The main treatment methods of macular edema (ME) are intravitreal injection of anti-vacular endothelial growth factor drugs, corticosteroids, retinal laser photocoagulation and pars plana vitrectomy (PPV). However, recurrent ME, epiretinal membrane formation and drug resistance have occurred to a part of patients, which is called refractory ME (RME). PPV with internal limiting membrane peeling (ILMP) has the potential of treating and relieving RME. PPV combined with ILMP can treat and relieve RME by removing the posterior vitreous cortex, or removing the epiretinal membrane or internal limiting membrane at the same time during surgery to relieve the traction between the vitreous body and the retina. However, due to the complex pathogenesis of ME, the therapeutic effects of PPV combined with ILMP on ME caused by different etiologies still need clinical studies to explore the best surgical methods for ME caused by different etiologies.

Morphology and relationships of piriformis and its tendon,and their relations withsciatic nerve in 100 cases have been observed in order to analyse the cause of sciatica.Piriformis was divided into four types and piriformis tendon into five types.In79% of piriformis there were additional origins.In 5% of cases synovial bursa waspresent below the end of piriformis tendon.The relation between piriformis andsciatic nerve was anomalous in 38%.Sciatic nerves and their branches in 16%passed between the two tendons of piriformis,and along the anterior or posteriorsurface of a tendon.It is concluded that various anomalous relationship between piriformis tendonand sciatic nerve is an important factor giving rise to sciatic pain.

1. The diameters, lengths and course of the posterior primary rami, posterior medial and posterior lateral branches of lumbar nerves were studied. The form, inner diameters and position of the osseous fibrous foramina, osseous fibrous canals and lumbdorsal fascia foramina on the upper margin of iliac crest through which the nerves pass were also studied.2. Basing on the observation of 174 sides of the specimens the composition and types of the superior clunial nerve of the Chinese were observed, and their positions and courses on the upper margin of the iliac crest, were described in detail.3. The method and theoretical basis of locating the superior clunial nerve on the upper margin of the iliac crest were proposed.4. Basing on the anatomical character of the posterior rami of the lumbar nerve, the cause of lumbar and lumbocraral pain and their operative approach were discussed.

The blood vessels supplying the anterior part of the iliac crest of 126 (84 males, 42 females) Chinese adult cadavers were observed. The findings are as following:1. The superficial circumflex iliac artery has an average external diameter of 1.45?0.41 mm and supplies mainly the skin and the superficial structures of the groin region and the region adjacent to the anterior superior iliac spine.2. The ascending branch of the lateral circumflex femoral artery has an average external diameter of 2.62?0.51 mm and supplies the tensor fasciae latae and the outer border of the anterior superior iliac spine.3. The deep upper branch of the superior gluteal artery has an average external diameter of 2.87?0.56 mm and supplies the glutei medius et minimus and the outer border of the anterior part of the iliac crest.4. The deep circumflex iliac artery has an average external diameter of 2.77?0.47 mm and may originate from above (18.0％), behind (41.5％), or below (40.5％) the inguinal ligament. It supplies the abdominal muscles adjacent to iliac crest and the inner border of the anterior part of the iliac crest.In this study particular attention was paid to investigating the course, branches, anastomosis of the deep circumflex iliac artery and its relationship to the anterior part of the iliac crest.5. The findings suggest that the deep circumflex iliac vessel may be used as a nutritive pedicle in free microvascular transplantation of the iliac bone.

Objective To investigate the changes of serum interleukin 8(IL-8) level in children with thyroid disfunction and its clinical significance in children with autoimmune thyroid disease(AITD).Method Serum IL-8 of 30 children with hyperthyroidism,16 children with hypotyroidism and 20 health children were detected by double antibody enzyme linked immunossorbent assay(ELISA).Results Serum IL-8 levels in hyperthyroidism and hypothyroidism children were significantly higher than that in controls(P0.05).With the remission of the diseases, IL-8 levels decreased; there was a significant difference between serum IL-8 levels in patients before and after therapy (P

Occupational Exposure ; prevention & control ; Risk Assessment ; methods

OBJECTIVETo record the electrical activities of Antirior cingulate cortex (ACC) neurons by in vivo multi-channel recording methods using the model of complete freund's adjuvant (CFA) induced conditioned place avoidance (C-CPA), which has been set up in our previous studies.

METHODSThe electrode was self-made and the CPA responses were recorded by in vivo multi-channel recording method.

RESULTS(1) The electrical activities of ACC neurons could be successfully recorded by the self-made electrode. (2) Before or after the injection of CFA, rats were respectively conditioned to the different place. The firing rates of ACC neurons in the CFA-paired place vs that in the non-CFA-paired place was (0.853 ± 1.377) imp/s vs (0.221 ± 0.971) imp/s (P < 0.05, n = 26). (3) The CPA responses in the CFA-paired place vs that in the non-CFA-paired place were (303.55 ± 61.77)s vs (140.32 ± 33.52)s(P < 0.05, n = 6).

CONCLUSIONThe firing rates of rACC (rostral Anterior Cingulate Cortex) neurons were involved in the occurrence of the affective pain.

Animals ; Electrodes ; Freund's Adjuvant ; Gyrus Cinguli ; cytology ; Neurons ; cytology ; Pain ; diagnosis ; Pain Measurement ; methods ; Rats ; Rats, Sprague-Dawley

Adolescent ; Adult ; Aged ; Case-Control Studies ; Central Nervous System Neoplasms ; cerebrospinal fluid ; diagnosis ; Child ; Female ; Humans ; Hyaluronan Receptors ; cerebrospinal fluid ; Leukemia ; cerebrospinal fluid ; Male ; Middle Aged ; Young Adult

Objective To study the expression of BRG1 gene in colon cancer and its relationship with histological grade and clinicopathological stages characteristics.Methods The expression of BRG1 -positive cancer cells were detected by immunohistochemistry in 100 cases of colon cancer,and the relationship with histological grade and clinicopathological stages characteristics was analyzed.Results Of the 100 colon cancer specimens analyzed,the positive expression rate was 82.0%.The expression of BRG1 in colon cancer tissue with histological grade and TNM staging was significantly different (χ2 =23.509,P =0.024;χ2 =25.659,P =0.002).The higher the histological grade,the stronger the BRG1 expression in colon cancer tissue.BRG1 expression in advanced colon cancer tissue was significantly enhanced in the early stage.Conclusion The appearance of BRG1 -positive cancer cells is associated with histological grade and clinicopathological stages characteristics.BRG1 might play an important role in the development of colon cancer.

Objective To explore the clinical characteristics of Henoch-Sch(o)nlein purpura complicated with acute necrotizing acute pancreatitis,in order to provide information for the diagnosis and differentiation of Henoch-Scht(o)nlein purpura complicated with acute abdominal disease.Methods There was a case present with purpura,abdominal pain,massive ascites and poor spirit in Department of Pediatrics,the First Affiliated Hospital of Zhengzhou University.The clinical manifestations and physical examination results were summarized and discussed,some pediatric specialists from nephrology department,surgery department,digestive system department were invited to discuss the case.The treatment was adjusted according to result of discussion,the final diagnosis was tracked.Results The case was firstly diagnosed with Henoch-Sch(o)nlein purpura,acute diffuse peritonitis with cause in dispute.After the discussion,the intestinal necrosis,perforation could not be excluded,acute pancreatitis required further identification.Exploratory laparotomy was received because of the changing condition after discussion.The intraoperative diagnosis was acute necrotizing pancreatitis.The patient recovered well with medical treatment.Conclusion When children with Henoch-Sch(o)nlein purpura had an acute abdominal disease,acute necrotizing pancreatitis should be considered in addition to intestinal necrosis,perforation.