To evaluate the effect on loe-dose enalapril(ACE inhibitor), we administered a single dose of 10 mg/day enalapril to 22 patients(6 mild hypertension and 16 moderate hypertension) for 12 weeks. The systolic and diastolic blood pressures of patients were declined significantly at 4th week and at 12th week(p<0.005) without significant change of rate and body weight. These data were also analyzed in terms of the percent of patients with marked, moderate and mild responses. Enalapril yielded a 72.7% response rate in marked fall and 22.7% response rate in moderate fall which revealed 95.4% of good response rate. Enalapril was tolerated and showed no significant clinical and biochemical adverse reactions. In conclusion, these results indicate that monotherapy with enalapril 10 mg in a single daily dose was effective in the management of mild to moderate uncomplicated essential hypertension and was well tolerated.
Body Weight ; Enalapril* ; Humans ; Hypertension*

The purpose of this study was to investigate the effect of a hand massage program on anxiety, vital sign and pain in clients with ischemic heart disease. The design utilized for this study was quasi-experimental with a nonequivalent control group non-synchronized design The subjects were fifty-four patients, twenty-eight for the experimental and twenty-six for the control group, who were admitted with ischemic heart diease at a cardiac intensive care unit in K medical center of K university. This study was carried out from May, 1999 to March, 2000. The level of anxiety and pain measured by Visual Analogue Scale, systolic blood pressure, diastolic blood pressure and pulse rate were measured before and after hand massage, the state of Anxiety was measured by the Spielberger (1970) scale at admission and after hand massage for three days. The collected data were processed by using the SPSS PC program and analyzed using X2 -test and t-test. The result of this study are as follows: 1. The scores of VAS anxiety and State of anxiety of the experimental group were lower than those of the control group. 2. The degree of systolic blood pressure, diastolic blood pressure and pulse rate of the experimental group were lower than that of the control group. 3. The score of VAS pain of the experimental group was lower than that of the control group. The results suggested that hand massage can decrease VAS anxiety, State of anxiety, vital signs and VAS pain of patients who were admitted with ischemic heart disease at cardiac intensive care unit Therefore, it is proposed that hand massage is an appropriate nursing intervention to relieve anxiety of the patients who were admitted with ischemic heart disease at a cardiac intensive care unit.
Anxiety* ; Blood Pressure ; Hand* ; Heart Rate ; Heart* ; Humans ; Intensive Care Units ; Massage* ; Myocardial Ischemia ; Nursing ; Vital Signs