln group A, 54 cases were cured, in the rate of 83. 1%, 7 cases ( 10. 8%) were excellent, 3 cases (4. 6%) were valid, 1 case (1. 5%) was invalid. ln group B, 25 cases (38. 5%) were cured, 6 cases (9. 2%) were excellent, 23 cases (35. 4%) were valid, 11 cases (16. 9%) were invalid. ln group C, 4 cases (6. 2%) were cured, 3 cases (4. 6%) were excellent, 36 cases (55. 4%) were valid, 22 cases (33. 8%) were invalid. The curative effect and drug tolerance among groups had obvious differences (P<0. 05).
●CONCLUSlON: Levofloxaoin is effective and safe for the treatment of bacterial conjunctivitis and keratitis, which is not resistant and worthy of promotion.

Character Repertoires are supported by DICOM to encode Characters in different languages, in which UTF-8 and GB18030 are for Chinese characters. Each of them can replace Acquiesced Character Repertoire in Attribute Specific Character Set so that Chinese characters can be encoded in data elements. Utility programs compatible with DICOM are also required to support UTF-8 or GB 18030 for unerring representation and encoding.

Objective To investigate the diagnosis and therapy of Crohn's disease(CD).Methods The clinical data of 30 cases of pathologically proven CD from 1992 to 2005 were analyzed,26 cases were followed up.Results Among the 30 patients with CD,13(43.3%)diagmosed by endoscopy and biopsy.and17 cases(57.7%)were diagnosed by operation and pathology Before operation,6 cases were diagnosed as acute abdomen,4 cases as ileus,3 cases as massive hemorrhage of gastrointestinal tract,2 cases as colorectal cancer,1 case as intestinal fistula and 1 case as head mass of pancreas.Of the 26 cases followed up cases,15 cases accepted operation with 5 cases of recurrence;21 cases have taken drugs,and the total effective rate was 73.1%.Conclusions CD is a chronic relapsing disease and is difficult to diagnose.The majority of patients undergo operation due to misdiagnosis or complications.CD is prone to relapse postoperatively,quality of life is poor,and one must heighten awareness of these patients,make early diagnosis,directed therapy,and intensify follow up.

Objective To examine the expression of macrophage migration inhibitory factor(MIF)in lung tissues of rats with experimental pulmonary fibrosis and to discuss its effects on pulmonary fibrosis.Methods36 male SD rats were randomly divided into two groups:the pulmonary fibrosis group and the control group.Rat pulmonary fibrosis was induced by an intratracheal injection of bleomycin.The following tests were undedaken: HE and Masson staining of lung section,immunohistochemical staining of protein of MIF in the lung,RT-PCR of MIFmRNA in the lung.ResultsCompared with the control group,the mRNA and protein expression of lung MIF on day 7 to 28 in pulmonary fibrosis increased and reached the peak on day 14 after an intratracheal injection of bleomycin(P

The method of reinforcement and elimination are frequently used in TCM therapy on malignant tumor,as mediation method is seldom used.But Dr.CHEN Yi realizes that spirit being invalid is the key to the invasion of malignant tumor,and depression is the key to the pathogenesis of tumor,qi stagnation and blood stasis is its main characteristic.Under the guidance of the spirit-regulating and depression-relieving,on the base of mediation therapy,Dr.CHEN Yi uses Xiaoyao Powder,combined with the therapies of activating blood,dispelling dampness,resolving phlegm,purging the pathogenic fire,promoting digestion,in treating malignant tumor to dredge meridians,make qi and blood unobstructed,eliminate the stagnation,and it has gotten satisfactory results which include improving the patients’life quality,constraining tumor’s development,prolonging patients’ survival time.This text is a brief instruction to the application principle and theoretic basis of CHEN Yi’s law of regulating spirit and relieving depression in malignant tumor therapy.