Objective:To investigate the recognition degree and influence factors of adverse drug reactions and drug safety.Method:By means of multiphase random sampling,the interviewees filled in the questionnaires on the spot. The data were input with EpiData 3.1 and analyzed with software SAS 9.1.Result:5474 eligible questionnaires were obtained and the recovery rate was 81.69%.The interviewees had a good recognition of basic ADR knowledge,administration knowledge and rational drug use,but a poor recognition of pharmacovigilance.There were some differences in recognition between different regions,units and positions.The mono-factor analysis suggested that the recognition degree was related with regions,unit types,and length of service,culture degrees and professional titles.The multi-factor analysis suggested that the recognition degree was highly related with regions,unit types,culture degrees and professional titles.Conclusion: The interviewees have a better recognition of basic ADR knowledge than pharmacovigilance knowledge.There are differences in the recognition between different regions and units.It is imperative to provide special training courses for healthcare professionals according to different regions and units,so as to improve their consciousness of ADR reporting and promote the development of ADR monitoring.

Objective:To understand the occurrence of drugs-induced arrhythmia,and provide reference for clin- ic administration.Method:ADR reports of arrhythmia caused by drugs in Jiangsu Province from 1 Jan,2004 to 31 Dee, 2006 were analyzed.Result:The drugs which induced arrhythmia were those of cardiovascular drugs and anti-microbes. And many of these occurred during treatments.Conclusion:Clinic reasonable administration of drugs,careful observation and treatment should be enhanced.

Objective To investigate the predictive values of hemostatic activity of platelets on prophylactic transfusion,and determine the threshold of prophylactic platelet transfusion to avoid the bleeding risk caused by thrombocytopenia.Methods One hundred and twenty-seven patients whose platelet count(Plt)