Objective To study clinical and pathological characteristics and effects of arthroscopic treatment of ankle soft tissue impingement syndrome(ASTIS). Methods A total of 21 cases of ASTIS underwent arthroscopic operations from November 2000 to April 2005.The impingement soft tissues were removed under arthroscope at 13.6?9.9 months after injury.The resected tissues were pathologically examined following surgery.The efficacy of arthroscopy was assessed using the American Orthopaedic Foot and Ankle Society(AOFAS) rating scores. Results Arthroscopic findings showed the most common impingement tissue was synovium(20 cases),followed by distal fascicle of the anterior tibiofibular ligament(5 cases),fibrous scar tissue(4 cases),anterior talofibular ligament(3 cases),and meniscoid tissue(3 cases).ASTIS accompanying cartilage injuries was found in 16 cases.All the cases were followed for 7~60 months(mean,34.3?9.4 months).The AOFAS scores significantly increased postoperatively than preoperatively,with total scores from 67.0?9.7 to 94.0?6.4(t=-7.205,P=0.000) and subjective scores from 20.7?6.6 to 35.7?4.9(t=-5.003,P=0.000). Conclusions Ankle soft tissue impingement syndrome often occurs after ankle sprain along the anterolateral portion of the ankle.Common impingement tissues are synovium,ligament,scar tissue,and meniscoid tissue.Arthroscopic treatment of ankle soft tissue impingement syndrome is satisfactory.

OBJECTIVE To study the risk factors of pulmonary infection and prognosis in elderly cerebral apoplectic patients. METHODS A retrospective survey on 541 elderly cerebral apoplectic patients was analyzed to investigate the rate of pulmonary infection,the type and the severity of cerebral apoplexy,the underlying disease,disturbance of consciousness,invasive operation and the prognosis. RESULTS The most of the pulmonary infections in elderly cerebral apoplectic patients were nosocomial infection.The rate of infection was high and related to many factors. CONCLUSIONS The result showed that the pulmonary infection in elderly cerebral apoplectic patients is caused by many risk factors.Controlling the rate of pulmonary infection can help us to succeed in treating cerebral apoplexy.

[Summary] Long noncoding RNA( lncRNA) plays an important role in regulating the life activities, and its disordered expression is closely related to many diseases. Several studies have shown that lncRNA could modulate the endocrine metabolic processes at transcription, post-transcription, and the epigenetic modification levels, but the exact mechanism is still unclear. Further research needs to be done. This review will briefly describe the research progress of lncRNAs in endocrine and metabolic respects.

Defensin is a cysteine-rich, low molecular weight and cationic antimicrobial peptide. Human breast milk con-tains high level of defensin. The defensin in human breast milk can not only inhibit the growth of various pathogenic microorgan-isms, but also promote the development of infant immune system and reduce the incidence of infantile upper respiratory infection. Nowadays, the roles of defensin in breast milk is more recognized. This paper focuses on the molecular characteristics of human defensin, its antibacterial and antiviral roles, and the latest progress in defensin research.

Tyrosine kinase inhibitor (TKI) may significantly improve the treatment outcome in chronic myeloid leukemia (CML).It is the most frequent question about whether the patients with durable complete molecular response (CMR) can safely discontinue TKI treatment without relapse.This has focused attention on the strategies to eradicate residual CML cells,especially the CML stem cells,which should result in long term leukemia-free survival and permanent cure.Here,the progress on discontinuation of TKI therapy and alternative approaches to eradicating CML stem cells in the 55th ASH annual meeting is reviewed.

SUMO (small ubiquitin-related modifier) is involved in the post-translational modifications of proteins,and this process is referred to as SUMOylation.SUMOylation plays an important role in the regulation of cellular activities such as strengthening the stability of the protein,nucleocytoplasmic transport,DNA repair,DNA replication,mitotic and meiotic chromosome behavior,et al.SUMOylation is a dynamic process and can be reversed by SUMO-specific proteases (SENP).Once the balance between SUMOylation and de-SUMOylation is broken,there will be an aberrant expression of SUMO or SENPs in cells to happen,which may lead to the tumor occturtrence.

Objective:To analyze and compare the effect of integration of Traditional and Western Medicine treatment and western treatment for patients with severe acute pancreatitis.Methods:According to the including criteria,nineteen randomized controlled trials of this topic were enrolled into the analysis.The detail about the trial design characters of the subjects, results of the studies were reviewed and analyzed by Revman 4.1 software.Results:Compared with integration of Traditional and Western Medicine treatment,western treatment was associated with a significantly higher incidence of mortality(RR=0.35,95%CI 0.25～0.48,P

The mercury content in soil and sediment, although minimal, but its toxicity is substantial.Different speciation of mercury has different toxicity, so the determination of total mercury can not fully reveal its toxicity and bioavailability.The speciation of mercury has become more and more indispensable.This paper summarizes the extraction and determination methods of the total and the speciation mercury in soil and sediment, and the extraction and determination of methyl mercury.

Objective To investigate the effect of tonic pain stimulation on the attention network test (ANT) . Methods Twenty healthy males recruited from university were enrolled in this study, and laboratory pain was induced by cuff pressure stimulation on the upper arm. All subjects performed the task separately under pain, no-pain and pressure conditions. The reaction time and accuracy rate of the ANT were quantified. The subjective pain perception was assessed by the short-form McGill Pain Questionnaire ( SF-MPQ) . Results Across three conditions, the executive network showed significant pain effect (F = 76.31 , P< 0.001) : no-pain condition at (92.51 ±35.71 )ms, pressure condition at (94.06 ±25. 28) ms, pain condition at ( 120.24 ± 18.21 )ms. Furthermore, the average reaction time and the A-scores (i. e. affective words) in SF-MPQ caused by pain was positively correlated ( r = 0.11, P = 0.03) . Conclusion Pain can result in deficit in the executive network for attention regulation. The negative affections caused by pain can interfere with attention.

Objective To investigate the effects of titanium nitride(TiN) coating on corrosion resistance of dental Co-Cr alloy in the simulated oral environment. Methods The Co-Cr alloy commonly used was casted with specimen sized of 10 mm× 10 mm×3 mm. Then the specimen was coated with a thickness of 2.5 μm TiN coating on the surface by multi-arc physical vapor deposition. The Tafel polarization curves of the specimen before and after coating titanium nitride in artificial saliva were measured by electrochemical station. Results From the Tafel polarization curves, the specimen after coating TiN showed that both anodic polarization curve and cathodal polarization curve were fiat, natural corrosion potential moved to the positive way, and passivation interval got longer. From the annular anodic polarization curves, the specimen after coating TiN had almost no "delay area". Conclusion TiN coating can improve corrosion resistance of Co-Cr alloy.