Objective] To further investigate the academic thoughts and the aspects of clinical treatments of Lu Yuanlei focused on hemorrhage syndrome. [Methods]According to study straightly the compilation of medical records of Lu Yuanlei and his academic works, the scientific explanation toward the therapeutic methods for hemorrhage syndrome and especially both the theoretical thoughts and the clinical experience of hemoptysis and hematochezia are discussed and concluded. [Results] Lu Yuanlei concluded the three major principles of healing hemorrhage syndrome. To emphasize the importance of patients with sufficient healthy qi inside as well as to make well use of Bupleurum based on syndrome differentiation in the clinical treatments. In addition, with the caution of stopping bleeding without blood stagnation, from our survey, there are three frequently used pairs of drugs specialized for hemostasis in the medical records of Lu Yuanlei. Furthermore, Lu Yuanlei demonstrated three distinguished opinions in the examination of enterorrhagia , to apply Huang Tu Decoction deliberately for the clinical treatment of hematochezia. [Conclusion] The valuable academic inspiration and clinical treatments of hemorrhage syndrome proposed by Lu Yuanlei can be meditated and preached. Besides, his academic viewpoints of scientific connotation of TCM are obviously prominent in the contents.