1.The enhancement of the renal cortex and medulla and the renal function: a correlative study of conventional CT scan with glomerular filtration rate
Chinese Journal of Radiology 2010;44(9):958-962
Objective To study the relationship between the enhancement of renal cortex and medulla during the conventional CT scans with and without contrast enhancement and the renal glornerular filtration rate (GFR). Methods Thirty five cases with unilateral posternal obstructive hydronephrosis According to GFR, the 70 kidneys were divided into 4 groups: normal, slightly impaired, moderately impaired and severely impaired. In the cortical phase of enhanced CT scan, the enhancing intensity of the renal cortex and medullar was measured and following measures were calculated: CTce - CTcp, CTmc -CTmp,ratio of enhancement of affected and unaffected renal cortex and medullar, and the ratio of those of each case: CTac/CTnc, CTam/CTum, CTac/CTam, CTnc/CTnm, (CTac/CTam) / (CTuc/CTum). The differences of these measures in different groups were analyzed with one-way ANOVA and their correlation with GFR was studied with Pearson test. The best indicator to reflect enhancement of renal cortex was selected from these measures, and all the kidneys were divided into 4 groups accordingly: strong, less strong, medium and weak. Then its consistency with GFR groups were calculated. Result (1) The differences of CTce - CTcp ( 154. 98 ± 28. 70 ), ( 122.67 ± 39. 32 ), ( 81.30 ± 32.94 ) and ( 57.60 ±23.49) HU respectively, CTac/CTuc 0. 97 ±0. 09, 0. 79 ±0. 18, 0. 64 ±0. 24 and 0. 51 ±0. 13 respectively,CTam/CTum 0. 98 ±0. 26, 0. 89 ±0. 18, 0. 86 ±0. 31 and 0. 75 ±0. 28 respectively, CTam/CTum 2. 76 ±0. 35,2. 35 ± 0. 79, 1. 83 ± 0. 68 and 1.73 ± 0. 28 respectively, CTac/CTam and ( CTac/CTam)/( CTuc/CTum) 1.00 ±0. 28,0. 89 ±0. 34, 0. 75 ±0. 17 and 0. 69 ±0. 14 respectively of different GFR groups were evident( P < 0. 05 ) . ( 2 ) Positive correlation was found between GFR and CTce-CTcp ( r = 0. 887, P <0. 01 ), CTac/CTuc ( r = 0. 872, P < 0. 01 ), CTam/CTum ( r = 0. 504, P < 0. 01 ), CTac/CTam ( r =0. 772, P < 0. 01 ), (CTac/CTam) / (CTuc/CTum) ( r = 0. 663, P < 0. 01 ). ( 3 ) Selecting CTac/CTam to reflect enhancement of renal cortex, the diseased kidneys can be divided into groups of strong ( CTac/CTam ≥2. 60); less strong (2. 20 ≤CTac/CTam <2. 60); medium ( 1.80 ≤CTac/CTam <2. 20); and weak ( CTac/CTam < 1. 80). The consistency with GFR grouping was 80. 0%. Conclusions There is significant correlation between renal cortex-related indicators and GFR, especially CTac/CTam, which can be used as the indicator of renal function in patients with unilateral or bilateral postrenal obstructive hydronephrosis. The conventional contrast enhanced CT scan can be taken as a semi-quantitative method of GFR measuring with relative low X-ray dosage compared with CT perfusion.
2.Analysis of Re-treatment for Cervical Lymph Node Recurrence in Nasopharyngeal Carcinoma Patients after Radiotherapy
Chinese Journal of Clinical Oncology 2010;37(1):13-15
Objective:To investigate the efficacy of re-treatment for cervical lymph node recurrence in nasopharyngeal carcinoma patients after radiotherapy and to explore the prognostic factors.Methods:Eighty-two patients who received therapy due to cervical lymph node recurrence after deftnitive radiotherapy were reviewed.The relevant factors including sex.the interval between radiotherapy and recurrence,rN stage,recurrence site,treatment modalities,and treatment efficacy were analyzed.Subgroup analysis was performed to review the relevant factors including the involvement in the adjacent tissues,the number of positive nodes and surgical range.Kaplan-Meier method,Log-rank test and Cox method were used for statistical analysis.Results:The 1-,3-and 5-year local control rates were 58%,39.0%,and 39.0%,respectively.The 1-,3-and 5-year overall survival rates were 82.9%,47.6%.and 25.0%,respectively.The 1-,3-and 5-year overall survival rates in the radiotherapy-based treatment group were 80.8%,37.1%and 19.1%,respectively.The 1-,3-and 5-year overall survival rates in the surgery-based treatment group were 86.7%,66% and 34.2%,respectively.The efficacy of surgery-based treatment was superior to that of radiotherapy-based treatment.In the multivariate analysis,tumor recurrence site was an independent prognostic factor.Conclusion:Radical neck dissection-based treatment can achieve satisfactory efficacy for cervical lymph node recurrence after radiotherapy in nasopharyngeal carcinoma patients.
3.A medical consumable material management information system.
Chinese Journal of Medical Instrumentation 2014;38(3):229-234
Medical consumables material is essential supplies to carry out medical work, which has a wide range of varieties and a large amount of usage. How to manage it feasibly and efficiently that has been a topic of concern to everyone. This article discussed about how to design a medical consumable material management information system that has a set of standardized processes, bring together medical supplies administrator, suppliers and clinical departments. Advanced management mode, enterprise resource planning (ERP) applied to the whole system design process.
Disposable Equipment
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Management Information Systems
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Materials Management, Hospital
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Software Design
4.A Medical Devices Management Information System Supporting Full Life-Cycle Process Management.
Chinese Journal of Medical Instrumentation 2015;39(4):304-309
Medical equipments are essential supplies to carry out medical work. How to ensure the safety and reliability of the medical equipments in diagnosis, and reduce procurement and maintenance costs is a topic of concern to everyone. In this paper, product lifecycle management (PLM) and enterprise resource planning (ERP) are cited to establish a lifecycle management information system. Through integrative and analysis of the various stages of the relevant data in life-cycle, it can ensure safety and reliability of medical equipments in the operation and provide the convincing data for meticulous management.
Equipment and Supplies
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Management Information Systems
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Reproducibility of Results
5.Study of the individualized health management of senile mental disorders
Chinese Journal of Geriatrics 2014;33(8):884-886
Objective To evaluate the effect of the individualized health management on senile mental disorders.Methods 421 patients with senile mental disorders were randomized into two groups:the intervention group (n =213) received routine antipsychotic drugs treatment,health education and individual health management,and the control group(n=208) received only population health education and routine drug antipsychiatric treatment.Results The Brief Psychiatric Rating Scale (BPRS) scores in two group were significantly higher after treatment than before treatment (all P<0.01).The BPRS score in each period after treatment were significantly higher in intervention group than in control group (all P<0.01).The mini mental state examination (MMSE) score in two treatment groups were significantly higher after treatment than before treatment (all P<0.01).The MMSE score in each period after treatment were significantly higher in intervention group than in control group (all P<0.05).Conclusions The individualized health management in senile mental disorders is not only feasible,but also effective.
6.Research of a System for Computer Assisted 3D Puncture
Chinese Medical Equipment Journal 2003;0(11):-
Objective To research a computer assisted 3D puncture system. Methods The system drew lessons from the method of CAS. MITK and the frame of X-knife were used to design the machine arm independently. Result The system came to the designing standard by experiments. Conclusion The clinical demanded product is developed with lower price in shorter time by integrating the mature techniques.
7.Research and Solution of Information Technology Operation and Maintenance Management System of the Hospital Based on Realtime Intelligent Infrastructure Library (RIIL)
Journal of Medical Informatics 2017;38(6):22-26
The paper analyzes detailedly the current problems and challenges of Information Technology (IT) operation and maintenance management of the hospital,and states the logical architecture,deployment architecture,functional modules and application effect of Realtime Intelligemt Infrastructure Library (RIIL),in order to improve the efficiency of IT operation and maintenance work.
8.CHANGES IN PLASMA ?-EP, Dyn AND LEK CONTENTS IN PATIENTS WITH ESSEN TIAL HYPERTENSION AND THEIR CLINICAL SIGNIFICANCE
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
In this study, radioimmunoassay (RIA) was perfomed to measure the contents of opiate peptide in plasma in control group and essential hypertension (EH) group before and after treatment. The relationship between the changes in opiate peptide content and mean artery pressure (MAP) was analysed. The results showed that the contents of ?-endorphin (?-EP) and leuenkephalin (LEK.) in the EH group were lower significantly (P
9.Study on Making the Animal Model of Diarrhea-predominant Irritable Bowel Syndrome Due to Liver-Spleen Disharmony
Journal of Traditional Chinese Medicine 1993;0(06):-
Objective To explore the animal model making method for diarrhea-predominant irritable bowel syndrome (IBS-D) caused by the disharmony of liver and spleen in TCM.Methods In order to define the period of the animal model making,the 32 neonatal rats were divided into 3 days group,6 days group,9 days group and control group.In order to determine the weight of the experimental rats,the 48 rats with different weight were divided into lower weight model group,lower weight control group,medium weight model group,medium weight control group,higher weight model group and higher weight control group.In order to decide the method of causing diarrhea,the 32 rats were divided into lactose enriched diet group,restraint stress group,lactose enriched diet plus restraint stress group,and a control group.The body weight and diarrhea rate of all groups were compared respectively.After the method of model making was decided,the 16 rats were divided into a model group and a control group,and 5-hydroxytryptamin (5-HT),lactate dehydrogenase (LDH) and aquaporin 4 (AQP4) of the two groups were compared for model-proving.Results Based on the results step by step,the best method was decided:the period of the animal model making was 6 days,rats with higher body weight should be subjects,and the lactose enriched diet combining with restraint stress should be used to induce diarrhea.Model-proving test:compared with the control group,5-HT and LDH decreased (P
10.Design and Implementation of Mobile Medical Model Based on Smart Phone
Journal of Medical Informatics 2017;38(3):22-25
Taking the pulse signal as an example,the paper designs mobile medical system software on the smart phone,uses mobile phone to collect the pulse signal and realizes transfer and analysis form self-organized medical data sharing network,so as to meet the user's demands better.