1.Two Cases of Yersinia Pseudotuberculosis Infection with Acute Renal Failure in Pusan Province.
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):187-191
The usefulness of E-cadherin immunostaining as a marker of malignancy in the body fluids was investigated in the present study. Thirty-three histologically proven cases of cell blocks from the pleural, peritoneal, and pericardial fluids were studied by immunocytochemistry for E-cadherin antibody using LSAB method. These cases were cytologically diagnosed as adenocarcinoma (25 cases) and atypical cells (8 cases). Tumor cells showed strong positive membranous staining for E-cadherin antibody in 21 out of 25 cases (84%) of adenocarcinoma. E-cadherin staining was not found in 6 of 8 cases of suspicious maligancy. The sensitivity and specificity were 84% and 75%, respectively. Reactive mesothelial cells and inflammatory cells scattered were all negative. In conclusion, E-cadherin is an useful adjunctive marker to distinguish reactive mesothelial cells from the carcinoma cells in the body fluids.
Sensitivity and Specificity
;
Adenocarcinoma
;
Neoplasm Metastasis
2.Clinical Effect of Transurethral Needle Ablation (TUNA) in Durg Refractory Chronic Nonbacterial Prostatitis : Initial Experinece.
Phil Bum JUNG ; Jae Hoon WHANG ; Jeong Gu LEE
Korean Journal of Urology 2000;41(12):1490-1494
No abstract available.
Needles*
;
Prostatitis*
3.A clinical study on childhood epilepsy.
Jong In BYUN ; Young Hoon KIM ; In Goo LEE ; Kyung Tai WHANG
Journal of the Korean Child Neurology Society 1993;1(1):99-105
No abstract available.
Epilepsy*
4.Modulatory Effects of Imipramine on Pilocarpine-induced Seizures in Immature Rats.
In Goo LEE ; Young Hoon KIM ; Kyung Tai WHANG
Journal of the Korean Child Neurology Society 1998;5(2):207-216
PURPOSE: Norepinephrine has modulatory effects on neuronal excitability and, in some cases, has a proconvulsant effect. Intraperitoneal imipramine treatment increases norepinephrine level, and to a lesser extent, dopamine and serotonin in brain dialysate from rats. We sought to determine the effects of imipramine on pilocarpine-induced seizures in the immature rats. METHODS: Right and left cortical and hippocampal electrodes were placed in 10~15 day old Sprague-Dawley rats. The following day 3-hour video EEG recordings were obtained to monitor electrographic seizures and status epilepticus induced by intraperitoneal injection of high dose(200mg/kg : HD) and low dose (75mg/kg : LD) pilocarpine. A first group of rats received HD pilocarpine alone(n=25), or pretreatment with 0.5(n=6). 1(n=6), 2(n=6), 5(n=6), or 10(n=11)mg/kg of imipramine. A second group of rats received LD pilocarpine alone(n=6) or pretreatment with 2mg/kg of imipramine (n=6). Data were analyzed using the Fisher exact test. RESULTS: Treatment with HD pilocarpine alone resulted in electrographic seizures in 76%(n=19) and status epilepticus in 44%(n=11). In the HD pilocarpine group, status epilepticus was seen in 100% of rats pretreated 1, 2, and 5mg/kg imipramine. 90.9% of the rats pretreated with 10mg/kg of imipramine developed seizures and 36.4% developed status epilepticus. Imipramine at 0.5, 1,2, and 5mg/kg increased the incidence of seizures and status epilepticus in the HD pilocarpine group, but the incidence was statistically significant only for status epilepticus(p<0.05). The latency for the occurrence of first status epilepticus was 12.3+/-1.3 min in the HD pilocarpine alone group, and it was 21+/-3.8 min and 25.3+/-5.7 min in the group pretreated with 5 and 10mg/kg imipramine, respectively(p<0.02). Treatment with LD pilocarpine alone resulted in seizures in 50% and status epilepticus in 16.7%. In the LD pilocarpine group with imipramine 2mg/kg pretreatment, 83.3% had seizures and status epilepticus. Imipramine at 2mg/kg increased the incidence of seizures and status epilepticus in the LD pilocarpine group, but the increase was statistically significant only for status epilepticus(p<0.05). CONCLUSION: Imipramine exhibits a proconvulsant effect at low doses and an anticonvulsant effect at high doses in the pilocarpine seizure model in immature rats. There may be a dose-dependent effect on monoaminergic receptors which results in increased neuronal excitability.
Animals
;
Brain
;
Dopamine
;
Electrodes
;
Electroencephalography
;
Imipramine*
;
Incidence
;
Injections, Intraperitoneal
;
Neurons
;
Norepinephrine
;
Pilocarpine
;
Rats*
;
Rats, Sprague-Dawley
;
Seizures*
;
Serotonin
;
Status Epilepticus
5.Immunologic Changes in Bronchial Asthma on Immunotherapy.
Joon Sung LEE ; Kyung Tai WHANG ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1990;33(9):1255-1261
No abstract available.
Asthma*
;
Immunotherapy*
6.Intramedullary Nailing in Osteogenesis Imperfecta
Kuhn Sung WHANG ; Il Hoon SUNG ; Sung Joon KIM
The Journal of the Korean Orthopaedic Association 1990;25(6):1624-1632
Osteogenesis imperfecta is a heterogenous group of inherited disorder, which has abnormalities in the synthesis of collagen. Among variable clinical manifestations, orthopaedic clinical features are laxity of ligament and deformities arising from frequent fractures or angulation due to skeletal fragility. We had managed 4 cases of osteogensis imperfecta, which were belonged to type IV-B in two cases, type I-A in one, and type I-B in remained one by Sillence classification and they had suffered from recent fractures or deformities due to previous fractures in the long bones of the lower extremities. These patients had been treated with various types of intramedullary nails, such as Bailey-Dubow extensile rod. Rush rod and Kuntcher nail, and the result of intramedullary nailing lead to improvement of walking ability.
Classification
;
Collagen
;
Congenital Abnormalities
;
Fracture Fixation, Intramedullary
;
Humans
;
Ligaments
;
Lower Extremity
;
Osteogenesis Imperfecta
;
Osteogenesis
;
Walking
8.A Case of Congenital Esophageal Duplication Cyst.
Kyoung Hoon CHOI ; Chung Ah WHANG ; Byung Ju JEAUNG ; Kyu Earn KIM ; Ki Young LEE
Journal of the Korean Pediatric Society 1990;33(1):111-116
No abstract available.
9.A case of broad QRS paroxysmall supraventricular tachycardia that is difficult to differentiate from ventricular tachycardia.
Hung Ki MIN ; Hyun Hi KIM ; Jong Wan KIM ; Kyung Tai WHANG ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1992;35(2):257-262
No abstract available.
Tachycardia, Supraventricular*
;
Tachycardia, Ventricular*
10.A Case of Moyamoya Disease with Focal Seizure.
Man Gee HONG ; Hak Ki KIM ; Kyung Tai WHANG ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1982;25(10):1053-1057
No abstract available.
Moyamoya Disease*
;
Seizures*