2.Antihypertensive Effect of Saikokaryukotsuboreito Accompanied by Objective Changes in Autonomic Balance
Hiroshi ODAGUCHI ; Akino WAKASUGI ; Hidenori ITO ; Hisakazu SHODA ; Yuji GAMO ; Koji WATANABE ; Takayuki HOSHINO ; Tetsuro OIKAWA ; Toshihiko HANAWA
Kampo Medicine 2008;59(1):53-61
We report the case of a 46-year-old man with hypertension whose blood pressure decreased due to saiko-karyukotsuboreito consumption.The patient also presented with some symptoms that suggested autonomic imbalance. After consuming 7.5g/day of a spray-dried powder of saikokaryukotsuboreito (Tsumura & Co.) for 3 months, his blood pressure measured at office was considerably lower. Twenty-four hour ambulatory blood pressure monitoring revealed that the surge in morning blood pressure, which is considered to be a risk factor for cerebrovascular disease, diminished in addition to the 24-hour mean blood pressure. A postural test revealed that his autonomic balance, which had been in a sympathetic dominant state, was inversely inclined to a parasympathetic dominant state.Our case report suggests that saikokaryukotsuboreito acts on the autonomic nervous system, which in turn exerts an antihypertensive effect, and that this effect is helpful in lowering the blood pressure in hypertensive patients whose autonomic balance is impaired due to stress.
Blood Pressure
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Assessment of balance
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Hour
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Effective
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Equilibrium
3.Four Cases Report of Dumping Syndrome Effectively Treated with Keishito and its additional Prescription
Kazuhiko NAGASAKA ; Hidehiko FUKUDA ; Michio NATORI
Kampo Medicine 2008;59(3):495-497
We report four patients suffering from dumping syndrome treated effectively with Keishito and its additional prescription. Case1was a 57-year old male who received subtotal gastrectomy 30 years ago. After the operation he felt shaking sensations and eyes flickering after meals for10minutes to 4 hours. These symptoms tended to occur along with hunger. After taking Keishito, these symptoms improved. Case 2 was a 63-year old male who received subtotal gastrectomy 7 years ago. In recent years, he has had noticeable sweat and fatigability 20-30 minutes after meals. After taking Keishito, these dumping syndrome symptoms disappear. Case 3 was a 71-year old female who received subtotal gastrectomy 9 years ago. Thereafter, cold sweats and dizziness came to appear regardless of what she ate. After taking keishikashakuyakuto or shokenchuto the aforementioned symptoms disappeared. Case 4 was a 72-year old female who received subtotal gastrectomy 2 years ago. Sweats and hot flushes began to occur after meals for 30 minutes to 3 hours, from last July. These symptoms were improved simply by licking candy. After taking Keishito, these symptoms also disappeared.
symptoms <1>
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Gastrectomy
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Dumping Syndrome
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Cases
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Hour
4.The effect of health and nutrition management classes on nutrition choices: A case study on diabetics in Huntsville, Alabama, United States.
Malcolm A. Cort ; Marta Sovyanhadi
Malaysian Journal of Nutrition 2007;13(2):141-148
This study evaluated the effectiveness of a one-day nutrition education seminar utilizing a sample of 26 confirmed diabetics who had at least once before, participated in nutrition classes. The participants were exposed to a seminar that promoted, evaluated, and rewarded good nutrition choices in an effort to educate this group about coping with diabetes through nutrition management. A 24-hour food recall was used as a pre-test, meal plans constructed by trained graduate-level diet interns were used as the standard by which proper nutrition was judged, and participants’ choices were used as the post-test evaluation. Significant differences were found between the 24-hour recall and the ideal meal plans in all of the three nutrient measured (energy, protein and fat). Participants showed a preference for personally constructed meal plans as opposed to those constructed by the interns. However, significant diet adjustments were shown in the short term. Discussion focused on the need for repeated involvement in diet interventions, and the challenges faced in changing diet habits of a group of middle-aged individuals who are even slightly obese.
Nutritional status
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Diet
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Hour
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Case Studies <2>
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United States
5.Enterovirus 71 infection induces apoptosis in Vero cells.
Yoke-Fun Chan ; Sazaly Abubakar
The Malaysian journal of pathology 2003;25(1):29-35
The effects of Enterovirus 71 (HEV71) infection on African green monkey kidney cells (Vero) were investigated. It was found that the infected cells showed progressive cellular morphological changes characteristic in apoptotic cells within 10 hours post-infection. The number of apoptotic cells correlated significantly with the number of HEV71 antigen positive cells when cells were labeled using terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end labeling (TUNEL) and stained for HEV71 antigen. Approximately 11, 26, 45 and 50% of the infected cells were apoptotic at 12, 24, 48 and 72 hours post-infection, respectively. Internucleosomal DNA fragmentation, characteristic in the late stage of apoptosis was noted beginning on day 2 post-infection. The DNA fragmentation, however, was absent in cells treated with the heat- and ultraviolet light-inactivated virus inocula. These results demonstrate the capacity of HEV71 to induce apoptosis in the infected cells. The induction, however, requires high level of HEV71 infectivity and the presence of live virus particles, suggesting the need for the presence of specific viral proteins for apoptosis to occur.
Infection as complication of medical care
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Apoptosis
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seconds
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Enterovirus
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Hour
6.The assessment of patients' waiting and nursing consultation times at urban clinics in the National Capital District, Papua New Guinea.
Papua and New Guinea medical journal 2003;46(1-2):46-52
This study was conducted in the National Capital District during the months of August, September and October 2000. The study sites were the 3 urban clinics situated in the suburbs of Six Mile, Hohola and Konedobu. The aim of the study was to determine the patients' waiting times and nursing consultation times in the urban clinics. A total of 1075 patients were surveyed, including 264 children under 5 years of age. 58% of patients were males. 24% of patients were able to see a nurse within 30 minutes and 70% within 2 hours. 47% had to wait 1-3 hours to see a consulting nurse and a further 9.5% had to wait 3-5 hours. 67% of nursing consultations were 5 minutes or less, which is too short to interview, examine and prescribe treatment for the patients and to use the Paediatric 10 Steps. The short consultations of 5 minutes or less did not involve children under 5 years of age. There were only one to two nurses seeing the patients when 79% of patients were seen. This explains why the patients' waiting time was long. After consultations many patients (71%) were able to get their treatment within 30 minutes but 28% had to wait from 30 minutes to 2 hours for their treatment. The small number of nurses giving treatment leads to long waiting times. From the time of entry to exit out of the clinic, only 11% of patients spent 30 minutes or less in the clinic while 51% spent between 1 and 3 hours. The patients' waiting times and the short nursing consultation times are directly related to the insufficient number of nursing officers working in the clinics.
nursing therapy
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Hour
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waiting time
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therapeutic aspects
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seconds